Uterine Neoplasms (Uterine Cancer)

668  relevant articles (18 outcomes, 42 trials/studies) found for this Disease

Uterine Cancer; Cancer of the Uterus; Neoplasms, Uterine; Neoplasms, Uterus; Uterus Cancer; Uterus Neoplasms; Cancer, Uterine; Cancer, Uterus; Cancers, Uterine; Cancers, Uterus; Neoplasm, Uterine; Neoplasm, Uterus; Uterine Cancers; Uterine Neoplasm; Uterus Cancers; Uterus Neoplasm; Cancer of Uterus

Relationship Network

Disease Context: Research Results

Related Diseases

1.	Neoplasms (Cancer)
2.	Lung Neoplasms (Lung Cancer)
3.	Breast Neoplasms (Breast Cancer)
4.	Carcinoma (Carcinomatosis)
5.	Rectal Neoplasms (Rectal Cancer)

Experts

1.	Asselin, Eric: 4 articles (02/2008 - 09/2004)
2.	Chan, John K: 3 articles (12/2007 - 06/2007)
3.	Kapp, Daniel S: 3 articles (12/2007 - 06/2007)
4.	Sexton, Emilie: 3 articles (02/2007 - 09/2004)
5.	Van Themsche, Céline: 2 articles (02/2008 - 01/2006)
6.	Gagnon, Véronique: 2 articles (02/2008 - 09/2004)
7.	Shin, Jacob Y: 2 articles (12/2007 - 06/2007)
8.	Cheung, Michael K: 2 articles (12/2007 - 06/2007)
9.	Osann, Kathryn: 2 articles (12/2007 - 06/2007)
10.	Leblanc, Kim: 2 articles (02/2007 - 09/2004)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Uterine Neoplasms:

1.	Estrogens (Estrogen)FDA Link 12/30/2004 - "Numerous studies have suggested that the lifetime dose of unopposed estrogen is a significant risk factor for breast and uterine cancer" 01/10/1979 - "Results of a study conducted by researchers at the University of Pennsylvania and Johns Hopkins were published in the January 4, 1979, issue of "New England Journal of Medicine." The study, which examined 1339 women in menopause, concluded that women who use estrogen drugs have a 6 times greater risk of developing uterine cancer than nonusers" 01/10/1979 - "New study linking estrogen use and uterine cancer was hailed." 02/01/2007 - "Novel estrogenic therapies are needed that ameliorate menopausal symptoms and have the bone-sparing effects of endogenous estrogens but do not promote breast or uterine cancer" 06/08/2005 - "Administering estrogens has serious drawbacks, however--they are feminizing (and thus cannot be administered to males) and may increase the incidence of serious diseases such as uterine cancer in postmenopausal women" Order ALL the reference details at left...
2.	TamoxifenFDA LinkGeneric 05/01/2006 - "The objective of this study was to determine the percentage of women who developed uterine cancer more than 12 months after discontinuing tamoxifen (past users) and to compare their clinical and pathologic features with those of women who developed uterine cancer while on tamoxifen therapy or within 12 months of stopping therapy (recent users)" 10/01/1999 - "Large clinical trials have pointed out that long-term tamoxifen therapy increases the risk of uterine cancers" 03/01/2008 - "Five of the 875 tamoxifen users (0.6%) died of uterine cancer, compared to no deaths among nonusers (P = 0.08)" 03/01/2008 - "There were 17 uterine cancers observed among the 875 exposed to tamoxifen (1.9%), compared to 4 uterine cancers among the 621 women (0.6%) who did not use tamoxifen (odds ratio = 3.1; 95% CI: 1.0-9.1; P = 0.04)" 08/01/2007 - "Tamoxifen benefits all stages of the disease, but its use increases the risk of uterine cancer and thromboembolic events and it can only be administered for 5 years" Order ALL the reference details at left...
3.	Doxorubicin (Adriamycin)FDA LinkGeneric 09/01/1991 - "In summary, Adriamycin remained the most effective single drug for uterine cancer cell lines" 02/01/2005 - "In Vitro study showed that Dox-PNP exhibited higher cellular uptake into both human breast cancer cell (MCF-7) and human uterine cancer cell (MES-SA) than free doxorubicin solution (Free-Dox), especially into drug-resistant cells (MCF-7/ADR and MES-SA/Dx-5)" 05/01/2006 - "OBJECTIVE: The purpose of this study was to investigate whether resveratrol adds to the growth inhibitory effects of cisplatin and doxorubicin on ovarian and uterine cancer cells and to evaluate whether resveratrol diminishes the cardiac toxicity of doxorubicin in rodent heart" 02/01/2008 - "Akt and XIAP regulate the sensitivity of human uterine cancer cells to cisplatin, doxorubicin and taxol." 01/01/1993 - "In summary, Adriamycin, 5-fluorouracil, cisplatin, and mitomycin-C have the potential to be radiosensitizers in uterine cancer cell lines." Order ALL the reference details at left...
4.	Oral ContraceptivesIBA 12/01/1975 - "It is emphasized that, in order to obtain a safe and effective treatment, the prescription of oral contraceptives must follow certain stringent rules: a careful initial examination of the patient is necessary to detect previous cardiovascular, diabetic, or hyperlipemic conditions; clinical and gynecological examinations to detect signs of cancer of the uterus and breasts should also be made before making a decision; careful laboratory studies, especially concerning fat and carbohydrate metabolism, should be performed during treatment; the contraceptive drug should be selected among those containing the lowest doses" 11/01/2003 - "Women that were married, mothers, on menopause, with a family history of cancer, uterine fibroma, past users of oral contraceptives were more likely to having performed Ma, but not US" 04/07/1972 - "Oral contraceptives are contraindicated in cases presenting a history of thromboembolism, phlebitis, cerebral apoplexy; sickle cell anemia, which indicates a predisposition to thromboembolic accidents; serious liver disease or recent hepatitis; serious heart disease; hormone-dependent neoplasia (breast cancer); predisposition to uterine cancer; erythematous lupus; metorrhagia of unknown origin; psychic disorders, especially of a depressive type" 04/15/1977 - "To the evidence for the production by estrogen of malignant uterine neoplasms in rodents and the clinical data showing that cystic glandular hyperplasia develops after prolonged estrogen administration in postmenopausal women and adenocarcinoma in premenopausal or menopausal women using oral contraceptives including ethinyl estradiol, we add the present results which suggest that ethinyl estradiol administered transplacentally can cause malignant transformation of the uterine endometrium in mice." Order ALL the reference details at left...
5.	ProgesteroneFDA LinkGeneric 06/01/2007 - "Progesterone based cervical-uterine-cancer therapy essay" 09/01/1991 - "A combination of oestrogen and progesterone may avoid the increased risk of uterine cancer but what are the effects of long term administration" 11/01/1955 - "Hormonal imbalance in uterine cancer patients; urinary excretion of pregnandiol following progesterone overload before and after surgery and radiotherapy.]" 07/01/1976 - "While the relative nontoxic progesterone compounds are effective in a small but significant fraction of patients with advanced uterine cancer, no properly designed clinical trial has truly evaluated their role as postoperative adjuncts in patients who have resectable tumor but a definite high risk of recurrence" 06/01/2001 - "The nuclear receptor for the female hormone progesterone (PR) is widely expressed in uterine cancer" Order ALL the reference details at left...
6.	Estrogen Receptor Modulators (Antiestrogen)IBA 07/10/1982 - "A new antiestrogen effective against uterine neoplasms]" 02/01/2007 - "The impact of 17beta-estradiol and antiestrogens on uterine cancer cells is poorly understood" 03/01/1994 - "Antiestrogen therapy of patients with uterine cancer]" 02/01/2007 - "Results demonstrated the importance of removing phenol red and the use of deprived serum when studying uterine cancer cells in relationship with 17beta-estradiol and antiestrogens" 12/01/2006 - "We present the successful use of the antiestrogen fulvestrant in an endocrine therapy-naive patient with advanced uterine cancer" Order ALL the reference details at left...
7.	Medroxyprogesterone 17-Acetate (Depo-Provera)FDA LinkGeneric 01/01/1979 - "Depo-Provera may be linked to uterine cancer, preliminary data imply." 08/01/1991 - "The effects of Provera on chemotherapy of uterine cancer cell lines." 04/01/1983 - "Results of the use of chlormadinone and farlutal depot in hormonal therapy of uterine cancer]" 07/15/1994 - "Beneficial effects of Depo-Provera are improvement of hemoglobin levels, protection against uterine cancer, and relief of premenstrual syndrome and dysmenorrhea" 03/01/1978 - "Medroxyprogesterone (Depo-Provera), a progesterone used as an injection for 1) treating cancer of the uterus, and 2) an injectable contraceptive, is approved by 69 countries, manufactured in at least 6 countries, and is distributed to 42 countries by the International Planned Parenthood Federation" Order ALL the reference details at left...
8.	Fluorouracil (Carac)FDA LinkGeneric 10/01/1968 - "Perioperative antiblastic drug therapy with triethyleniminobenzoquinone and 5-fluorouracil in uterine neoplasms]" 04/01/1989 - "She underwent gastrectomy for early gastric cancer (IIc) 5 years earlier, mastectomy for early breast cancer (stage I) 3 years earlier and radiation therapy (60Co 350rad x 25 days) and chemotherapy (5FU, 200 mg/day, orally) for uterine cancer (stage IIb) 2.5 years earlier" 01/01/1980 - "In 62 operated patients with stomach, breast, and uterine cancers, the concentration of 5FU and FT were compared in serum, tumor and normal tissues 1, 2, 4, 6, 8, and 12 hours following the administration of 300 mg of UFT (300 mg of FT plus 672 mg uracil, a uracil/FT molar ratio of 4), or FT alone" 01/01/1993 - "In summary, Adriamycin, 5-fluorouracil, cisplatin, and mitomycin-C have the potential to be radiosensitizers in uterine cancer cell lines." 05/01/1992 - "When using an IC50 of 0.21 PPC (peak plasma concentration) as a cutoff value for sensitivity, the following 8 drugs were considered effective for uterine cancer cell lines: actinomycin D, Adriamycin, vinblastine, etoposide, 5-fluorouracil, methotrexate, cytosine arabinoside, and mitomycin-C" Order ALL the reference details at left...
9.	Etoposide (VP 16)FDA LinkGeneric 08/01/1999 - "The antitumor activity of etoposide (ETP) against human uterine cancer cell lines were investigated in vitro and in vivo" 08/01/1999 - "Evaluation of antitumor activity of etoposide administered orally for 21 consecutive days against human uterine cancer subcutaneous and/or orthotopic xenografts in nude mice]" 01/15/1989 - "ACRO in this etoposide diluent (VPD) was found to be cytotoxic (less than or equal to 50% colony formation in soft agar) in fresh human tumors from patients with renal cell cancer, ovarian cancer, uterine cancer, and metastatic tumors of unknown primary" 07/01/2004 - "BG-1 ovarian cancer cells and HeLa uterine cancer cells were treated with a tubulin depolymerization inhibitor (paclitaxel), a topoisomerase-II inhibitor (etoposide), and two tubulin polymerization inhibitors (colcemid and vincristine)" 05/01/1992 - "When using an IC50 of 0.21 PPC (peak plasma concentration) as a cutoff value for sensitivity, the following 8 drugs were considered effective for uterine cancer cell lines: actinomycin D, Adriamycin, vinblastine, etoposide, 5-fluorouracil, methotrexate, cytosine arabinoside, and mitomycin-C" Order ALL the reference details at left...
10.	CarbonIBA 01/01/2006 - "The effects of carbon ion irradiation revealed by excised perforated intestines as a late morbidity for uterine cancer treatment." 07/01/2006 - "MATERIALS AND METHODS: Chromosome-type aberrations of peripheral lymphocytes of uterine cancer patients that received internal gamma- and external X-ray therapy or carbon beam therapy and of victims severely exposed to neutrons and gamma-rays in a criticality accident that occurred in Tokai-mura, Japan were analysed" 01/01/2006 - "Perforated intestines as a late morbidity after carbon ion radiotherapy for uterine cancers were examined to reveal the biological characteristics of carbon ion for future applications for the treatment of gastrointestinal cancers" 10/01/2004 - "On the other hand, carbon-ion beam therapy is giving good results in some selected carcinoma such as small cell lung cancer, prostate cancer, uterus cancer, and soft tissue/bone tumor" 01/01/2004 - "In particular, we studied data from astronauts involved in long-term missions in low-Earth-orbit, and uterus cancer patients treated with accelerated carbon ions" Order ALL the reference details at left...

Therapies and Procedures

1.	Drug Therapy (Chemotherapy) 02/01/2008 - "Chemotherapy of uterine cancer]" 01/01/2005 - "Thirty-three women on a chemotherapy ward in the northwest of England who had breast, ovarian, cervical or uterine cancer were interviewed using a Concerns Checklist and the Hospital Anxiety and Depression Scale" 08/01/1993 - "Three cases of advanced uterine cancer were treated by CDDP intra-arterial infusion chemotherapy before curative operation" 08/01/1993 - "Intra-arterial infusion chemotherapy for advanced uterine cancer before surgical treatment]" 11/01/1992 - "CONCLUSION: These results suggest that hypertensive intra-arterial chemotherapy induces a selective marked increase of blood flow in uterine cancer." Order ALL the reference details at left...
2.	Lymph Node Excision (Lymph Node Dissection) 08/01/2007 - "CONCLUSIONS: Our data suggest that lymphadenectomy is associated with an improved survival in stage I grade 3 and more advanced endometrioid uterine cancers." 06/01/2008 - "The incorporation of lymphadenectomy into the surgical management of uterine cancer has accompanied a dramatic reduction in the use of peri-operative radiotherapy" 06/01/2008 - "However, 30 years ago, realization of the metastatic potential of this disease, particularly to regional lymph nodes, led many clinicians to include lymphadenectomy in the surgical management of uterine cancer" 09/01/2007 - "Role of complete lymphadenectomy in endometrioid uterine cancer." 08/01/2007 - "RESULTS: Of 39,396 women (median age: 65 years) with endometrioid uterine cancers, 12,333 (31.3%) underwent surgical staging procedures including lymphadenectomy" Order ALL the reference details at left...
3.	Hysterectomy 04/01/1990 - "The gravity of the pelvic lymphocysts after extended lymphadeno-colpo-hysterectomies for uterine cancers has been outlined in many studies and only a preventive strategy can reduce the morbidity, which is mainly of urinary order" 01/01/1967 - "Study of urographic results of lymphadeno-colpo-hysterectomy in the treatment of uterine cancer]" 06/01/2008 - "We conducted a multi-institute survey on the conditions related to urologic management of severe voiding dysfunction after hysterectomy for uterine cancer with or without postoperative irradiation" 09/01/2007 - "She had a history of total hysterectomy followed by radiotherapy due to uterine cancer 30 years previously" 10/01/2006 - "Case 1 was a 47-year-old female with a history of radical hysterectomy for cervical cancer of the uterus" Order ALL the reference details at left...
4.	Ovariectomy (Oophorectomy) 03/15/2003 - "In women of childbearing age, a more conservative unilateral salpingo-oophorectomy may be performed, assuming that careful staging reveals that the disease has not extended outside of the involved ovary and that a concomitant uterine cancer has been excluded" 07/01/2007 - "A total of 190 patients with newly diagnosed uterine cancer who underwent total abdominal hysterectomy (TAH), bilateral salpingo-oophorectomy (BSO), omentectomy, peritoneal w