Vulvar Diseases

10/01/2014 - "Our objective was to evaluate the efficacy of conservative treatment with imiquimod in Paget vulvar disease. "

07/01/1990 - "[Study on the localization of human papillomavirus DNA in the vulvar disease by means of in situ hybridization]."
11/01/1994 - "In addition to standard clinical and laboratory investigations of the whole population, a sample of 15 test cases from the population of 71 women referred with a clinicopathological diagnosis of HPV vulvar disease, and two positive and 21 negative controls were assayed for HPV DNA. "
07/01/1990 - "We investigated human papillomavirus (HPV) DNA of vulvar diseases obtained from 18 cases of condyloma acuminatum, 3 cases of hyperplastic dystrophy without atypia, 4 cases of lichen sclerosus, 4 cases of Bowenoid papulosis, one case of Bowen disease and 8 cases of squamous cell cancer by in situ hybridization with biotinylated HPV 6, 11, 16 and 18 DNA probes. "

03/01/2011 - "Patients aged between 18 and 60 years presenting with provoked vestibulodynia (according to the 2003 International Society for the Study of Vulvar Disease classification) received 50 U of botulinum toxin A bilaterally in the bulbospongiosus muscle under electromyographic monitoring. "

03/27/2012 - "Effect of the human papillomavirus (HPV) quadrivalent vaccine in a subgroup of women with cervical and vulvar disease: retrospective pooled analysis of trial data."

01/01/2012 - "A literature search was performed using PubMed and EMBASE and the search terms 'tacrolimus', 'pimecrolimus' or 'calcineurin inhibitors' and 'lichen sclerosus et atrophicus', 'vulvar lichen sclerosus', 'vulvar dermatoses' or 'vulvar diseases'. "

11/01/2002 - "This review follows the progress of research in angiogenesis in vulvar disease as assessed by a variety of methods, such as in situ hybridisation (ISH), microvessel density measurements (MVD), immunohistochemically-detected angiogenic growth factor expression, including vascular endothelial growth factor (VEGF) and platelet-derived endothelial cell growth factor/thymidine phosphorylase (PD-ECGF/TP), and serum concentrations of VEGF. "

11/01/2002 - "This review follows the progress of research in angiogenesis in vulvar disease as assessed by a variety of methods, such as in situ hybridisation (ISH), microvessel density measurements (MVD), immunohistochemically-detected angiogenic growth factor expression, including vascular endothelial growth factor (VEGF) and platelet-derived endothelial cell growth factor/thymidine phosphorylase (PD-ECGF/TP), and serum concentrations of VEGF. "

09/01/2001 - "Cyclin D1 and pRb are separately involved in the progression of vulvar cancer, and changes in the expression of these proteins may represent an early stage of malignant transformation in vulvar disease."

11/01/2003 - "Tenascin was detectable in inflammatory vulvar disease, preinvasive and invasive vulvar lesions, but not in normal vulvar tissue. "

09/01/2003 - "Photodynamic therapy (PDT), in particular Photodynamic diagnosis (PDD) is a modern, non-invasive technique using photosensitizer like 5-aminolevulinic acid (5-ALA) in detection of the vulvar diseases. "

01/01/1989 - "The subject of this report is a surgical method, CO2 laser, for the treatment of non-invasive vulvar diseases. "
03/01/1985 - "The carbon dioxide laser in the treatment of vulvar disease."
03/01/1985 - "Our review of the current use of the carbon dioxide laser in treating vulvar disease reveals that it holds significant promise in the treatment of vulvar intraepithelial carcinoma, condylomata acuminata, and focal vestibular adenitis. "

05/01/2015 - "Focused ultrasound therapy can also be used effectively to treat cervicitis and vulvar diseases. "

10/01/2014 - "Our objective was to evaluate the efficacy of conservative treatment with imiquimod in Paget vulvar disease. "

01/01/2016 - "The goal of the current study was to analyze the appropriate indications of radiotherapy in Primary invasive Extramammary Paget's vulvar disease because they are still controversial. "
08/01/1997 - "Although literature on vulvar disease notes a benefit of radiation therapy for patients with more than one positive lymph node, radiation therapy was not predictive of survival for patients in this study."
01/01/2023 - "The updated guidelines cover comprehensively diagnosis and referral, staging, pathology, pre-operative investigations, surgical management (local treatment, groin treatment, sentinel lymph node procedure, reconstructive surgery), (chemo)radiotherapy, systemic treatment, treatment of recurrent disease (vulvar, inguinal, pelvic, and distant recurrences), and follow-up. "
01/01/2016 - "Primary extramammary invasive Paget's vulvar disease: what is the standard, what are the challenges and what is the future for radiotherapy?"
01/01/2017 - "The guidelines cover diagnosis and referral, preoperative investigations, surgical management (local treatment, groin treatment including sentinel lymph node procedure, reconstructive surgery), radiation therapy, chemoradiation, systemic treatment, treatment of recurrent disease (vulvar recurrence, groin recurrence, distant metastases), and follow-up."

11/01/2002 - "These studies suggest that further angiogenic research will be important in both the therapy and prognosis of malignant and pre-malignant vulvar disease."
01/01/2000 - "Therapy of squamous vulvar diseases creates main problems in modern gynecology. "
01/01/2000 - "[Use of photodynamic methods in diagnosis and therapy of epithelial vulvar diseases]."
09/01/1993 - "[Current diagnosis and therapy of inflammatory vulvar diseases]."
09/01/1990 - "Three patients (10%) developed new or recurrent vulvar disease and underwent additional therapy. "