|1.||Wu, Dong Fang: 1 article (01/2013)|
|2.||Schümann, Michael: 1 article (01/2013)|
|3.||Zhou, Lichun: 1 article (01/2013)|
|4.||Yang, Dezhi: 1 article (01/2013)|
|5.||Chaurasiya, Shyambabu: 1 article (01/2013)|
|6.||Sharon, David: 1 article (01/2013)|
|7.||Yang, Hong: 1 article (01/2013)|
|8.||Hitt, Mary M: 1 article (01/2013)|
|9.||Guo, Zhong Mao: 1 article (01/2013)|
|10.||McPherson, Robyn: 1 article (01/2013)|
07/01/2009 - "A significant improvement in viral replication and the antitumor effect was observed when the PKR inhibitor 2-aminopurine was coadministered with HSV-G47Delta to the tumor. "
01/01/1985 - "2-Aminopurine is much less potent than 6-N-hydroxylaminopurine in inducing gene mutation in mammalian cells in culture and this corresponds to the relative activity of these two compounds in inducing tumors in rats and neoplastic transformation of Syrian hamster embryo cells in culture. "
05/15/1999 - "To assess the possibility that selected purine analogues may affect tumor neovascularization, 6-methylmercaptopurine riboside (6-MMPR), 6-methylmercaptopurine, 2-aminopurine, and adenosine were evaluated for the capacity to inhibit angiogenesis in vitro and in vivo. "
01/13/1992 - "In the present study, 2-aminopurine, which has been reported to selectively block c-fos gene expression, was used to test the hypothesis that c-fos protein might be involved in the desensitization to catecholamines was observed in 2-aminopurine-treated C6-2B rat glioma cells. "
01/13/1992 - "2-Aminopurine inhibits RNA and protein synthesis and reduces catecholamine desensitization in C6-2B rat glioma cells."
01/01/2002 - "Lipopolysaccharide-induced impairment of classical swine fever virus infection in monocytic cells is sensitive to 2-aminopurine."
01/01/1982 - "The survival of UV-irradiated lambda phages is increased when host bacteria are grown in the presence of the base analogue 2-aminopurine (2AP) before infection. "
03/01/1989 - "In addition, we show that viral infection coinduces the expression of TNF-alpha and interferon beta mRNA and that viral induction of both genes is blocked by the kinase inhibitor 2-aminopurine. "
05/01/2009 - "Inhibition of RNA-activated protein kinase (PKR) by 2-aminopurine completely abolished both BAFF mRNA and protein production after reovirus-1 infection and poly(I:C) stimulation through NF-kappaB and p38 MAPK pathways, with the latter implicated only after poly(I:C) stimulation. "
12/12/2003 - "The synthesis of the endogenous Hsps induced by the heat shock to test for thermotolerance is also blocked by 2-aminopurine. "
07/01/1988 - "Two other inducible systems, representing genes involved in interferon action (both its development and activation), and those of heat shock, were not affected by 2-aminopurine. "
01/01/1993 - "The expression of both c-fos following X/XOD treatment and hsp70 following heat shock was markedly decreased through chelation of [Ca2+]i by Quin 2/AM. The c-fos expression following X/XOD treatment was partly reduced by a protein kinase C inhibitor, staurosporine (ST), and markedly inhibited by another protein kinase inhibitor, 2-aminopurine (2AP), while both ST and 2AP markedly reduced hsp70 expression. "
|5.||Ganglion Cysts (Ganglion)
08/01/1997 - "The protein kinase inhibitor 2-aminopurine (2-AP, 10 mM) prevented apoptosis of axotomized ganglion cells and induced apoptosis in the NBL. "
10/01/2006 - "We have previously shown that anisomycin, a protein synthesis inhibitor, and 2-aminopurine, a specific inhibitor of the double stranded-RNA dependent protein kinase, block apoptosis of ganglion cells induced by axotomy, and induce apoptosis of cells in the neuroblastic layer in developing rat retina. "
|2.||Messenger RNA (mRNA)
|3.||Protein Kinases (Protein Kinase)
|6.||Staphylococcal Protein A (A, Protein)
|7.||RNA (Ribonucleic Acid)
|9.||p38 Mitogen-Activated Protein Kinases
|10.||Protein Kinase Inhibitors