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Urokinase-Type Plasminogen Activator (Urokinase)

A proteolytic enzyme that converts PLASMINOGEN to FIBRINOLYSIN where the preferential cleavage is between ARGININE and VALINE. It was isolated originally from human URINE, but is found in most tissues of most VERTEBRATES.
Also Known As:
Urokinase; Urokinase Type Plasminogen Activator; U-PA; U-Plasminogen Activator; Abbokinase; Kidney Plasminogen Activator; Renokinase; Single-Chain Urokinase-Type Plasminogen Activator; Single Chain Urokinase Type Plasminogen Activator; U Plasminogen Activator; Plasminogen Activator, Urokinase-Type; Urinary Plasminogen Activator
Networked: 5186 relevant articles (240 outcomes, 576 trials/studies)

Relationship Network

Drug Context: Research Results

Experts

1. Rao, Jasti S: 37 articles (05/2014 - 01/2002)
2. Schmitt, Manfred: 36 articles (04/2015 - 01/2002)
3. Høyer-Hansen, Gunilla: 26 articles (11/2015 - 05/2002)
4. Magdolen, Viktor: 25 articles (04/2015 - 01/2002)
5. Ploug, Michael: 24 articles (12/2015 - 01/2004)
6. Gondi, Christopher S: 23 articles (09/2013 - 05/2003)
7. Eugen-Olsen, Jesper: 22 articles (10/2015 - 01/2004)
8. Yang, Shun-Fa: 22 articles (01/2014 - 07/2004)
9. Schmitt, M: 22 articles (05/2013 - 01/2000)
10. Brünner, Nils: 21 articles (11/2015 - 01/2002)

Related Diseases

1. Thrombosis (Thrombus)
2. Myocardial Infarction
3. Stroke (Strokes)
4. Neoplasms (Cancer)
5. Venous Thrombosis (Deep-Vein Thrombosis)

Related Drugs and Biologics

1. Tissue Plasminogen Activator (Alteplase)
2. Plasminogen Activators (Plasminogen Activator)
3. Streptokinase
4. Heparin (Liquaemin)
5. Plasminogen
6. Anti-Bacterial Agents (Antibiotics)
7. Plasminogen Activator Inhibitor 1
8. Fibrinolytic Agents (Antithrombotic Agents)
9. Batroxobin
10. Fibrin

Related Therapies and Procedures

1. Catheters
2. Thrombolytic Therapy
3. Angioplasty (Angioplasty, Transluminal)
4. Transplants (Transplant)
5. Stents