1-Carboxyglutamic Acid (1 Carboxyglutamic Acid)

Subscribe to Selected New Research on 1-Carboxyglutamic Acid

67 relevant articles (0 outcomes, 3 trials/studies) found for this Bio-Agent

Description: Found in various tissues, particularly in four blood-clotting proteins including prothrombin, in kidney protein, in bone protein, and in the protein present in various ectopic calcifications.

Also Known As:

1 Carboxyglutamic Acid; gamma Carboxyglutamic Acid; 3-Amino-1,1,3-propanetricarboxylic Acid; gamma Carboxyglutamate; gamma-Carboxyglutamate; gamma-Carboxyglutamic Acid; 1,1,3-Propanetricarboxylic acid, 3-amino-

Bio-Agent Context: Research Results

Organic Chemicals: 40

Carboxylic Acids: 63

Acyclic Acids

Tricarboxylic Acids: 3

1-Carboxyglutamic Acid: 67

gamma-glutamyl-3-carboxy-4-nitroanilide

N-carbobenzoxy-(gamma,gamma'-di-tert-butyl)-gamma-carboxyglutamylglycine ethyl ester

n-heptafluorobutyryl isobutyl ester of gamma-carboxyglutamic acid

Amino Acids, Peptides, and Proteins

Amino Acids: 8523

Acidic Amino Acids: 33

Glutamic Acid: 7419

1-Carboxyglutamic Acid: 67

gamma-glutamyl-3-carboxy-4-nitroanilide

N-carbobenzoxy-(gamma,gamma'-di-tert-butyl)-gamma-carboxyglutamylglycine ethyl ester

n-heptafluorobutyryl isobutyl ester of gamma-carboxyglutamic acid

Dicarboxylic Amino Acids: 20

Glutamic Acid: 7419

1-Carboxyglutamic Acid: 67

gamma-glutamyl-3-carboxy-4-nitroanilide

N-carbobenzoxy-(gamma,gamma'-di-tert-butyl)-gamma-carboxyglutamylglycine ethyl ester

n-heptafluorobutyryl isobutyl ester of gamma-carboxyglutamic acid

Experts

1.	Morita, Takashi: 1 article (04/2002)
2.	Kohgo, Yutaka: 1 article (04/2002)
3.	Fujimoto, Yoshinori: 1 article (04/2002)
4.	Ohhira, Motoyuki: 1 article (04/2002)
5.	Saito, Hiroyuki: 1 article (04/2002)
6.	Naraki, Toru: 1 article (04/2002)
7.	Kohno, Noriatsu: 1 article (04/2002)

Related Diseases

1.	Bone Resorption 01/01/1991 - "Serum-free gamma carboxyglutamic acid (free Gla) is a poor biochemical marker of bone resorption in early postmenopausal women." 12/01/2004 - "3. Among the 67 women who completed the study (24 on ISO, 24 on V, 19 on P), only ISO tablets were proven to decrease significantly urinary deoxypyridinoline (Dpd) excretion (P < 0.05 vs before), a specific biomarker of bone resorption, but there was no significant difference in serum bone gamma-carboxyglutamic acid-containing protein (BGP), a specific serum biomarker of bone formation" 06/01/1985 - "The variables investigated were distal forearm bone mineral content (BMC), biochemical markers of bone formation: serum alkaline phosphatase and serum bone gamma-carboxyglutamic acid containing protein (BGP) and biochemical markers of bone resorption: fasting urinary calcium and fasting urinary hydroxyproline" 02/01/2007 - "Serum bone-specific alkaline phosphatase as well as the urinary markers of bone resorption (N-telopeptide cross-links of collagen, pyridinoline and deoxypyridinoline) and urinary gamma-carboxyglutamate were unaffected by phylloquinone supplementation" Get all the results and reference details, order at left...
2.	Urinary Calculi (Urinary Calculus) 12/01/1985 - "Study on the causative factor producing urinary calcium stones--urinary excretion of gamma-carboxyglutamic acid under various conditions]" Get all the results and reference details, order at left...
3.	Osteoporosis 12/01/1983 - "Urinary gamma-carboxyglutamic acid and serum osteocalcin as bone markers: studies in osteoporosis and Paget's disease." Get all the results and reference details, order at left...
4.	Vitamin K Deficiency 09/01/1989 - "Effect of vitamin K deficiency on urinary gamma-carboxyglutamic acid excretion in rats." 12/01/1988 - "After two weeks, vitamin K deficiency was established in the experimental group as shown by decreased urinary excretion of gamma-carboxyglutamic acid and an elevation of serum prothrombin times to between two to two and one-half times the control values" 04/01/1985 - "The assay system developed may be useful for the detection of vitamin K deficiency, since a severe deficiency may result in less gamma-carboxyglutamic acid residues in the protein." 03/01/1985 - "Vitamin K deficiency results in the appearance of abnormal prothrombin, deficient in gamma-carboxyglutamic acid, in the blood" 12/01/1980 - "Vitamin K and bone metabolism - on the effect of vitamin K deficiency and gamma-carboxyglutamic acid (author's transl)]" Get all the results and reference details, order at left...
5.	Neoplasms (Cancer) 02/01/2001 - "Growing evidence suggests that most normal and tumor cells possess an active K1-dependent gamma-carboxylation mechanism necessary for the production of gamma-carboxyglutamic acid (Gla)-containing proteins" 03/01/1993 - "Immunoreactivity for osteocalcin (human bone gamma-carboxyglutamic acid-containing protein) was demonstrated in most of these tumor cells" 11/16/1982 - "Vitamin K dependent formation of gamma-carboxyglutamate residues in tumor microsomes." 11/01/1980 - "PTH responsiveness correlated with several properties, presumably associated with the osteoblastic phenotype: elevated alkaline phosphatase activity, synthesis of the gamma-carboxyglutamic acid-containing bone protein, and production of mineralized tumors in host rats" 02/01/1984 - "It is suggested that this case of 'neoplasm-induced post-traumatic myositis ossificans' may be caused by the interaction of local haemorrhage and thrombosis, mucin-producing tumour implants, and the presence of large quantities of gamma-carboxyglutamic acid, an amino acid associated with the calcification of bone matrix formation." Get all the results and reference details, order at left...
48 Diseases and 67 more articles analyzed in the Research Interface, order at left...

Related Drugs and Biologics

1.	Osteocalcin
2.	Calcium
3.	deoxypyridinoline
4.	Tablets
5.	Vitamin K
6.	Proteins (Proteins, Gene)
7.	Prothrombin (Factor II)
8.	Protein C
9.	Alkaline Phosphatase
10.	acarboxyprothrombin (DCP)
49 Drugs and Important Bio-Agents and 59 more articles analyzed in the Research Interface, order at left...

Related Therapies and Procedures

1.	Pancreas Transplantation
2.	Renal Dialysis (Hemodialysis)
2 Therapies and Procedures and 2 more articles analyzed in the Research Interface, order at left...

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