Spinal Tuberculosis (Pott's Disease)

Osteitis or caries of the vertebrae, usually occurring as a complication of tuberculosis of the lungs.
Also Known As:
Pott's Disease; Tuberculosis, Spinal; Disease, Pott; Disease, Pott's; Potts Disease; Spinal Tuberculoses; Tuberculoses, Spinal; Pott Disease
Networked: 301 relevant articles (29 outcomes, 44 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Congenital Abnormalities (Deformity)
2. Kyphosis
3. Tuberculosis (Tuberculoses)
4. Infection
5. Wounds and Injuries (Trauma)


1. Wang, Zili: 7 articles (04/2015 - 11/2007)
2. Wang, Xiyang: 7 articles (01/2015 - 06/2013)
3. Guo, Chaofeng: 6 articles (01/2015 - 03/2013)
4. Zhang, Hongqi: 6 articles (01/2015 - 03/2013)
5. Pang, Xiaoyang: 6 articles (07/2014 - 06/2013)
6. Chen, Xing: 6 articles (11/2010 - 05/2009)
7. Zhang, Hong-Qi: 5 articles (08/2015 - 01/2008)
8. Li, Jing: 5 articles (06/2015 - 11/2009)
9. Tang, Mingxing: 5 articles (01/2015 - 03/2013)
10. Shen, Xiongjie: 5 articles (01/2015 - 06/2013)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Spinal Tuberculosis:
1. Isoniazid (Ftivazide)FDA LinkGeneric
2. Rifampin (Rifampicin)FDA LinkGeneric
3. TitaniumIBA
4. Ethambutol (Myambutol)FDA LinkGeneric
5. OxygenIBA
6. PyrazinamideFDA LinkGeneric
11/01/2008 - "The concentration levels of isoniazid, rifampin and pyrazinamide varied greatly in different tissues of spinal tuberculosis, of which the bactericidal concentration values of isoniazid and rifampin and fivefold minimal inhibitory concentration (MICs) of pyrazinamide were found in subnormal vertebral bone and self-contrast ilium, the MICs of all drugs were found in sclerotic wall outside foci, and undetected level was found in foci inside the sclerotic wall. "
03/01/2002 - "Inclusion criteria for publications: diagnosis of spinal tuberculosis confirmed bacteriologically and/or histologically, or probable on the basis of clinical and radiological parameters; treatment regimen (whether or not in combination with surgery) included isoniazid (H), rifampicin (R) and pyrazinamide (Z); follow-up period after completion of treatment of 12 months or more. "
11/01/2008 - "This is an experimental study on the distribution of antituberculosis drugs such as rifampin, isoniazid, and pyrazinamide in pathologic vertebrae of spinal tuberculosis in order to provide the regimen of chemotherapy and surgical treatment of spinal tuberculosis. "
05/01/2015 - "The patient was preliminarily diagnosed with miliary tuberculosis (TB) and Pott's disease, and began administering anti-TB treatment consisting of isoniazid, rifampin, ethambutol, and pyrazinamide. "
06/01/1986 - "Results are presented of the incidence of hepatitis, nearly always with jaundice, among 1686 patients in clinical trials of the treatment of spinal tuberculosis, of tuberculosis meningitis and of pulmonary tuberculosis with short-course regimens containing rifampicin, isoniazid, streptomycin and pyrazinamide. "
7. Streptomycin (Streptomycin Sulfate)FDA Link
8. DNA (Deoxyribonucleic Acid)IBA
9. Matrix MetalloproteinasesIBA
10. C-Reactive ProteinIBA

Therapies and Procedures

1. Debridement
2. Drug Therapy (Chemotherapy)
3. Bone Transplantation (Bone Grafting)
4. Decompression
5. Transplants (Transplant)