|1.||Tapon, Nicolas: 12 articles (11/2015 - 08/2002)|
|2.||Gao, Xing-Hua: 11 articles (07/2015 - 04/2005)|
|3.||Harvey, Kieran F: 10 articles (12/2015 - 08/2002)|
|4.||Chen, Hong-Duo: 10 articles (07/2015 - 04/2005)|
|5.||Tyring, Stephen K: 9 articles (01/2015 - 04/2002)|
|6.||Irvine, Kenneth D: 9 articles (01/2015 - 10/2006)|
|7.||Huo, Wei: 7 articles (07/2015 - 09/2009)|
|8.||Hong, Yuxiao: 7 articles (07/2015 - 05/2009)|
|9.||Stockfleth, E: 7 articles (03/2010 - 11/2000)|
|10.||Stockfleth, Eggert: 6 articles (06/2012 - 10/2007)|
|1.||imiquimod (Aldara)FDA LinkGeneric
10/01/2002 - "Published studies indicate that imiquimod results in complete clearance of warts in more than 50% of patients. "
01/01/2001 - "In three trials complete clearance of warts at the end of treatment plus no recurrence occurred in 37% of patients treated with imiquimod 5% cream and 4% of those treated with placebo. "
01/01/2001 - "In five trials with HIV-negative patients complete clearance of warts at the end of treatment occurred in 51% of patients treated with imiquimod 2% or 5% cream and 6% of placebo treated patients. "
03/01/1998 - "Phase III trials of imiquimod have demonstrated that patients who experience complete clearance of either new or recalcitrant warts tend to remain clear, possibly related to Th1 immune recognition and memory. "
01/01/2011 - "For placebo, imiquimod 2.5% and 3.75%, respectively, complete clearance of all warts was achieved in 14.2%, 28.3%, and 36.6% of women (intent-to-treat, P = 0.008 imiquimod 2.5%, and P < 0.001 3.75% versus placebo). "
|2.||Bleomycin (Blenoxane)FDA LinkGeneric
11/01/2012 - "Despite the numerous available possibilities for treatment, intralesional bleomycin appears to be the most effective treatment for periungual warts."
07/01/1983 - "Bleomycin is highly efficacious in the treatment of recalcitrant warts, is convenient, and has high patient acceptance. "
07/01/2012 - "Translesional injection by very low-concentration (0.1 U/mL) bleomycin appears to be a simple, effective, and safe treatment modality for plantar warts."
01/01/2006 - "This study assesses therapeutic efficacy of bleomycin delivered by dermojet in solely recalcitrant plantar warts. "
01/01/2002 - "Bleomycin has been shown to be effective in treating warts, but administration can be difficult with risk of local complications. "
|3.||Podophyllotoxin (Condylox)FDA LinkGeneric
08/01/2003 - "When subjects defaulting from follow up were assumed not to have been cured odds of remission of all warts were significantly increased for podophyllotoxin solution (OR 1.92, 95% CI 1.13 to 3.27), but not for podophyllotoxin cream (OR 1.17, 95% CI 0.69 to 2.00). "
08/01/2003 - "When subjects defaulting from follow up were assumed to have been cured odds of remission of all warts were also significantly increased both for podophyllotoxin solution (OR 3.04, 95% CI 1.68 to 5.49) and for podophyllotoxin cream (OR 2.46, 95% CI 1.38 to 4.40). "
04/01/1994 - "When analysing the debulking potential of podophyllotoxin, it appeared that 0.25% podophyllotoxin eradicated 184 of originally 217 warts (85%); the corresponding figure for 0.50% podophyllotoxin was as high as 130 of 135 lesions (96%). "
05/01/1990 - "Podofilox 0.5% solution is effective in treating penile warts and is well tolerated in a self-administered regimen. "
01/01/1998 - "To determine the safety and efficacy of a new gel formulation of podofilox in the treatment of anogenital warts. "
12/01/1994 - "At the dose and with the regime described treatment with IFN alpha-2a in combination with podophyllin is no more effective in the treatment of primary anogenital warts than podophyllin alone and is associated with more adverse events."
01/01/1996 - "After 1 year all the cured cases (100%) that completed follow up had recurrence of warts with podophyllin treatment, while none had recurrence of lesions in the autoimplantation group. "
01/01/1996 - "In the podophyllin group, 70% of patients were cured after 6 weeks while in autoimplantation, only 44% of patients were cured, and none in the control group had natural remission of warts without any treatment. "
11/01/1992 - "A wide range of treatments were used; podophyllin was the commonest first line treatment of multiple penile (60.3%), perianal (57.7%) and vulval (61.5%) warts. "
10/01/1989 - "In contrast, five of 15 patients whose warts were cleared by podophyllin had recurrent warts at 18 weeks and a further four at 42 weeks representing a cumulative recurrence rate of 60 per cent (X2 = 3.95, d.f. "
03/01/2009 - "The patient achieved complete clearance of all warts within 1 month following treatment of his hands with intralesional Candida antigen. "
09/01/2013 - "To examine if Candida antigen resulted in clearance of medically refractory, long-standing common warts in a series of HIV patients. "
05/01/2004 - "Seventy-one percent of subjects had resolution of their warts with the injection of the combination of skin test antigens in this open label single arm study."
07/01/1984 - "Papillomavirus antigen in verruca, benign papillomatous lesions, trichilemmoma, and bowenoid papulosis: an immunoperoxidase study."
10/01/2014 - "Intralesional antigen therapy has been used in the treatment of anogenital warts (AGWs), but it has not been compared with existing therapies. "
11/01/2007 - "Some studies have reported good efficacy when using PDT to treat viral warts in the Western population. "
04/01/2005 - "After combined therapy (PDT + PDL) of 86 warts in 24 patients, 100% were cured, with an average of 1.96 therapeutic sessions. "
01/01/2002 - "The efficacy of topical ALA-PDT in the treatment of recalcitrant foot and hand warts has been shown in a placebo-controlled, randomized, double-blind trial. "
11/01/2013 - "To compare the efficacy of a single treatment with AFXL-assisted PDT vs. AFXL alone for difficult-to-treat AKs and wart-like lesions (WLLs) in OTRs. "
01/01/2004 - "First prospective randomised controlled blind study including PDT and wIRA in the treatment of recalcitrant common hand and foot warts. "
|7.||Salicylic Acid (2 Hydroxybenzoic Acid)FDA LinkGeneric
12/15/2012 - "It is a more effective cure for common warts than salicylic acid or observation. "
01/01/2012 - " of salicylic acid (SA) versus placebo showed that the former significantly increased the chance of clearance of warts at all sites (RR (risk ratio) 1.56, 95% CI (confidence interval) 1.20 to 2.03). "
01/01/1989 - "A clinical study was conducted to evaluate the efficacy of a new delivery system for administering salicylic acid for the treatment of verruca vulgaris. "
10/01/2014 - "as a method of ITM, versus salicylic acid in treatment of wart. "
10/01/2014 - "Versus Salicylic Acid for Wart Treatment."
|8.||Cimetidine (Biomet)FDA LinkGeneric
09/01/2003 - "As a result, 34.5% (19/55) of the patients had a dramatic clinical improvement or complete remission (CR) of their viral warts and 23.6% (13/55) of the patients had partial responses (PR) within 4 months of cimetidine therapy. "
06/01/1996 - "An open-label study was conducted to determine the safety and efficacy of high-dose cimetidine in 20 adult patients with recalcitrant warts. "
12/05/1999 - "High dose cimetidine is known to have immunomodulatory side effects and has been reported as a useful treatment for cutaneous warts. "
04/01/1997 - "Is cimetidine effective for nongenital warts: a double-blind, placebo-controlled study."
06/01/1996 - "A recent study showed cimetidine to be effective in the treatment of multiple warts in children. "
04/01/2013 - "A systematic literature search revealed very minimal, if any, good-quality clinical studies that compare the efficacy of hyfrecation against other treatments (i.e., liquid nitrogen) in treating recalcitrant nongenital warts. "
10/01/2001 - "To compare the efficacy of the traditional freeze and a sustained 10-s freeze in the treatment of common viral warts with liquid nitrogen. "
01/01/1984 - "Of a total of 27 patients treated vigorously with liquid nitrogen, for periods of time ranging from 2 to 34 weeks, only 11 were completely cleared of their warts at the end of the study. "
12/01/2007 - "An in vitro study comparing temperatures of over-the-counter wart preparations with liquid nitrogen."
05/01/1992 - "The author reports on a study of the liquid nitrogen treatment of warts at the Rutgers University Student Health Center. "
|10.||Fluorouracil (Carac)FDA LinkGeneric
06/01/2000 - "In conclusion, the clinical results of the study demonstrate that 5-fluorouracil (1%) in a vaginal hydrophilic gel is safe, tolerable and significantly more effective than placebo to cure intravaginal warts in women."
05/01/2009 - "Topical 5% 5-fluorouracil is a safe, effective, and well-tolerated treatment for warts in children."
05/01/2008 - "5-Fluorouracil is an antimetabolite that has been known to be effective for the treatment of common warts. "
07/01/2004 - "Fluorouracil has been shown to be effective in treating warts but the method of its delivery directly onto the affected tissue has been of little efficacy. "
06/01/2000 - "Breaking the code revealed that 5-fluorouracil (1%) gel had cured 83.3% patients and 87% intravaginal warts. "
|1.||Cryotherapy (Therapy, Cold)
11/01/1993 - "Complete clearance of warts in patients who received up to six treatments of cryotherapy were observed in 86% of cases and in 70% of patients who received up to six treatments of trichloracetic acid. "
08/01/2009 - "Cryotherapy was administered weekly to the wart over 5 months without any significant improvement. "
04/01/1994 - "This therapy is superior to cryotherapy (CT) in that it is useful for warts on any location, regardless of the number of lesions, and it is good for young children, although the cure rates for CT and GA are almost equal."
07/01/2012 - "Topical CPS is more effective than cryotherapy in the treatment of plantar warts."
01/01/2012 - "Subgroup analysis for different sites, hands (RR 2.67, 95% CI 1.43 to 5.01) and feet (RR 1.29, 95% CI 1.07 to 1.55), suggested it might be more effective for hands than feet.A meta-analysis of cryotherapy versus placebo for warts at all sites favoured neither intervention nor control (RR 1.45, 95% CI 0.65 to 3.23). "
05/01/2012 - "No significant reduction in mean wart area was observed for the 168 Wenzhou protocol compliant subjects who also received VLP immunotherapy. "
10/01/1999 - "Contact immunotherapy has been shown to be effective for warts. "
10/01/1988 - "Contact immunotherapy has been proved effective in the treatment of resistant warts. "
12/01/2014 - "We performed an uncontrolled, open-label study to investigate the efficacy of DPCP immunotherapy for the treatment of cutaneous warts. "
05/01/2012 - "Of 33 protocol compliant Brisbane recipients of placebo immunotherapy, 11 were disease free at two months, and a further 9 demonstrated reduction of > 50% in total wart area. "
|3.||Photochemotherapy (Photodynamic Therapy)
10/01/2009 - "Further, some studies have reported good efficacy when using photodynamic therapy to treat viral warts. "
10/01/2009 - "Photodynamic therapy with topical 5-aminolevulinic acid using the light from a red light-emitting diode has the advantage of non-invasiveness, minimal associated adverse reactions, and production of good results in a significant proportion of cases: therefore, it is an alternative treatment for recalcitrant viral warts."
03/01/2014 - "Is the step-up therapy of topical 5-aminolevulinic acid photodynamic therapy effective and safe for the patients with recalcitrant facial flat wart?"
05/01/1999 - "In conclusion, photodynamic therapy with topical 5-aminolaevulinic acid followed by irradiation with white light is a promising treatment for recalcitrant hand and foot warts."
01/01/2005 - "Photodynamic therapy: new treatment for therapy-resistant plantar warts."
02/01/2007 - "Sixty-four per cent (48/75) of warts in the laser group resolved completely compared with 13% (4/30) in the placebo group (p<0.001). "
11/01/1985 - "Improved laser techniques for the elimination of genital and extragenital warts."
06/01/2015 - "This study aimed to determine the effectiveness of a novel laser treatment modality for recalcitrant hand warts. "
03/01/2009 - "The study was conducted on 200 female patients using the standardized questionnaire filled in by patients under the researcher's supervision immediately before laser wart removal. "
06/01/2015 - "The laser treatment method is novel because each treated wart was aligned at the intersection point of the circles of 3 laser pulses per session. "
01/01/1984 - "All patients entered completed the study and during the trial period the warts of 4 patients receiving intralesional injections were completely cleared. "
09/01/2008 - "In one patient with giant perianal wart, the lesion was reduced to less than 5% of its volume after 10 intralesional injections, which was later electrosurgically excised. "
01/01/1984 - "Topical treatment of warts (multiple intralesional injections) has been shown to yield a high success rate, especially in the case of verrucae vulgares, but less so in the case of verrucae planae juveniles. "
08/01/1967 - "[Intralesional injections of methylmethioninsulfonium chloride in plantar warts]."
09/01/2002 - "The object of this study was to compare the clinical outcomes and safety of Candida albicans intralesional injection immunotherapy (CI) versus conventional wart treatment. "