Ureteral Calculi

Stones in the URETER that are formed in the KIDNEY. They are rarely more than 5 mm in diameter for larger renal stones cannot enter ureters. They are often lodged at the ureteral narrowing and can cause excruciating renal colic.

Also Known As:

Networked: 867 relevant articles (108 outcomes, 80 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1.	Shock
2.	Calculi (Calculus)
3.	Hydronephrosis
4.	Renal Colic
5.	Kidney Calculi (Kidney Stone)

Experts

1.	Sarica, Kemal: 6 articles (08/2021 - 06/2010)
2.	Xia, Shu-Jie: 5 articles (12/2017 - 10/2008)
3.	Nakada, Stephen Y: 5 articles (03/2016 - 04/2008)
4.	Eryildirim, Bilal: 4 articles (08/2021 - 02/2015)
5.	Wei, Qiang: 4 articles (05/2019 - 02/2009)
6.	Sun, Xiao-Wen: 4 articles (12/2017 - 10/2008)
7.	Assimos, Dean G: 4 articles (01/2017 - 01/2003)
8.	Wolf, J Stuart: 4 articles (04/2015 - 08/2007)
9.	Preminger, Glenn M: 4 articles (04/2013 - 07/2002)
10.	Ding, Qiang: 4 articles (09/2012 - 02/2007)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Ureteral Calculi:

1.	Tamsulosin (Flomax)FDA LinkGeneric 05/01/2010 - "The efficacy of tamsulosin in lower ureteral calculi." 01/01/2018 - "The aim of this study was to evaluate a new technology, extracorporeal physical vibrational lithecbole (EPVL) combined with tamsulosin, as a treatment for distal ureteral calculi (DUC). " 06/01/2010 - "Tamsulosin to treat uncomplicated distal ureteral calculi: a double blind randomized placebo-controlled trial." 02/01/2022 - "Key Words: Tamsulosin, Ureteral calculi, Ureteroscopy." 01/01/2022 - "In several cases, tamsulosin was used off-label, for the treatment of ureteral calculi expulsion. "
2.	silodosinFDA Link 01/01/2015 - "The results of these studies, which all evaluated the efficacy of 8 mg/day, indicate that silodosin is a potential treatment for ureteral calculi. " 04/01/2018 - "We conducted a systematic review and meta-analysis to determine the efficacy and safety of silodosin in MET for ureteral calculi. " 06/01/2013 - "A total of 112 male patients, who were referred to our department for the management of symptomatic unilateral distal ureteral calculi of less than 10 mm, were randomly divided into two groups: group A (56 patients) who were instructed to drink 2 L of water daily and group B (56 patients) who received the same instruction and were also given silodosin (8 mg/daily) for a maximum of 4 weeks. " 09/01/2011 - "A total of 187 male patients, who were referred to our department for the management of symptomatic unilateral ureteral calculi of less than 10 mm, were randomly divided into two groups: group A (92 patients), who were instructed to drink 2 L of water daily, and group B (95 patients), who received the same instruction and were also given silodosin (8 mg/daily) for a maximum of 8 weeks. " 04/01/2018 - "Role of silodosin as medical expulsive therapy in ureteral calculi: a meta-analysis of randomized controlled trials."
3.	PhloroglucinolIBA 03/28/2023 - "Conclusions combination use of ketochromate tromethamine and phloroglucinol significantly improve early expulsion of ureteral calculi after ESWL in patients with distal ureteral calculi, with no side effect. " 03/01/2018 - "Efficacy of Tamsulosin alone versus Tamsulosin Phloroglucinol combination therapy for medical expulsion of lower Ureteral calculi." 03/28/2023 - "Objective: To evaluate the efficacy of ketochromate tromethamine and phloroglucinol combination therapy in early expulsion of ureteral calculi after extracorporeal shockwave lithotripsy (ESWL) in patients with distal ureteral clculi. " 07/01/2005 - "A total of 210 symptomatic patients with distal ureteral calculi greater than 4 mm were randomly allocated to home treatment with phloroglucinol, tamsulosin or nifedipine (groups 1 to 3, respectively). " 07/01/2005 - "Randomized trial of the efficacy of tamsulosin, nifedipine and phloroglucinol in medical expulsive therapy for distal ureteral calculi."
4.	Nifedipine (Adalat)FDA LinkGeneric 01/01/2016 - "Comparative efficacy of tamsulosin versus nifedipine for distal ureteral calculi: a meta-analysis." 01/01/2016 - "On the bias of current evidence, tamsulosin showed an overall superiority to nifedipine for distal ureteral calculi <10 mm in aspects of expulsion rate, expulsion time, and safety. " 07/01/2006 - "MeSH headings included ureteral calculi, nifedipine, doxazosin, and adrenergic alpha-antagonists. " 07/01/2005 - "A total of 210 symptomatic patients with distal ureteral calculi greater than 4 mm were randomly allocated to home treatment with phloroglucinol, tamsulosin or nifedipine (groups 1 to 3, respectively). " 07/01/2005 - "Randomized trial of the efficacy of tamsulosin, nifedipine and phloroglucinol in medical expulsive therapy for distal ureteral calculi."
5.	alfuzosin (UroXatral)FDA Link 06/01/2008 - "Alfuzosin stone expulsion therapy for distal ureteral calculi: a double-blind, placebo controlled study." 02/01/2013 - "We evaluated the efficacy of alfuzosin for the treatment of ureteral calculi less than 10 mm in diameter after extracorporeal shock wave lithotripsy (ESWL). " 02/01/2013 - "Efficacy of alfuzosin after shock wave lithotripsy for the treatment of ureteral calculi." 05/01/2012 - "Comparison and efficacy of low-dose and standard-dose tamsulosin and alfuzosin in medical expulsive therapy for lower ureteral calculi: prospective, randomized, comparative study." 03/01/2011 - "Medical treatment of distal ureteral calculi with alfuzosin, doxazosin and terazosin resulted in a significantly increased stone-expulsion rate and decreased expulsion time when compared with HBB. "
6.	Analgesics (Analgesic Drugs)IBA 01/01/2020 - "In selected cases, early ureteroscopy is an effective and safe method for distal ureteral calculi smaller than 10 mm that are painful and resistant to analgesic treatment." 12/01/2016 - "There were no significant differences between the two groups in the radiation exposure dose (5.29 and 5.08 mSv, respectively; P=0.392), amount of analgesics (P=0.341), proportion of patients with diseases other than ureteral calculus (13.0% and 6.8%, respectively; P=0.486), and proportion of patients with unexpected ED revisits within 7 days from the index visit (7.8% and 9.6%, respectively; P=1.000). " 12/01/2016 - "The secondary outcomes were radiation exposure, amount of analgesics, proportion of patients with diseases other than ureteral calculus, and proportion of patients with unexpected ED revisits within 7 days from the index visit. " 01/01/1999 - "In the majority of patients undergoing uncomplicated ureteroscopy for removal of distal ureteral calculi postoperative discomfort is modest, lasts less than 2 days and is easily controlled with oral analgesics. " 01/01/1999 - "A total of 93 patients undergoing uncomplicated, complete removal of distal ureteral calculi were contacted 1 to 3 days and 7 to 10 days postoperatively to determine analgesic requirements and time of return to normal activity. "
7.	HolmiumIBA 10/01/1997 - "This study compared electrohydraulic and holmium:YAG lithotripsy for ureteral calculi. " 10/01/1997 - "For ureteral calculi less than 15 mm. electrohydraulic lithotripsy was more rapid than the holmium:YAG procedure but for ureteral calculi 15 mm. or greater the holmium:YAG technique was more rapid than electrohydraulic lithotripsy. " 10/01/1997 - "Two cohorts of consecutive patients with ureteral calculi treated with ureteroscopic electrohydraulic or holmium:YAG lithotripsy were retrospectively compared. " 10/01/1997 - "Ureteroscopic management of ureteral calculi: electrohydraulic versus holmium:YAG lithotripsy." 01/01/1995 - "The holmium (Ho:YAG) laser can effectively fragment ureteral calculi of all compositions. "
8.	Radio-Opaque acrylic resinIBA 01/01/2020 - "Patients and Methods: Patients with a solitary radio-opaque upper ureteral calculus diagnosed on noncontrast computed tomography were included. " 01/01/2018 - "Between May 2013 and August 2015, patients with radio-opaque distal ureteral calculi of ≤ 1 cm in size were randomized to undergo fluoroless-URS or standard URS. " 06/01/2004 - "Placement of percutaneous nephrostomy in patients with radio-opaque ureteral calculi in solitary kidney could give us a chance to make the lithotripsy easier. " 06/01/2010 - "The objective of this study is to assess the efficacy of an alpha-1 adrenergic receptor blocking agent on the spontaneous passage of proximal ureteral calculi < or =10 mm. 92 patients having single radio-opaque proximal ureteral stone < or =10 mm were randomized into two groups. "
9.	alpha-1 Adrenergic Receptors (alpha 1 Adrenergic Receptor)IBA 08/01/2020 - "In this retrospective single-center cohort study, we investigated the impact of preoperative use of an alpha-1 adrenergic receptor (AR) blocker on the outcome of single-session extracorporeal shock wave lithotripsy (SWL) in 193 male patients who underwent SWL for a single ureteral calculus between 2006 and 2016. " 06/01/2010 - "The objective of this study is to assess the efficacy of an alpha-1 adrenergic receptor blocking agent on the spontaneous passage of proximal ureteral calculi < or =10 mm. 92 patients having single radio-opaque proximal ureteral stone < or =10 mm were randomized into two groups. "
10.	Adrenergic Receptors (Adrenergic Receptor)IBA 12/01/2005 - "It has recently been demonstrated that specific adrenoceptors subtypes (alpha(1A)/alpha(1D)) are prevalent in the distal part of the ureter, a finding supporting the interesting results obtained by different groups with the use of tamsulosin in the treatment of distal ureteral calculi. " 01/01/2015 - "Few studies have investigated the efficacy of silodosin, a recently introduced selective alpha 1-A adrenoceptor antagonist, in medical expulsive therapy (MET) for ureteral calculi. "

Therapies and Procedures

1.	Lithotripsy (Extracorporeal Shockwave Lithotripsy) 09/01/2014 - "Shockwave lithotripsy (SWL) is the gold standard treatment of patients with most renal and proximal ureteral calculi. " 12/01/1998 - "Although extracorporeal shockwave lithotripsy (SWL) is a successful treatment for ureteral calculi, introduction of miniureteroscopes has advanced endoscopic management. " 01/25/2022 - "Supine is Superior to Prone Position in Treating the Distal Ureteral Calculi During Extracorporeal Shockwave Lithotripsy: An Updated Meta-Analysis." 12/01/2005 - "Ureteroscopic pneumatic lithotripsy is a safe and effective treatment modality for ureteral calculi." 09/01/2004 - "Pneumatic lithotripsy has been shown to be an effective and safe intracorporeal lithotripsy modality for renal and ureteral calculi, capable of fragmenting stones of all compositions. "
2.	Therapeutics 11/01/2004 - "This study demonstrated that URSL achieved excellent results for upper ureteral calculi greater than 1 cm. Thus, this procedure should be considered first line therapy for large proximal ureteral stones." 10/01/1988 - "A comprehensive metabolic evaluation combined with selective medical therapy provides almost complete relief from recurrent stone formation and makes medical therapy an integral component of treating the patient with renal or ureteral calculi." 02/01/2014 - "Medical expulsive therapy (MET) using alpha-blockers is effective for distal ureteral calculi (UC). " 07/01/2005 - "We performed a randomized, prospective study to assess and compare the efficacy of 3 drugs as medical expulsive therapy for distal ureteral calculi. " 02/01/2010 - "Of 166 health maintenance organization patients with ureteral calculi who met all study requirements 97 (58.4%) were prescribed medical expulsive therapy and 53 (31.9%) filled the medical expulsive therapy prescription, while 113 did not. "
3.	Solid-State Lasers 09/04/2020 - "Analysis of the efficacy of holmium laser and pneumatic ballistic in the treatment of impacted ureteral calculi." 11/01/2016 - "Safety and Efficacy of Pneumatic Lithotripters Versus Holmium Laser on Multiple Ureteral Calculi." 01/01/2013 - "Safety and efficacy of pneumatic lithotripters versus holmium laser in management of ureteral calculi: a randomized clinical trial." 01/01/1998 - "Safety and efficacy of the Alexandrite laser for the treatment of renal and ureteral calculi." 01/14/2020 - "A 41 years old female underwent left endoscopic ureterolithotomy with holmium laser for ureteral calculi. "
4.	Stents 03/01/2023 - "Flexible ureteroscopy using double-J stent free mode was found to be safe, feasible and effective in treating renal and upper ureteral calculi." 08/28/2014 - "Like calculi, ureteral stents are assigned color by the dual-energy post-processing algorithm, which may lead to improved or worsened stone visualization based on the resulting stent/stone contrast. " 01/01/2020 - "In this single academic center study (Fast Track Stent study 2), carried out between May 2016 and April 2018, 121 patients with renal or ureteral calculi were initially treated with double-J insertion. " 03/01/2023 - "To evaluate the effectiveness and safety of flexible ureteroscopy in the treatment of kidney and upper ureteral calculi under double-J stent free mode. " 05/01/2022 - "YMT is helpful to reduce the formation of bacterial biofilms on ureteral stents and the incidence of symptomatic UTIs related to ureteral stenting after surgery for ureteral calculi. "
5.	Percutaneous Nephrolithotomy 01/01/2005 - "To assess the safety and efficacy of antegrade percutaneous nephrolithotomy (PCNL) of large impacted proximal-ureteral calculi. " 03/01/2023 - "We report the case of an 88-year-old female with complex high-volume renal and ureteral calculus who was treated successfully using a tubeless mini-percutaneous nephrolithotomy. " 03/01/2023 - "Tubeless mini-percutaneous nephrolithotomy to remove a staghorn stone concurrent with proximal ureteral calculus in an elderly patient: A case report." 11/01/2019 - "To summarize the experience of retroperitoneal laparoscopic ureterolithotomy (RLU) in the treatment of upper ureteral calculi and long-term follow-up results and compare them with ureteroscopic lithotomy (URL) and percutaneous nephrolithotomy (PCNL). " 10/21/2019 - "Management of Large Proximal Ureteral Calculi: A Three-year Multicenter Experience of Simultaneous Supine Percutaneous Nephrolithotomy and Retrograde Ureterolithotripsy."