|2.||Respiratory Tract Infections (Respiratory Tract Infection)
|4.||Soft Tissue Infections
|1.||Saint, Sanjay: 35 articles (07/2015 - 06/2003)|
|2.||Mobley, Harry L T: 35 articles (06/2015 - 01/2002)|
|3.||Hultgren, Scott J: 24 articles (07/2015 - 05/2003)|
|4.||Arakawa, Soichi: 23 articles (09/2015 - 06/2004)|
|5.||Kumon, Hiromi: 20 articles (09/2015 - 08/2002)|
|6.||Monden, Koichi: 20 articles (08/2012 - 08/2002)|
|7.||Rosenthal, Victor D: 19 articles (11/2015 - 04/2006)|
|8.||Trautner, Barbara W: 19 articles (09/2015 - 05/2003)|
|9.||Matsumoto, Tetsuro: 19 articles (09/2015 - 11/2002)|
|10.||Nicolle, Lindsay E: 19 articles (09/2014 - 01/2002)|
|1.||Trimethoprim-Sulfamethoxazole Combination (Co-Trimoxazole)FDA LinkGeneric
08/08/1990 - "In over 6 months of observation, postcoital administration of trimethoprim-sulfamethoxazole was highly effective in preventing recurrent urinary tract infections. "
05/01/2002 - "This study evaluated whether trimethoprim-sulfamethoxazole (TMP-SMX) is effective for treatment of uncomplicated urinary tract infections (UTIs) due to TMP-SMX-resistant (TMP-SMX-R) pathogens. "
06/01/1985 - "Single-dose trimethoprim-sulfamethoxazole is as effective as ten-day treatment in women with symptoms suggestive of lower urinary tract infection and has no greater relapse rate."
01/01/2001 - "The aim of the study was to determine the efficacy of cotrimoxazole administration after urodynamic testing to prevent urinary tract infections. "
06/01/1988 - "Efficacy of five years of continuous, low-dose trimethoprim-sulfamethoxazole prophylaxis for urinary tract infection."
|2.||Ciprofloxacin (Cipro)FDA LinkGeneric
05/01/1987 - "As the concentration of ciprofloxacin in urine after 24 h remained above the MIC for most urinary pathogens, this drug appears to be of potential benefit for the treatment of urinary tract infections in patients with impaired renal function."
03/01/2015 - "We conclude that ciprofloxacin is a safe and effective therapeutic alternative for the treatment of acute or complicated urinary tract infections in adults."
03/01/1996 - "The therapeutic efficacy of intravenous ciprofloxacin against experimentally induced urinary tract infections in mice was compared to that after oral dosing by determining viable bacteria count in kidney 24h after inoculation. "
03/01/1996 - "The therapeutic efficacy of intravenous ciprofloxacin against experimentally induced systemic, respiratory tract and urinary tract infections was investigated in mice. "
11/01/1986 - "Ciprofloxacin appears to be an effective and safe orally-administrable treatment even for complicated urinary tract infection."
|3.||Anti-Bacterial Agents (Antibiotics)IBA
01/01/2006 - "For treatment of complicated hospital-acquired urinary tract infections, the antibiotics must exhibit adequate pharmacodynamic and pharmacokinetic properties: high renal clearance of unmetabolized form with good antimicrobial activity in both acidic and alkaline urine. "
01/01/2003 - "Antibiotics, high fluid intake, and fruit extracts, such as cranberry juice, have all been found to be effective in the treatment of urinary tract infections. "
06/01/1988 - "Effective post-coital prophylaxis requires the use of much smaller quantities of antibacterial agents than the daily use of a single tablet and in women with a high incidence of recurrent urinary tract infections it is superior to intermittent self-administered antibacterial therapy."
06/01/2014 - "Urinary tract infection (UTI) is a major problem in nursing homes, and the mainstay of treatment is antibiotics. "
01/01/1996 - "The aim of this study was to prospectively evaluate the efficacy of a therapeutic course of intravenous antibiotics followed by oral antibiotics vs. intravenous antibiotics alone to prevent recurrent urinary tract infection. "
01/01/1990 - "Norfloxacin was also highly effective in the treatment of multiply resistant, nosocomial urinary tract infections (UTIs), in which Pseudomonas aeruginosa and E. "
04/01/1998 - "Norfloxacin 400 mg twice-a-day has proven to be effective and safe in the treatment of uncomplicated urinary tract infections (UTI). "
06/01/1992 - "-Three days of norfloxacin therapy is more effective than single-dose therapy for women with acute, uncomplicated urinary tract infection. "
01/01/1988 - "The therapeutic efficacy and safety of norfloxacin 400 mg twice daily for 3 or 7 days was compared in a double-blind randomized multiclinic study including 485 female general practice patients with uncomplicated symptomatic lower urinary tract infections. "
04/01/1998 - "In this study, norfloxacin 800 mg once-a-day was as effective and safe as norfloxacin 400 mg twice-a-day in the treatment of uncomplicated urinary tract infections in women."
|5.||Trimethoprim (Proloprim)FDA LinkGeneric
04/11/1980 - "Since diabetics frequently suffer from urinary tract infections which can be successfully treated with a combination of sulphonamide derivatives and the bacteriocide trimethoprim, the question of possible interactions between such agents and diabetic therapy is of interest. "
06/01/1991 - "The efficacy of single dose treatment with trimethoprim compared to a 5-day course with the same drug was investigated in 100 children, 3-12 years, with isolated episodes of symptomatic non-febrile urinary tract infection. "
06/01/2001 - "The objective of this study was to evaluate the association between exposure to community-prescribed trimethoprim and other risk factors in subjects and subsequent trimethoprim-resistant urinary tract infection. "
02/01/1988 - "In the first study to assess the effect of trimethoprim in the treatment of acute urinary tract infections in children, we compared it with sulphisoxazole. "
12/01/2014 - "The use of recommended short-course trimethoprim for urinary tract infection (UTI) in women aged 16-74 years increased from 8% in 1995 to 50% in 2011; however, a quarter of practices prescribed short courses in ≤16% of episodes in 2011. "
|6.||Ofloxacin (Levofloxacin)FDA LinkGeneric
01/01/1996 - "In the treatment of patients with noncomplicated urinary tract infection good results (the clinical and bacteriological efficacies of 96 and 88 per cent respectively) were observed when ofloxacin was used orally in a single dose of not more than 400 mg once a day for 3 to 5 days. "
03/01/2003 - "These study results indicate that levofloxacin 250 mg orally once daily for 10 days is an effective and well tolerated treatment of complicated urinary tract infections."
08/01/1987 - "This study showed that Ofloxacin is effective against urinary tract infections."
01/01/1988 - "The clinical efficacy of the new quinolone antibacterial agent ofloxacin (OFLX) on urinary tract infections (UTI) was reevaluated. "
04/01/1994 - "In comparative trials with ofloxacin, levofloxacin, at half the daily dosage of ofloxacin, showed equivalent efficacy and a reduced incidence of adverse effects in the treatment of lower respiratory tract and complicated urinary tract infections. "
|7.||Amoxicillin (Wymox)FDA LinkGeneric
12/01/1982 - "We conclude that a single 3 g dose of amoxicillin, with follow-up urine culture, provides safe and effective management for acute uncomplicated urinary tract infections in nonpregnant women."
02/23/1978 - "Efficacy of single-dose and conventional amoxicillin therapy in urinary-tract infection localized by the antibody-coated bacteria technic."
02/01/2006 - "The data collected were compared with those of a previous trial performed in the same setting and documenting the effectiveness and advantages associated with the use of amoxicillin against community-acquired uncomplicated urinary tract infections (UTI). "
06/01/1983 - "A comparative trial of amoxycillin 3g bd and conventional amoxycillin therapy in the treatment of urinary tract infection in a general practice population."
02/01/1983 - "[Clinical study on long acting amoxicillin in urinary tract infection]."
|8.||Nitrofurantoin (Macrodantin)FDA LinkGeneric
10/01/2010 - "Nitrofurantoin shows good efficacy against most bacteria expected in urinary tract infection, and the development of resistance is low. "
10/01/2010 - "The results of the present study indicate good antimicrobial and clinical efficacy of nitrofurantoin in the treatment of acute uncomplicated urinary tract infections as well as acceptable tolerability in adults."
10/12/2012 - "Nitrofurantoin has been in use since 1953 as an effective agent for the prevention of recurrent urinary tract infection. "
01/01/1983 - "Nitrofurantoin is equally effective in urinary tract infections. "
12/01/1981 - "Three days of treatment with nitrofurantoin macrocrystals is an effective regimen for symptomatic girls presumed to have uncomplicated lower urinary tract infections."
|9.||Gentamicins (Gentamicin)FDA LinkGeneric
06/01/1997 - "The results indicate that one bolus dose of gentamicin with early oral therapy is a safe and effective alternative to common parenteral regimens for empirical treatment of febrile urinary tract infection."
03/01/2001 - "To undertake population pharmacokinetic modeling and to determine the safety and efficacy of once daily (OD) gentamicin dosing in children with severe urinary tract infections (UTI). "
01/01/1992 - "Efficacy of prophylactic gentamicin use in postoperative urinary tract infections after endoscopic procedures of the urinary tract."
01/01/1987 - "We evaluated the efficacy of a single dose of gentamicin in patients with normal urinary tracts and in whom urinary tract infections were recurrent. "
12/01/1973 - "[A double-blind comparison of the efficacy of DKB and gentamicin in urinary tract infections (author's transl)]."
10/01/2003 - "There were few important side effects with fosfomycin therapy and it was considered a safe and effective first line treatment in uncomplicated urinary tract infection."
01/01/2012 - "Oral treatment with fosfomycin tromethamine is effective against lower urinary tract infections (UTIs) caused by ESBL-producing Escherichia coli. "
05/01/1981 - "The efficacy of fosfomycin in urinary tract infections was investigated with a dose of 15 g/day. "
01/01/1969 - "Efficacy of phosphonomycin in treatment of urinary-tract infections."
05/01/2015 - "The aim this study was to determine the in vitro susceptibility to fosfomycin of bacteria isolated from urine samples of pregnant women with urinary tract infection. "
03/01/2013 - "Their knowledge improved significantly, mainly in terms of: a) antimicrobial activity of alcohol-based solutions, b) preventive measures for cathether-associated urinary tract infections, and c) best place to insert a central venous catheter. "
05/01/1995 - "It also resulted in a highly statistically significant reduction of symptomatic urinary tract infections (1 vs. 12, p < 0.02), a decrease in catheter-associated local complications, obstructions and leakage (p < 0.05) and an improvement in the patients' general condition (p < 0.001). "
05/01/2004 - "Currently, no proven effective strategies exist for prevention of catheter-associated urinary tract infection in persons who are chronically catheterized."
01/01/2006 - "CLAMP AND RELEASE POLICIES BEFORE CATHETER REMOVAL VERSUS IMMEDIATE CATHETER REMOVAL: In a single small trial, the clamp-and-release group showed a significantly greater incidence of urinary tract infections (RR 4.00, 95% 1.55 to 10.29) and a delay in return to normal voiding (RR 2.50, 95% CI 1.16 to 5.39). "
09/01/2014 - "A series of evidence-based interventions were implemented in October 2011, and since the implementation of these interventions, the 28-bed unit has seen a significant reduction in catheter-associated urinary tract infections."
04/01/2013 - "Antibiotic prophylaxis appears to be an effective intervention in preventing urinary tract infections and its sequels following transurethral urological surgeries in patients with preoperative sterile urine. "
12/01/2013 - "Aim of this study is to evaluate the efficacy of a phytotherapic which includes Solidago, Orthosiphon and Birch extract (Cistimev®) in association with antibiotic prophylaxis in female patients affected by recurrent urinary tract infections (UTIr). "
08/08/1990 - "We conducted a randomized, double-blind, placebo-controlled study to determine the efficacy of postcoital antibiotic prophylaxis in healthy young women prone to recurrent urinary tract infections. "
05/01/2015 - "To estimate the efficacy of antibiotic prophylaxis to prevent urinary tract infection in patients (both gender) who undergo a cystoscopy with sterile urine. "
05/01/2015 - "Efficacy of antibiotic prophylaxis in cystoscopy to prevent urinary tract infection: a systematic review and meta-analysis."
10/01/2009 - "after treatment 14.6%, P < 0.01); a complete MDR gram-negative bacillus clearance of urine was observed in 1 patient with urinary tract infection. "
01/01/1984 - "Twenty seven out of 34 organisms isolated from chronic complicated urinary tract infections before administration of CTX were eradicated after treatment. "
01/01/2015 - "Mean urethral closure pressure and maximum urethral closure pressure decreased significantly with a more significant decrease for patients in group 3. The prevalence of urinary tract infection decreased significantly in all groups after treatment, and this decrease remained stable during the follow up. "
01/01/2015 - "A routine follow-up urine sample (FUS) in the form of a midstream urine sample (MSU) is recommended after treatment for urinary tract infection (UTI) according to the Danish Paediatric Society (DPS) and "Lægehåndbogen" published by Danish Regions. "
01/01/2015 - "A follow-up urine sample has limited value after treatment for urinary tract infection in children."
05/01/2015 - "Study of the risk factors related to acquisition of urinary tract infections in patients submitted to renal transplant."
11/01/2013 - "We describe the treatment and outcomes of 6 renal transplant patients who had urinary tract infections (UTIs) with blaKPC-2-producing K pneumoniae, confirmed by polymerase chain reaction amplification, namely 13.33% of renal transplant patients in the study period. "
10/01/2010 - "Twenty three recipients of the study developed early graft dysfunction due to urinary tract infection. "
10/01/2010 - "Our study group describes seven patients with functioning kidney grafts and a diagnosis of VUR associated with recurrent urinary tract infections. "
10/01/2010 - "In this study there was no correlation between a history of urinary tract infection (either before or after transplant) and decreased graft function. "
|5.||Drug Therapy (Chemotherapy)
02/01/2011 - "This study was conducted by the Japanese Society of Chemotherapy and is the first nationwide study on bacterial pathogens isolated from patients with urinary tract infections at 28 hospitals throughout Japan between January 2008 and June 2008. "
02/01/2011 - "The nationwide study of bacterial pathogens associated with urinary tract infections conducted by the Japanese Society of Chemotherapy."
03/01/1994 - "[Study on MIC breakpoint and method of antimicrobial chemotherapy for moderately complicated urinary tract infection--study using an automatic simulator of urinary antimicrobial agent concentrations]."
10/01/1983 - "Application of non-animal models to studies of the chemotherapy of bacterial urinary tract infections."
02/01/1970 - "[Studies on chemotherapy of urinary tract infection]."