Tryptophan Synthase (Synthase, Tryptophan)
An enzyme that catalyzes the conversion of L-serine and 1-(indol-3-yl)glycerol 3-phosphate to L-tryptophan and glyceraldehyde 3-phosphate. It is a pyridoxal phosphate protein that also catalyzes the conversion of serine and indole into tryptophan and water and of indoleglycerol phosphate into indole and glyceraldehyde phosphate. (From Enzyme Nomenclature, 1992) EC 4.2.1.20.
Also Known As:
Synthase, Tryptophan; Synthetase, Tryptophan; Tryptophan Synthetase; L-Serine hydro-lyase (adding indoleglycerol-phosphate)
Networked: 11
relevant articles (0 outcomes,
0 trials/studies)
Bio-Agent Context: Research Results
Experts
1. | Belland, Robert J:
2 articles
(01/2014 - 06/2003)
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2. | Caldwell, Harlan D:
2 articles
(07/2005 - 06/2003)
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3. | McClarty, Grant:
2 articles
(07/2005 - 06/2003)
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4. | Roshick, Christine:
2 articles
(07/2005 - 06/2003)
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5. | Wood, Heidi:
2 articles
(07/2005 - 06/2003)
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6. | Chang, Changsoo:
1 article
(01/2020)
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7. | Gusovsky, Fabian:
1 article
(01/2020)
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8. | Jedrzejczak, Robert:
1 article
(01/2020)
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9. | Joachimiak, Andrzej:
1 article
(01/2020)
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10. | Maltseva, Natalia I:
1 article
(01/2020)
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Related Diseases
1. | Tuberculosis (Tuberculoses)
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2. | Starvation
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3. | Infections
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4. | Dehydration (Water Stress)
01/26/1993
- " Tryptophan synthase also catalyzes the dehydration of serine, or 3-fluoroalanine, to pyruvate in the absence of indole. " 10/01/2023
- " Expression of chorismate mutase regulates phenylalanine biosynthesis, UV light and drought stress-responsive genes, e.g., phenylalanine ammonia lyase (OsPAL), dehydrin (OsDHN), dehydration-responsive element-binding (OsDREB), ras-related protein 7 (OsRab7), ultraviolet-B resistance 8 (OsUVR8), WRKY transcription factor 89 (OsWRKY89) and tryptophan synthase alpha chain (OsTSA). "
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5. | Vitamin B 6 Deficiency (Pyridoxine Deficiency)
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