|1.||Psoriasis (Pustulosis Palmaris et Plantaris)
|3.||Lichen Planus (Lichen Ruber Planus)
|4.||Atopic Dermatitis (Atopic Eczema)
|5.||Melanoma (Melanoma, Malignant)
|1.||Schallreuter, Karin U: 24 articles (08/2013 - 01/2002)|
|2.||Xu, Aie: 19 articles (12/2015 - 07/2008)|
|3.||Parsad, Davinder: 19 articles (01/2015 - 12/2002)|
|4.||Lotti, Torello: 18 articles (11/2015 - 01/2008)|
|5.||Li, Kai: 16 articles (05/2015 - 03/2009)|
|6.||Gao, Tianwen: 16 articles (01/2015 - 03/2009)|
|7.||Gupta, Somesh: 15 articles (12/2015 - 01/2002)|
|8.||Kanwar, A J: 14 articles (05/2015 - 10/2001)|
|9.||Lim, Henry W: 14 articles (05/2015 - 08/2003)|
|10.||Kemp, E Helen: 14 articles (01/2015 - 04/2002)|
|1.||Tacrolimus (Prograf)FDA LinkGeneric
04/01/2015 - "Our study shows that twice-weekly application of 0.1% tacrolimus ointment is effective in preventing the depigmentation of vitiligo patches that have been previously successfully repigmented."
12/01/2011 - "According to this study, the combination of NB-UVB and tacrolimus ointment (0.1%) is more effective than UV treatment alone in patients with vitiligo. "
05/01/2011 - "Topical tacrolimus is more effective for treatment of vitiligo in patients of skin of color."
01/01/2009 - "Patients with vitiligo for more than 5 years also responded well to tacrolimus ointment. "
04/01/2015 - "We hypothesized that a twice-weekly application of 0.1% tacrolimus ointment might be effective for maintaining repigmentation in therapeutically repigmented lesions of vitiligo patients. "
|2.||calcipotriene (calcipotriol)FDA LinkGeneric
09/01/2001 - "Topical calcipotriol appears to be an effective and well-tolerated treatment for vitiligo and can be safely used in conjunction with PUVA, but controlled studies are necessary to exclude the possibility of spontaneous repigmentation."
05/01/2003 - "Is the combination of calcipotriol and PUVA effective in vitiligo?"
03/01/2002 - "Topical calcipotriol in monotherapy is not an effective treatment of vitiligo."
03/01/2001 - "Calcipotriol is effective in certain keratinization disorders (ichtyoses) as well as in localized sclerodermia and vitiligo, although the effect is less certain for the latter conditions. "
05/01/2006 - "The aim of the present study was to compare the clinical efficacy of NB-UVB and NB-UVB plus topical calcipotriol in the treatment of vitiligo. "
11/01/2002 - "Of the various modalities of therapy available for the treatment of vitiligo, a combination of psoralen + ultraviolet A (PUVA) with autologous epidermal grafting appears to offer the best results. "
08/01/2001 - "The use of psoralen plus broadband UVB is as effective as PUVA in the treatment of vitiligo. "
12/01/2013 - "The present study aims to evaluate the efficacy of psoralen-NBUVB (P-NBUVB) vs. NBUVB in vitiligo. "
05/01/2007 - "Randomized double-blind trial of treatment of vitiligo: efficacy of psoralen-UV-A therapy vs Narrowband-UV-B therapy."
02/01/2013 - "Psoralen and ultraviolet A radiation (PUVA) is a gold standard treatment for vitiligo, however, response is still empirical. "
|4.||pimecrolimus (Elidel)FDA Link
05/01/2013 - "This study suggests that 1% pimecrolimus cream is an effective and well-tolerated treatment for segmental childhood vitiligo."
05/01/2013 - "The aim of this study was to study the therapeutic efficacy and safety of 1% pimecrolimus cream for segmental childhood vitiligo. "
05/01/2013 - "However, questions about the therapeutic efficacy of 1% pimecrolimus cream have remained unanswered regarding segmental vitiligo. "
11/01/2006 - "In this group of adult patients with symmetrical vitiligo, treatment of body lesions (except face) with pimecrolimus cream 1% could not be shown to be effective."
05/01/2009 - "The efficacy of pimecrolimus 1% cream combined with microdermabrasion in the treatment of nonsegmental childhood vitiligo: a randomized placebo-controlled study."
|5.||Adrenal Cortex Hormones (Corticosteroids)IBA
03/01/2003 - "The clinical efficacy of low-dose oral corticosteroids was assessed to minimize the side-effects in actively spreading vitiligo patients. "
03/01/2003 - "The efficacy of low-dose oral corticosteroids in the treatment of vitiligo patient."
07/01/1999 - "The clinical efficacy of low-dose oral corticosteroids was assessed to minimize the side-effects in actively spreading vitiligo patients. "
07/01/1999 - "The efficacy of low-dose oral corticosteroids in the treatment of vitiligo patients."
12/01/1998 - "Among randomized controlled trials on localized vitiligo, the pooled odds ratio vs placebo was significant for topical class 3 corticosteroids (14.32; 95% confidence interval [CI], 2.45-83.72). "
03/01/2007 - "The study suggests that: (1) trichrome vitiligo skin may be an ideal in vivo model for studying the effect of skin melanin content and distribution on skin spectroscopy properties. "
03/01/1998 - "Melanin and melanosome complexes in long standing stable vitiligo--an ultrastructural study."
03/01/2015 - "A histopathological analysis for skin lesions obtained from such patients notably showed basal hypo-pigmentation, melanin incontinence, and remaining melanocytes in most patients which is not relevant in vitiligo vulgaris. "
02/01/2015 - "Our results underscore the important role of melanocytes and melanin in cochlear function, and suggest that the cochlear abnormalities in SV point to the presence of additional nonsegmental pathophysiological events underlying all forms of vitiligo."
11/01/2014 - "In agreement with our clinical experience of worsened vitiligo after PPI treatment, PPIs decreased both melanin content and TYR activity. "
04/01/2013 - "Efficacy of topical calcineurin inhibitors in vitiligo."
04/01/2013 - "Additional studies would further clarify the role of topical calcineurin inhibitors in vitiligo."
05/01/2008 - "Recently, topical calcineurin inhibitors have been introduced in the management of vitiligo, but significant repigmentation is not achieved except on the face. "
05/01/2008 - "Repigmentation of pretibial vitiligo with calcineurin inhibitors under occlusion."
01/01/2007 - "Considering the autoimmune hypothesis of vitiligo pathogenesis, the use of these topical calcineurin inhibitors seems reasonable. "
|8.||Phenylalanine (L-Phenylalanine)FDA Link
10/01/1989 - "The administration of phenylalanine (Phe) combined with UVA exposure was found to be effective in treating vitiligo. "
01/01/1985 - "The administration of phenylalanine (Phe) combined with UVA exposure was found to be effective in vitiligo. "
12/01/1989 - "Phenylalanine plus ultraviolet light: preliminary report of a promising treatment for childhood vitiligo."
01/01/1994 - "In order to evaluate the efficacy of L-phenylalanine (L-Phe) in combination with UVA therapy for vitiligo an open trial (149 patients, 18 months) and a small double-blind trial (32 patients, 6 months) were conducted. "
02/13/1998 - "To substantiate this consideration, FT-Raman spectroscopy was utilised to study in vivo total phenylalanine levels at 1004 cm-1 in involved and uninvolved skin of 23 patients with vitiligo, showing in all cases increased levels of phenylalanine in involved compared to uninvolved skin of the same individual. "
|9.||Folic Acid (Vitamin M)FDA LinkGeneric
07/01/1992 - "In a group of fifteen patients with vitiligo, folic acid levels were below normal in the serum of eleven patients, in the whole blood of five patients, and in the erythrocytes of six patients. "
07/01/1992 - "When compared with the normal population, patients with vitiligo often showed diminished blood levels of folic acid. "
04/01/2010 - "Narrowband ultraviolet B phototherapy influences serum folate levels in patients with vitiligo."
11/01/1997 - "The aim of this 2-year study was to test the hypothesis that folic acid, vitamin B12 and sun exposure could be helpful in treating vitiligo. "
01/01/2012 - "In conclusion, vitamin B12, folate and Hcy levels are not altered in vitiligo and MTHFR gene mutations (C677T and A1298C) do not seem to create susceptibility for vitiligo."
06/01/2006 - "The 308-nm xenon chloride excimer laser is an effective and safe modality for the treatment of vitiligo, with good results achieved in a relatively short duration of time."
04/01/2004 - "Treatment of Vitiligo with 308-nm xenon-chloride excimer laser: therapeutic efficacy of different initial doses according to treatment areas."
06/01/2006 - "The aim of this study was to study the effectiveness of the 308-nm xenon chloride excimer laser in the treatment of vitiligo and to determine factors that favor a good response to treatment. "
12/01/2012 - "Monotherapy for vitiligo using a 308-nm xenon-chloride excimer laser: colorimetric assessment of factors that influence treatment efficacy."
06/01/2012 - "We compared the effects of the 308-nm xenon chloride excimer laser (EL) vs. narrow-band ultraviolet B (NB-UVB) after punch grafting in patients with vitiligo. "
|1.||Phototherapy (Light Therapy)
04/01/2008 - "Phototherapy remains the best treatment of vitiligo type I. In vitiligo type II and III, ethiopathogenic treatments may be efficient, alone or associated with phototherapy."
06/01/2007 - "For generalized vitiligo, phototherapy with UVB radiation is most effective with the fewest side effects; PUVA is the second best choice.Topical"
10/01/2010 - "These results suggest that even acral areas in vitiligo can be markedly improved by phototherapy if it has a recent onset."
06/01/2014 - "NB-UVB phototherapy was associated with a significant reduction in MDA levels and a significant increase in GSH-Px levels, compared with baseline, in patients with vitiligo. "
09/01/2003 - "Treatment with 308 nm MEL for vitiligo may be more effective in obtaining rapid repigmentation than phototherapy with NB UVB. "
01/01/2015 - "Excimer laser treatment significantly improved QoL in vitiligo patients, with improvement observed in five of six DLQI domains. "
10/01/2014 - "Excimer laser treatment significantly improved QoL in vitiligo patients, with improvement observed in five of six DLQI domains. "
10/01/2010 - "Studies have suggested that the combination of the 308-nm excimer laser and various topical treatments is more effective than UV monotherapy in the treatment of vitiligo. "
03/01/2014 - "Recently, a 308-nm excimer laser has been shown to be effective in treating vitiligo. "
08/01/2012 - "Quantitative method for measuring therapeutic efficacy of the 308 nm excimer laser for vitiligo."
|3.||Transplantation (Transplant Recipients)
12/01/2005 - "Patients with stable vitiligo can be helped surgically using transplantation of autologous cultured melanocytes, but there is a need for a culture methodology that is free from xenobiotic agents and for a simple way of delivering cultured melanocytes to the patient to achieve pigmentation with good wound healing. "
04/01/2014 - "Cultured autologous melanocyte transplantation is an effective treatment for stable vitiligo. "
01/01/2011 - "Our results demonstrate that transplantation of autologous melanocytes cultured on AM is a new, simple, and effective treatment for stable vitiligo."
08/01/2011 - "Transplantation of noncultured epidermal suspension is a safe and effective treatment for stable vitiligo in childhood. "
03/01/2011 - "Autologous epidermal transplantation is an easy, safe, and effective option for the treatment of stable vitiligo. "
08/01/1998 - "Vitiligo can be successfully treated with grafts of autologous cultured epidermal cells. "
11/01/2013 - "After 6 months, all of the patients had detectable re-pigmented area of about 2-9 mm. giving the surprising result of the study, hair follicle autograft transplant is an effective treatmentoption in the persistent segmental vitiligo."
10/01/2003 - "Twenty-one patients with different types of vitiligo were admitted to the study and treated with autologous cultured epidermal grafts. "
11/01/2000 - "Thirty-two patients carrying different types of vitiligo were admitted to the study and treated with autologous cultured epidermal grafts. "
05/01/1999 - "The present study, spread over past four decades of experience gathered after operating 8000 stable vitiligo patients, reaffirms the value of thin Thiersch's grafts in treating this disfiguring disease. "
05/01/2007 - "In the treatment of nonsegmental vitiligo, NB-UVB therapy is superior to oral PUVA therapy."
05/01/2007 - "In patients who completed 48 sessions, the improvement in body surface area affected by vitiligo was greater with NB-UVB therapy than with PUVA therapy (P = .007). "
02/01/2012 - "Effect of PUVA therapy on melanocytes and keratinocytes in non-segmental vitiligo: histopathological, immuno-histochemical and ultrastructural study."
09/01/2010 - "Quality of life in patients with vitiligo: a descriptive study on 83 patients attending a PUVA therapy unit in Imam Reza Hospital, Mashad."
03/31/2005 - "The present study examined how Electrodermal Activity (EDA) parameters were affected from vitiligo illness before PUVA therapy and whether any electrophysiological gains acquired from PUVA therapy would influence the progression of the condition itself. "