|2.||Esophageal and Gastric Varices (Esophageal Varices)
|1.||Davies, A H: 12 articles (12/2015 - 01/2007)|
|2.||Khalil, Raouf A: 11 articles (12/2015 - 02/2007)|
|3.||Goldman, Mitchel P: 11 articles (02/2013 - 01/2002)|
|4.||Belcaro, G: 11 articles (09/2011 - 12/2001)|
|5.||Cesarone, M R: 11 articles (09/2011 - 12/2001)|
|6.||Raffetto, Joseph D: 9 articles (08/2011 - 02/2007)|
|7.||Gough, M J: 9 articles (05/2011 - 05/2007)|
|8.||Rabe, E: 8 articles (03/2015 - 05/2004)|
|9.||Chetter, I C: 8 articles (08/2014 - 02/2006)|
|10.||Moll, F L: 8 articles (08/2011 - 04/2007)|
12/25/2007 - "PTVE with cyanoacrylate is safe and effective for the obliteration of gastroesophageal varices in cirrhotic patients."
11/01/1987 - "Cyanoacrylate is a very useful substance for obliterating large esophagogastric varices. "
12/01/2012 - "Definitive comparisons between TIPS, endoscopic cyanoacrylate, and BRTO will be challenging because the incidence of this type of varix is insufficient for large trials. "
10/01/2014 - "We conclude that cyanoacrylate injection effectively manages ectopic duodenal varices and can be used with a simple application technique."
10/01/2014 - "The varix was injected with 1cc of cyanoacrylate. "
|2.||Somatostatin (Somatotropin Release-Inhibiting Factor)IBA
01/01/1999 - "Through its inhibitory action on acid-peptic secretion, somatostatin may also inhibit peptic digestion of the clot at the site of hemostasis on the varix itself. "
02/01/1988 - "Thus, potential haemostatic benefits of somatostatin cannot be explained by pressure reductions in the varices."
01/01/1979 - "Cyclic somatostatin was administered intravenously on eight occasions to five consecutive patients with massive haemalemesis due to oesophageal varices. "
01/01/1992 - "Furthermore, gastric acid suppression and potential enhancement of platelet aggregation may contribute to the beneficial outcome after treatment of oesophageal varices with somatostatin."
01/01/1987 - "Somatostatin seems to be effective in achieving initial haemostasis in patients with bleeding oesophageal varices. "
|3.||Propranolol (Inderal)FDA LinkGeneric
02/01/1994 - "Propranolol has been shown to be effective in both primary and secondary treatment of variceal haemorrhage; most primary prevention trials have only included patients with large oesophageal varices. "
04/01/2005 - "Both EVL plus propranolol and EVL alone are effective in primary prophylaxis of bleed from high-risk varices. "
03/01/2013 - "The study had the following aims: to study (1) the effect of propranolol on the growth of small varices and (2) whether single or serial HVPG measurements result in a better outcome compared to no measurement in patients with small varices. "
12/01/2005 - "They were injected on a weekly basis until varices were eradicated at which time propranolol was withdrawn. "
02/01/1997 - "He emphasized that recent randomized clinical trials (RCT) have demonstrated that propranolol delays and decreases the occurrence of haemorrhage from varices in patients who have not previously suffered such complications. "
|4.||polidocanol (Laureth)FDA Link
04/10/1990 - "Varices were injected with ethoxysclerol 1% in weekly sessions if possible until they were completely eradicated. "
06/01/2012 - "Efficacy and safety of Aethoxysklerol® (polidocanol) 0.5%, 1% and 3% in comparison with placebo solution for the treatment of varicose veins of the lower extremities in Chinese patients (ESA-China Study)."
12/01/2015 - "Treatment of Truncal Incompetence and Varicose Veins with a Single Administration of a New Polidocanol Endovenous Microfoam Preparation Improves Symptoms and Appearance."
08/03/2015 - "Polidocanol (Varithena) for varicose veins."
10/01/2014 - "Polidocanol endovenous microfoam provided clinically meaningful benefit in treating symptoms and appearance in patients with varicose veins. "
|5.||Octreotide (Sandostatin)FDA LinkGeneric
01/01/1990 - "A study of octreotide in oesophageal varices."
04/01/2007 - "The dosage 50 microg/h of octreotide infusion may be more rational for prevention rebleeding of varices in cirrhotic portal hypertensive patients."
01/01/2006 - "The surface area of the varices did not change significantly after octreotide (mean change, -0.771 mm2) or placebo (mean change, -0.015 mm2) injection. "
01/01/2006 - "In the periesophageal varices, the velocity and flow changes caused by octreotide differed significantly from those caused by the placebo (P < .001). "
09/01/2005 - "The patient was treated medically with octreotide, beta-blockade, and external beam radiation therapy applying the physiology of esophagogastric varices to the small bowel. "
|6.||ethanolamine oleate (Ethamolin)FDA Link
11/01/1999 - "Intravariceal injection using 5% ethanolamine oleate was performed under fluoroscopy until varices were eradicated. "
04/01/1986 - "The results might furthermore serve as a basis for a prospective morphological study of patients with varices treated with ethanolamine oleate."
09/01/2011 - "From 2005 to 2009, we performed BRTO in 20 patients with gastric fundal varices, by intravariceal injection of 5% ethanolamine oleate (EO) as the sclerosant. "
03/01/2007 - "It is likely that, in this patient, the mucosal vessels communicated with the submucosal large varices, and ethanolamine oleate (EOI) flowed into the gastric mucosa via this communication. "
11/01/2005 - "The injection of 5% ethanolamine oleate was continued until it filled the varices and their feeder veins under fluoroscopic guidance. "
09/01/2015 - "In 2 patients besides trials of ligating the varix, histoacryl was put in use which proved success. "
10/01/2014 - "Management of ectopic varix with histoacryl."
04/01/2014 - "Successful treatment of mesenteric varices by retrograde transvenous obliteration by the delivery of N-butyl-2-cyanoacrylate via an abdominal wall vein."
02/01/2014 - "Orbital varices may be recurrent, even after n-butyl cyanoacrylate embolization, with repeated Valsalva-type maneuvers."
02/01/2014 - "Recurrent orbital varices after surgical excision with and without prior embolization with n-butyl cyanoacrylate."
11/01/1979 - "For the initial control of haemorrhage from oesophageal varices, two methods of vasopressin administration have been compared--the conventional bolus of 20 units and a low dose infusion of 0.4 units per minute. "
07/01/1984 - "These results demonstrate that during vasopressin infusion: (a) there is no constriction of the varices at the level of the lower esophageal sphincter; (b) there is a marked decrease in the perfusion of left gastric vein and esophageal varices; and (c) there is a moderate portal pressure decrease which, by itself, may not be a reliable index of the splanchnic hemodynamic response to vasopressin in cirrhotic patients."
11/01/1979 - "Our study confirms that low dose vasopressin infusion in more effective in controlling bleeding from oesophageal varices than conventional bolus doses."
01/01/1980 - "Percutaneous transhepatic embolization of varices (PTEV) has proved to be effective in the control variceal bleeding, particularly in Child's Class C Category patients whose bleeding was not adequately controlled by pitressin perfusions. "
09/01/1979 - "Infusions of intraarterial vasopressin (IAV) into the superior mesenteric artery have been shown to be effective in controlling hemorrhage from esophagogastric varices. "
06/01/2014 - "The true extent of the severity of the disease is hampered because of reduced public awareness, operational difficulties in diagnosis, and the perception that varicose veins are mainly a cosmetic inconvenience. "
03/01/2013 - "Treatment for varicose veins is often not commissioned to at a local level, most likely because it is misperceived to be a cosmetic problem. "
07/01/2011 - "We studied the early cosmetic and functional outcome of this procedure to identify the optimum time gap from SFJLD to multiple stab avulsions for varicose veins (VV). "
10/01/2008 - "It offers the additional advantage of resolving varicose veins and its cause in just one visit, leading to immediate better cosmetic results."
09/01/2008 - "EVLA can reduce and relieve symptoms associated with varicose veins and achieve cosmetic goals. "
|10.||Sclerosing Solutions (Sclerosing Agents)IBA
08/01/1988 - "Trial of sclerosing agents in patients with oesophageal varices."
10/01/1965 - "[Preliminary phlebocinematographic study of sclerosing injections of varices]."
05/01/2004 - "The use of foamed sclerosing agents in therapy of large or small varicose veins is not new. "
10/01/1995 - "The usual method of injection of sclerosing agents is based simply on clinical recognition and visualization of the varicose vein. "
05/01/1994 - "Radical treatment of varicose veins, whether by sclerosing injections or surgery, depends upon the anatomical nature of lesions, the degree of venous incompetence and the extent of signs, but also the wishes of the patient, properly informed of the advantages and limitations of each technique."
06/01/2006 - "In most patients, ultrasound-guided foam sclerotherapy is a safe treatment for recurrent varicose veins, with an excellent immediate result. "
09/01/1998 - "In addition angiographic sclerotherapy (balloon occluded retrograde transvenous obliteration) is highly effective for large gastric fundal varices and no rebleeding is expected when successfully done. "
09/01/1992 - "For patients with these recurrent varices, endoscopic injection sclerotherapy was very effective and improved the prognosis. "
03/01/1990 - "Long-term injection sclerotherapy is widely accepted as the first line treatment to prevent recurrence of variceal haemorrhage although early rebleeding, prior to the obliteration of varices, represents an important limitation of therapy. "
03/01/2015 - "Foam sclerotherapy or phlebectomy shows good results in patients with vulvar or pudendal varicose veins. "
07/01/2013 - "The aim of this study was to evaluate whether great saphenous vein (GSV) surgery without high ligation of the saphenofemoral junction (SFJ) is beneficial in terms of varicose vein recurrence. "
02/01/2012 - "Until recent years, the gold standard for treatment of truncal varicose veins has been high ligation and stripping of the saphenous vein. "
12/01/1995 - "Following the proposed selection criteria, these two alternative procedures seem to be more effective in varices treatment than high ligation and have the advantage of preserving saphenous veins suitable for eventual by-pass surgery."
11/01/1997 - "Future studies will tell, whether this drug combination is superior to the nowadays established endoscopic eradication of varices, especially by long-term variceal band ligation. "
01/01/1998 - "We concluded that both treatments are equally effective in the eradication of oesophageal varices, although banding ligation is better tolerated by the patient and probably faster."
|3.||Laser Therapy (Surgery, Laser)
07/01/2013 - "Endovenous laser ablation (EVLA) has been demonstrated to be an effective treatment for lower limb varicose veins in the short and midterm results. "
09/01/2007 - "Endovenous laser therapy (EVLT) for the treatment of varicose veins has been shown to be effective and relatively safe. "
02/01/2005 - "Endovenous laser therapy (EVLT) is a new, minimally invasive therapeutic option for treating primary varicose veins and provides an effective and safe alternative to conventional surgical management (stripping). "
02/01/2013 - "Endovascular laser ablation seems to be a safe and effective method for the treatment of lower limb varices."
04/28/2007 - "Endovenous laser therapy appears to be a safe and effective treatment option for refluxing varicose veins."
|4.||Surgical Portasystemic Shunt (Portosystemic Shunt)
09/01/2014 - "The purpose of this study was to determine the safety and efficacy of transjugular intrahepatic portosystemic shunt (TIPS) creation for the treatment of hemorrhagic stomal varices. "
09/01/2014 - "Reduction in portal venous pressure by transjugular intrahepatic portosystemic shunt for treatment of hemorrhagic stomal varices."
11/01/2013 - "Fundal varices had a high prevalence of spontaneous portosystemic shunts compared with other varices. "
11/01/2013 - "Additionally, there was no significant difference in the HVPG between varices with spontaneous portosystemic shunts (n=28) and varices without these shunts (n=57) (18.3±5.8 mm Hg vs 17.0±8.1 mm Hg). "
11/01/2013 - "The interrelationship between HVPG and the types of varices or the presence of spontaneous portosystemic shunts was studied. "
12/01/2006 - "Endovenous lasers with various wavelengths have been utilized with good outcomes in treating leg varicose veins. "
05/01/2012 - "Endovenous ablation, using radiofrequency or laser, is becoming the mainstay of treatment for symptomatic varicose veins in the setting of saphenous vein incompetency. "
11/01/2005 - "We think that laser treatment is effective in the treatment of the primary varicose veins of the legs. "
01/01/2002 - "Recently, endovenous laser occlusion has been introduced with initial clinical reports indicating effective treatment for varicose veins. "
05/01/2004 - "The combination of endovascular laser and ambulatory phlebectomy appear to be an effective and safe treatment approach for the management of combined saphenous and truncal varicose vein incompetence."