Zoonoses

Diseases of non-human animals that may be transmitted to HUMANS or may be transmitted from humans to non-human animals.

Also Known As:

Zoonotic Diseases; Zoonotic Infections; Zoonotic Infectious Diseases; Disease, Zoonotic; Disease, Zoonotic Infectious; Diseases, Zoonotic; Diseases, Zoonotic Infectious; Infection, Zoonotic; Infections, Zoonotic; Infectious Disease, Zoonotic; Infectious Diseases, Zoonotic; Spillovers, Zoonotic; Zoonotic Disease; Zoonotic Infection; Zoonotic Infectious Disease; Zoonotic Spillovers; Zoonotic Spillover

Networked: 778 relevant articles (15 outcomes, 53 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1.	Smallpox (Variola)
2.	Infections
3.	Human Influenza (Influenza)
4.	Fascioliasis
5.	Schistosomiasis (Bilharziasis)

Experts

1.	Bowen, John E: 4 articles (01/2022 - 01/2021)
2.	Cameroni, Elisabetta: 4 articles (01/2022 - 01/2021)
3.	Corti, Davide: 4 articles (01/2022 - 01/2021)
4.	Culap, Katja: 4 articles (01/2022 - 01/2021)
5.	Czudnochowski, Nadine: 4 articles (01/2022 - 01/2021)
6.	De Marco, Anna: 4 articles (01/2022 - 01/2021)
7.	Havenar-Daughton, Colin: 4 articles (01/2022 - 01/2021)
8.	Kaiser, Hannah: 4 articles (01/2022 - 01/2021)
9.	Pinto, Dora: 4 articles (01/2022 - 01/2021)
10.	Pizzuto, Matteo Samuele: 4 articles (01/2022 - 01/2021)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Zoonoses:

1.	VaccinesIBA 11/01/2014 - "Canine leishmaniosis (CanL) is an important zoonotic disease; however, the efficacy of available vaccines for the prevention of naturally-occurring Leishmania infantum (L. " 07/12/2001 - "A prioritised list of research requirements is suggested: (i) new drugs; (ii) resistance management; (iii) vaccines; (iv) breeding for resistance; (v) improved diagnostics; (vi) zoonoses; (vii) global warming and parasites. " 03/26/2018 - "Therefore, increasing the standard of care potentially offered by T cell vaccines should be considered in the context of pandemic preparedness and zoonotic infections, and in combination with improved antibody vaccine targeting methods. " 06/24/2022 - "Our exploratory study supports further improvement of the RBD-based vaccine to prevent zoonotic spillover of MERS-CoV." 01/01/2020 - "Although, several studies have been conducted for better understanding of these viruses` evolution, and designing the effective anti-viral drugs and vaccines, the impact of human beings on occurrence of zoonotic diseases has been less considered and discussed. "
2.	Neutralizing AntibodiesIBA 01/01/2019 - "[Zoonotic infection with simian foamy viruses: potent neutralizing antibodies]." 10/01/2016 - "VVIHD-J neutralizing antibodies in sera from the protected mice suggest that the prime/boost vaccination regimen with 4DNAmix plus 4FPmix may be an effective and safe mode to induce protection against smallpox and poxvirus zoonotic infections. " 11/20/2009 - "It is increasingly clear that influenza A infection induces cross-subtype neutralizing antibodies that may potentially confer protection against zoonotic infections. "
3.	AntigensIBA 01/01/1978 - "Immunodiagnosis of parasitic zoonoses: comparative efficacy of three immunofluorescence tests using antigens purified by affinity chromatography." 01/01/2018 - "GALT is a highly conserved antigen in gram-negative bacteria, and has been shown to play a crucial role in the pathogenesis of many zoonoses. " 09/01/2010 - "The parasite antigen was present as a zoonotic infection in Ahvaz district, South-west of Iran. " 08/01/2003 - "Diagnosis of parasitic zoonoses by immunoenzymatic assays--analysis of cross-reactivity among the excretory/secretory antigens of Fasciola hepatica, Toxocara canis, and Ascaris suum." 04/01/1983 - "Immunodiagnosis of parasitic zoonoses: purification of Toxocara canis antigens by affinity chromatography."
4.	Drinking WaterIBA 05/01/2009 - "The paper also explores the potential of improved farm and catchment scale management to deliver cost-effective mitigation of pollution of bathing and drinking water by livestock zoonoses." 01/01/2010 - "jejuni are zoonotic infections that are acquired from exposure to tainted food (undercooked hamburger and chicken, respectively) and contaminated drinking water. " 10/01/2005 - "The increasing world population and the inability to keep pace with the provision of adequate sanitation and clean, safe drinking water, has led to an increased importance of waterborne zoonoses, such as those caused by Giardia, Cryptosporidium and Toxoplasma. " 07/01/2004 - "[Parasitic zoonoses transmitted by drinking water. " 08/01/2000 - "[Parasitic zoonotic disease agents in human and animal drinking water]."
5.	Biological Warfare AgentsIBA 11/01/2020 - "The increasing need to manage biosecurity threats, such as diseases, zoonoses, and biological weapons, poses serious challenges for risk analysts and policymakers. " 01/01/2012 - "Orthopoxviruses remain a threat as biological weapons and zoonoses. " 07/01/2011 - "We still face a threat of orthopoxviruses in the form of biological weapons and emerging zoonoses. " 09/15/2008 - "Practically all potential bioterrorism agents are zoonoses, and it is cost-effective to control them at the veterinary level, providing the first line of defense. " 02/01/2011 - "Although smallpox has been eliminated from the environment, treatments are urgently being sought due to the risk of smallpox being used as a bioterrorism agent and for monkeypox virus, a zoonotic disease of Africa, and adverse reactions to smallpox virus vaccinations. "
6.	Peptides (Polypeptides)IBA 07/15/2023 - "In this scenario, it is worth highlighting a group of natural peptide molecules (AMPs and CPPs) that are promising strategies for improving therapeutic efficacy against these neglected zoonoses, as they avoid the development of toxicity and resistance of conventional treatments. " 11/01/2015 - "Antibacterial peptide compound from Xenorhabdus budapestensis exert marked antibacterial effect on zoonotic patogen bacteria and they should be further evaluated in future for their potential use in the control or prevention of zoonoses." 11/01/2014 - "We can demonstrate that the highly conserved orthopoxvirus surface protein D8 is the interaction partner of αVACVpep05, thus enabling the peptide to bind to other orthopoxviruses, including cowpox virus and monkeypox virus, viruses that cause clinically relevant zoonotic infections in humans. " 01/08/2010 - "Accordingly, protein sequences from influenza A virus strains currently in circulation (H1N1, H3N2), agents of past pandemics (H1N1, H2N2, H3N2) and zoonotic infections of man (H1N1, H5N1, H7N2, H7N3, H7N7, H9N2) were evaluated for the presence of amino acid sequences, motifs, that are predicted to mediate peptide epitope binding with high affinity to the most frequent HLA-DR allelic products. "
7.	mRNA VaccinesIBA 05/04/2021 - "There have been rapid developments in safe and effective mRNA vaccines for zoonotic infections in the past year. " 01/01/2022 - "mRNA Vaccine Development for Emerging Animal and Zoonotic Diseases." 05/04/2021 - "Also, mRNA vaccines are in development for several other potential pandemic zoonotic infections, including Ebola virus, rabies virus, Zika virus, HIV-1, and influenza. "
8.	Influenza Vaccines (Influenza Vaccine)FDA Link 01/01/2018 - "The development of influenza vaccines that can provide broad protection against all drifted seasonal virus variants, zoonotic infections and emerging pandemic strains, has been a priority for two decades. "
9.	Food Additives (Food Additive)IBA 01/01/2008 - "Other issues and challenges include food additives and chemical residues, animal identification and traceability issues, the safety and quality of organic and natural products, the need for and development of improved and rapid testing and pathogen detection methodologies for laboratory and field use, regulatory and inspection harmonization issues at the national and international level, determination of responsibilities for zoonotic diseases between animal health and regulatory public health agencies, establishment of risk assessment based food safety objectives, and complete and routine implementation of HACCP at the production and processing level on the basis of food handler training and consumer education. "
10.	BenzenesulfonamidesIBA 01/01/2023 - "Clorsulon is a benzenesulfonamide drug that is effective in treating helminthic zoonoses such as fascioliasis. "

Therapies and Procedures

1.	Heterologous Transplantation (Xenotransplantation) 07/01/2015 - "This includes their potential use as organ donors in xenotransplantation but also studies on various zoonotic infections affecting pigs and humans. " 01/01/2020 - "However, one of the unique ethical challenges faced by xenotransplantation is that the risk of introducing potential zoonotic disease into the community must be weighed along with the benefit to the patient. " 01/01/2017 - "Understanding interactions between PERV-A and its cellular receptor may provide novel strategies to prevent zoonotic infection in the setting of xenotransplantation." 10/01/2015 - "International travel for xenotransplantation procedures can facilitate transmission of zoonotic disease." 10/01/2015 - "The PERV-A/C recombinant virus can infect human cells and is a major risk of zoonotic disease in the case of xenotransplantation of pig organs to humans. "
2.	Personal Protective Equipment 07/01/2019 - "The objectives of this study were to estimate: (a) the frequency of zoonoses in large animal veterinarians from rural areas of the province of Buenos Aires, Argentina, and (b) to describe the use and disposal of personal protective equipment (PPE) and selective veterinary clinical waste. " 10/01/2022 - "Further, appropriate personal protective equipment should be used when handling beavers, to prevent zoonotic infection with Giardia spp." 05/01/2022 - "When dealing with an animal suspected of carrying a zoonotic infection, nearly 25% of experts isolate or quarantine diseased animals, and only about 25% of the experts remove their personal protective equipment (PPE) before interacting with other animals. " 01/01/2022 - "To understand large animal veterinarians' knowledge of select zoonotic diseases that cause livestock abortions and identify barriers to using personal protective equipment (PPE). " 01/01/2022 - "The strategies encompassed personal protective equipment (PPE), zoonotic disease awareness, policies and protocols, supportive environments, and leadership. "
3.	Transplantation 01/01/2023 - "The rat and mice pancreas are not of an accurate size for transplantation but can only be used for in-vitro studies mimicking in-vivo immune response in humans, while the porcine pancreas can cause zoonotic diseases as it carries porcine endogenous retrovirus (PERV- A/B/C). " 01/01/2023 - "In this document, we review the currently available evidence regarding the epidemiology of zoonotic infections in patients undergoing transplantation, focusing on pediatric patients from a risk-benefit perspective, to help inform decision-making for clinicians. " 12/01/2018 - "However, cross-species transplantation and immunosuppression raises concerns about transmission of zoonotic infections to the recipient as well as to the public. " 03/15/2007 - "Documented zoonotic infection as it affects transplantation will be the primary focus of this review." 01/01/1995 - "Not only are the immunological barriers to the acceptance of xenogeneic tissue more powerful than those seen in allotransplantation, but the potential for the transmission of xenograft-associated zoonoses to the human host at the time of transplantation is also present. "
4.	Cell- and Tissue-Based Therapy (Cell Therapy) 04/01/2013 - "This finding gives us a hope for future cell therapy studies and trials with little concern about zoonotic infections or immunological reaction." 04/01/2013 - "But FBS containing culturing media may raise the possibility of zoonotic infections and immunological reactions in cell therapy conditions. " 10/02/2015 - "Clinicians should be aware of health risks, such as Q fever and other zoonotic diseases, among patients with a history of receiving treatment with live cell therapy products." 10/01/2015 - "Clinicians should consider zoonotic diseases, such as Q fever, in patients whose history includes receipt of a treatment known as live cell therapy. " 01/01/2015 - "Mesenchymal stem cells (MSCs) cultured with medium containing FCS or FBS are unusable in the cell therapy; in fact the central issues regarding limitations in using animal sera for cell therapy is that its components are highly variable and often unknown and may trigger a xenogenic immune response, immunological reactions, and the potential transmission of prion diseases and zoonoses. "
5.	Organ Transplantation 06/01/1994 - "A practical study of zoonoses that could complicate pig-to-man organ transplantation." 10/01/2004 - "The SARS outbreak has demonstrated the vulnerability of an organ transplantation service and reminds us of the fearful possibility of zoonoses in future xeno-transplantation." 01/01/1998 - "The discussion about the clinical risk of zoonoses in xenotransplantation has recently culminated in the demand for a moratorium on clinical organ transplantation using pig donors. "