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Vinca Alkaloids

A group of indole-indoline dimers which are ALKALOIDS obtained from the VINCA genus of plants. They inhibit polymerization of TUBULIN into MICROTUBULES thus blocking spindle formation and arresting cells in METAPHASE. They are some of the most useful ANTINEOPLASTIC AGENTS.
Also Known As:
Alkaloids, Vinca
Networked: 337 relevant articles (13 outcomes, 17 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Kavallaris, Maria: 5 articles (12/2008 - 09/2002)
2. Braguer, Diane: 4 articles (12/2014 - 02/2006)
3. Kruczynski, Anna: 4 articles (12/2014 - 01/2002)
4. Fan, Weimin: 3 articles (06/2010 - 03/2004)
5. Sui, Meihua: 3 articles (06/2010 - 03/2004)
6. Correia, John J: 3 articles (08/2008 - 01/2007)
7. Lobert, Sharon: 3 articles (08/2008 - 01/2007)
8. Hadj-Kaddour, Kamel: 2 articles (04/2015 - 02/2015)
9. Cuq, Pierre: 2 articles (04/2015 - 02/2015)
10. Vian, Laurence: 2 articles (04/2015 - 02/2015)

Related Diseases

1. Neoplasms (Cancer)
2. Breast Neoplasms (Breast Cancer)
3. Leukemia
4. Idiopathic Thrombocytopenic Purpura (Thrombocytopenic Purpura, Autoimmune)
5. Hematologic Neoplasms (Hematological Malignancy)

Related Drugs and Biologics

1. Taxoids
2. Anthracyclines
3. Vinblastine (Vinblastine Sulfate)
4. Tubulin
5. Colchicine
6. P-Glycoprotein
7. Doxorubicin (Adriamycin)
8. Cisplatin (Platino)
9. vinflunine
10. Mitoxantrone (Novantrone)

Related Therapies and Procedures

1. Drug Therapy (Chemotherapy)
2. Combination Drug Therapy (Combination Chemotherapy)
3. Heterologous Transplantation (Xenotransplantation)
4. Splenectomy
5. Radiotherapy