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Werner Syndrome (Werner's Syndrome)

An autosomal recessive disorder that causes premature aging in adults, characterized by sclerodermal skin changes, cataracts, subcutaneous calcification, muscular atrophy, a tendency to diabetes mellitus, aged appearance of the face, baldness, and a high incidence of neoplastic disease.
Also Known As:
Werner's Syndrome; Adult Progeria; Syndrome, Werner; Syndrome, Werner's; Werners Syndrome; Progeria, Adult
Networked: 567 relevant articles (11 outcomes, 35 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Insulin Resistance
2. Neoplasms (Cancer)
3. Chromosome Aberrations (Chromosome Abnormalities)
4. Progeria (Hutchinson Gilford Syndrome)
5. Atherosclerosis

Experts

1. Bohr, Vilhelm A: 34 articles (01/2014 - 08/2002)
2. Lebel, Michel: 16 articles (12/2015 - 01/2002)
3. Kipling, David: 16 articles (01/2015 - 04/2003)
4. Davis, Terence: 16 articles (01/2015 - 04/2003)
5. Opresko, Patricia L: 15 articles (11/2011 - 06/2003)
6. Brosh, Robert M: 12 articles (10/2013 - 06/2002)
7. Yokote, Koutaro: 11 articles (06/2015 - 09/2004)
8. Bagley, Mark C: 11 articles (01/2015 - 11/2006)
9. Goto, Makoto: 11 articles (12/2014 - 03/2003)
10. Enomoto, Takemi: 11 articles (09/2014 - 08/2002)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Werner Syndrome:
1. DNA (Deoxyribonucleic Acid)IBA
2. EnzymesIBA
3. Phosphotransferases (Kinase)IBA
4. Adenosine Triphosphate (ATP)IBA
5. troglitazone (Rezulin)FDA Link
6. VX-745IBA
7. 2,4-thiazolidinedione (thiazolidinedione)IBA
8. RNA (Ribonucleic Acid)IBA
9. OxygenIBA
10. Nonsense Codon (Nonsense Mutation)IBA

Therapies and Procedures

1. Penetrating Keratoplasty
2. Aftercare (After-Treatment)
3. Lasers (Laser)
4. Phacoemulsification
5. Caloric Restriction