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2-Acetylaminofluorene (2 Acetylaminofluorene)

A hepatic carcinogen whose mechanism of activation involves N-hydroxylation to the aryl hydroxamic acid followed by enzymatic sulfonation to sulfoxyfluorenylacetamide. It is used to study the carcinogenicity and mutagenicity of aromatic amines.
Also Known As:
2 Acetylaminofluorene; 2-AAF; 2-Fluorenylacetamide; Acetylaminofluorene; N-2-Fluorenylacetamide; 2 Acetamidofluorene; 2 Fluorenylacetamide; Fluoren 2 ylacetamide; N 2 Fluorenylacetamide; 2-Acetamidofluorene; Fluoren-2-ylacetamide; Acetamide, N-9H-fluoren-2-yl-
Networked: 361 relevant articles (6 outcomes, 33 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Sultana, Sarwat: 6 articles (09/2015 - 01/2006)
2. Yao, Deng-Fu: 5 articles (09/2013 - 12/2007)
3. Yao, Min: 4 articles (06/2014 - 04/2010)
4. Wu, Wei: 4 articles (06/2011 - 12/2007)
5. Qiu, Li-Wei: 4 articles (06/2011 - 12/2007)
6. van Steeg, H: 3 articles (04/2011 - 01/2001)
7. de Vries, Annemieke: 3 articles (08/2007 - 08/2004)
8. Hoogervorst, Esther M: 3 articles (08/2007 - 08/2004)
9. van Steeg, Harry: 3 articles (08/2007 - 08/2004)
10. Hasan, Syed Kazim: 2 articles (09/2015 - 07/2013)

Related Diseases

1. Neoplasms (Cancer)
2. Hepatocellular Carcinoma (Hepatoma)
3. Liver Neoplasms (Liver Cancer)
4. Body Weight (Weight, Body)
5. Urinary Bladder Neoplasms (Bladder Cancer)

Related Drugs and Biologics

1. Diethylnitrosamine (N-Nitrosodiethylamine)
2. Proliferating Cell Nuclear Antigen (PCNA)
3. Diosmin (Daflon)
4. Carboxymethylcellulose Sodium (Polycell)
5. Carcinogens
6. Methylcholanthrene
7. Aflatoxins
8. Caffeine (No Doz)
9. anthracene
10. methylazoxymethanol

Related Therapies and Procedures

1. Intraperitoneal Injections
2. Hepatectomy
3. Oral Administration
4. Aftercare (After-Treatment)
5. Subcutaneous Injections