|1.||Kurup, Ravi Kumar: 16 articles (12/2003 - 06/2002)|
|2.||Kurup, Parameswara Achutha: 16 articles (11/2003 - 06/2002)|
|3.||Hargreaves, Iain P: 7 articles (10/2015 - 04/2007)|
|4.||Littarru, Gian Paolo: 7 articles (02/2013 - 01/2005)|
|5.||Kurup, P A: 7 articles (12/2001 - 05/2000)|
|6.||Navas, Plácido: 6 articles (07/2014 - 01/2005)|
|7.||Hirano, Michio: 6 articles (08/2012 - 03/2008)|
|8.||Tiano, Luca: 6 articles (11/2011 - 11/2006)|
|9.||Rahman, Shamima: 5 articles (07/2015 - 05/2009)|
|10.||Littarru, G P: 5 articles (06/2010 - 04/2002)|
|1.||Friedreich Ataxia (Friedreich's Ataxia)
01/01/2003 - "Similarly, coenzyme Q(10) is also effective in animal models and has shown promising effects both in clinical trials of PD as well as in clinical trials in Huntington's disease and Friedreich's ataxia. "
05/01/2009 - "Idebenone is a synthetic analogue of ubiquinone that may be beneficial in the treatment of Friedreich's ataxia. "
03/10/2009 - "Idebenone, an artificial ubiquinone showing promise in the treatment of Friedreich's Ataxia, reacts at the flavin site. "
09/01/2008 - "Idebenone, a synthetic analogue of coenzyme Q, is a powerful antioxidant that was first administrated to Friedreich's ataxia patients less than 10 years ago. "
12/01/2008 - "A pilot study of high dose coenzyme Q(10) (CoQ(10))/vitamin E therapy in Friedreich's ataxia (FRDA) patients resulted in significant clinical improvements in most patients. "
02/01/2007 - "This compound has proven itself in pre-clinical models to be an efficient anti-cancer agent, targeting complex II of the respiratory chain to displace ubiquinone binding. "
01/01/2003 - "Furthermore coenzyme Q supplementation significantly lowered cell growth of the PC3 cancer line without affecting the PNT2. "
12/01/1974 - "The potential of coenzyme Q 10 (NSC-140865) in cancer treatment."
02/01/1973 - "(ii) Treatment with coenzyme Q(10) reduced the percentage of mice with tumors, increased the number of survivors, and reduced the tumor size in mice with tumors induced by 3,4,9,10-dibenzpyrene. "
02/01/1971 - "Ubiquinone and nucleic acid concentrations in the heart muscle of cancer patients and normal controls."
01/01/1975 - "Significant increases in the deficiency of coenzyme Q-enzyme activity were found in the spleen and blood of infected animals as the infection progressed. "
01/01/1975 - "The development of the deficiency and splenomegaly during infection seemingly correlate with previous data which showed that administration of coenzyme Q resulted in a reversal of splenomegaly and a reduction in mortality. "
01/01/1975 - "Coenzyme Q deficiency in mice following infection with Friend leukemia virus."
02/01/1973 - "Effect of stimulation of the host defense system by coenzyme Q 10 on dibenzpyrene-induced tumors and infection with Friend leukemia virus in mice."
06/01/2007 - "The aim of this study was to assess brain levels of coenzyme Q (CoQ), an endogenous lipophilic antioxidant, and the antioxidant/pro-oxidant status by determining oxidative damage to proteins and lipids after intracerebral bovine spongiform encephalopathy (BSE) infection of transgenic mice expressing bovine prion protein (PrP). "
|4.||Myocardial Ischemia (Ischemic Heart Diseases)
07/01/1990 - "Co-enzyme Q10 (ubiquinone) is a naturally occurring substance which has properties potentially beneficial for preventing cellular damage during myocardial ischemia and reperfusion. "
05/01/1996 - "Coenzyme Q10 (CoQ10, ubiquinone) has been shown to be protective against myocardial ischemia/reperfusion induced injury. "
05/01/2002 - "Coenzyme Q10 (CoQ10) or ubiquinone, a redox component of the mitochondrial electron transport chains, is a powerful antioxidant and membrane stabilizer that may prevent cellular damage during myocardial ischemia and reperfusion therapy. "
04/01/2000 - "To examine whether nutritional supplementation of coenzyme Q(10) (CoQ(10)) can reduce myocardial ischemia-reperfusion injury, a group of swine was fed a regular diet supplemented with CoQ(10) (5 mg x kg(-1) x day(-1)) for 30 days. "
01/01/1992 - "Plasma ubiquinone, coenzyme Q10 or CoQ10 has been analyzed in plasma together with alpha-tocopherol and free cholesterol in healthy sedentary male subjects (SS), endurance trained male athletes (ET) and male patients with severe ischemic heart disease (IHD). "
|5.||Leigh Disease (Leigh's Disease)
01/01/2007 - "Coenzyme Q(10) (CoQ) deficiency is an autosomal recessive disorder presenting five phenotypes: a myopathic form, a severe infantile neurological syndrome associated with nephritic syndrome, an ataxic variant, Leigh syndrome and a pure myopathic form. "
07/01/2009 - "Three representative cases have been selected: one with COX deficiency and a Leigh syndrome due to a SURF1 gene mutation, one due to a defect of Coenzyme Q synthesis and one with dominant optic atrophy due to a mutation in the OPA1 gene. "
07/01/2015 - "With the exception of a few rare vitamin/cofactor responsive conditions (including ACAD9 deficiency, disorders of coenzyme Q(10) biosynthesis, and Leigh syndrome caused by mutations in the SLC19A3 transporter), the mainstay of treatment for the vast majority of patients involves supportive measures. "
01/01/1990 - "Two infants who had clinical and radiographic findings consistent with Leigh syndrome were found to have deficiency of complex I (reduced nicotinamide-adenine dinucleotide--coenzyme Q reductase) activity. "
01/01/1990 - "Complex I (reduced nicotinamide-adenine dinucleotide-coenzyme Q reductase) deficiency in two patients with probable Leigh syndrome."
|1.||coenzyme Q10 (CoQ10)
|3.||Drug Therapy (Chemotherapy)
|4.||Continuous Positive Airway Pressure