Vitamin D-Binding Protein
149
relevant articles (2 outcomes,
24 trials/studies)
found for this Bio-Agent
Description:
An alpha-globulin found in the plasma of man and other vertebrates. It is apparently synthesized in the liver and carries vitamin D and its metabolites through the circulation and mediates the response of tissue. It is also known as group-specific component (Gc). Gc subtypes are used to determine specific phenotypes and gene frequencies. These data are employed in the classification of population groups, paternity investigations, and in forensic medicine.
Also Known As:
25-HCC-Binding Protein; 25-Hydroxycholecalciferol-Binding Protein; 25-Hydroxyvitamin D-Binding Protein; Calciferol-Binding Protein; Gc Globulin; Transcalciferin; 25 HCC Binding Protein; 25 Hydroxycholecalciferol Binding Protein; 25 Hydroxyvitamin D Binding Protein; Calciferol Binding Protein; Component Globulin, Group-Specific; Globulin, Gc; Globulin, Group-Specific Component; Globulin, Vitamin D-Binding; Group Specific Component Globulin; Vitamin D Binding Globulin; Vitamin D Binding Protein; Group-Specific Component Globulin; Vitamin D-Binding Globulin
Relationship Network
Bio-Agent Context: Research Results
Experts
Related Diseases
| 1. | Necrosis
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| 2. | Hyperparathyroidism
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| 3. | Chronic Obstructive Pulmonary Disease (COPD)
01/01/2004
- " BACKGROUND: Previous studies of vitamin D binding protein (VDBP, also known as group-specific component, Gc, encoded by the GC gene) have implicated two gene variants, GC*2 and GC*1F, as possible contributors with chronic obstructive pulmonary disease (COPD) protection and susceptibility, respectively" 01/01/2004
- " STUDY OBJECTIVE:s: To determine whether Gc-globulin gene polymorphism plays a role in the development of COPD in the Japanese population, and whether it is associated with the physiologic deterioration in COPD, and its radiologically detectable correlates" 03/01/1998
- " There have been three previous studies in which associations between Gc-globulin phenotypes and COPD have been investigated" 01/01/2007
- " SNPs nearby the SOD3 and vitamin D binding protein genes, candidate genes for COPD, exhibited association to percent predicted phenotypes" 03/01/2006
- " The distribution of alleles and genotypes of vitamin D-binding protein (DBP) gene has been studied in patients with Chronic Obstructive Pulmonary Disease (COPD, n = 298) and healthy individuals (n = 237) from two ethnic groups (Tatars and Russians) living in Republic Bashkortostan"
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| 4. | Osteoporosis
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| 5. | Wounds and Injuries (Trauma)
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| 95 Diseases
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149
more articles analyzed in the Research Interface, order at left...
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