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Meningeal Tuberculosis (Tuberculous Meningitis)

A form of bacterial meningitis caused by MYCOBACTERIUM TUBERCULOSIS or rarely MYCOBACTERIUM BOVIS. The organism seeds the meninges and forms microtuberculomas which subsequently rupture. The clinical course tends to be subacute, with progressions occurring over a period of several days or longer. Headache and meningeal irritation may be followed by SEIZURES, cranial neuropathies, focal neurologic deficits, somnolence, and eventually COMA. The illness may occur in immunocompetent individuals or as an OPPORTUNISTIC INFECTION in the ACQUIRED IMMUNODEFICIENCY SYNDROME and other immunodeficiency syndromes. (From Adams et al., Principles of Neurology, 6th ed, pp717-9)
Also Known As:
Tuberculous Meningitis; Tuberculosis Meningitis; Tuberculosis, Meningeal; TB Meningitis; Tubercular Meningitis; Tuberculous Hypertrophic Pachymeningitis; Hypertrophic Pachymeningitides, Tuberculous; Hypertrophic Pachymeningitis, Tuberculous; Meningeal Tuberculoses; Meningitides, Tubercular; Meningitides, Tuberculosis; Meningitides, Tuberculous; Meningitis, Tubercular; Meningitis, Tuberculosis; Pachymeningitides, Tuberculous Hypertrophic; Pachymeningitis, Tuberculous Hypertrophic; TB Meningitides; Tubercular Meningitides; Tuberculoses, Meningeal; Tuberculosis Meningitides; Tuberculous Hypertrophic Pachymeningitides; Tuberculous Meningitides; Meningitis, Tuberculous
Networked: 2559 relevant articles (106 outcomes, 203 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Miliary Tuberculosis
2. Hydrocephalus (Hydrocephaly)
3. Tuberculosis (Tuberculoses)
4. Pulmonary Tuberculosis
5. Tuberculous Pericarditis

Experts

1. Thwaites, Guy E: 36 articles (01/2022 - 10/2003)
2. Boulware, David R: 17 articles (09/2022 - 12/2013)
3. Kalita, Jayantee: 14 articles (08/2022 - 05/2008)
4. van Crevel, Reinout: 14 articles (01/2021 - 01/2013)
5. Ruslami, Rovina: 13 articles (01/2022 - 01/2013)
6. Farrar, Jeremy J: 13 articles (01/2016 - 10/2003)
7. Cresswell, Fiona V: 12 articles (09/2022 - 01/2018)
8. Wolbers, Marcel: 12 articles (01/2020 - 01/2011)
9. Caws, Maxine: 11 articles (01/2022 - 03/2004)
10. Wilkinson, Robert J: 11 articles (05/2021 - 12/2013)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Meningeal Tuberculosis:
1. Streptomycin (Streptomycin Sulfate)FDA Link
2. BCG VaccineFDA Link
3. Rifampin (Rifampicin)FDA LinkGeneric
4. SteroidsIBA
5. Isoniazid (Ftivazide)FDA LinkGeneric
6. Adrenal Cortex Hormones (Corticosteroids)IBA
7. Adenosine DeaminaseIBA
8. VaccinesIBA
9. Linezolid (Zyvox)FDA Link
10. Levofloxacin (Levaquin)FDA Link

Therapies and Procedures

1. Therapeutics
2. Drug Therapy (Chemotherapy)
3. Ventriculoperitoneal Shunt
4. Ventriculostomy
5. Critical Care (Surgical Intensive Care)