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African Trypanosomiasis (Nagana)

A disease endemic among people and animals in Central Africa. It is caused by various species of trypanosomes, particularly T. gambiense and T. rhodesiense. Its second host is the TSETSE FLY. Involvement of the central nervous system produces "African sleeping sickness." Nagana is a rapidly fatal trypanosomiasis of horses and other animals.
Also Known As:
Nagana; Trypanosomiasis, African; African Sleeping Sicknesses; African Trypanosomiases; Sickness, African Sleeping; Sicknesses, African Sleeping; Sleeping Sickness, African; Sleeping Sicknesses, African; Trypanosomiases, African; African Sleeping Sickness
Networked: 716 relevant articles (29 outcomes, 51 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Trypanosomiasis
2. Leishmaniasis
3. Chagas Disease (American Trypanosomiasis)
4. African Trypanosomiasis (Nagana)
5. Malaria

Experts

1. Barrett, Michael P: 22 articles (03/2015 - 01/2002)
2. Brun, Reto: 22 articles (02/2015 - 06/2003)
3. Gilbert, Ian H: 17 articles (11/2015 - 07/2003)
4. Ferguson, Michael A J: 17 articles (12/2014 - 04/2002)
5. Fairlamb, Alan H: 15 articles (12/2014 - 06/2003)
6. Kaiser, Marcel: 13 articles (02/2014 - 08/2007)
7. Boykin, David W: 12 articles (02/2015 - 04/2004)
8. Krauth-Siegel, R Luise: 12 articles (11/2013 - 03/2002)
9. Frearson, Julie A: 11 articles (11/2015 - 07/2009)
10. Wyatt, Paul G: 11 articles (11/2015 - 07/2009)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to African Trypanosomiasis:
1. Eflornithine (Ornidyl)FDA Link
2. Pentamidine (NebuPent)FDA LinkGeneric
3. Melarsoprol (Mel B)IBA
4. NifurtimoxIBA
5. Suramin (Suramin Sodium)IBA
6. furamidine (DB75)IBA
7. furanIBA
8. fexinidazoleIBA
9. DNA (Deoxyribonucleic Acid)IBA
10. Membrane Glycoproteins (Membrane Glycoprotein)IBA

Therapies and Procedures

1. Drug Therapy (Chemotherapy)
2. Combination Drug Therapy (Combination Chemotherapy)
3. Aftercare (After-Treatment)
4. Therapeutics
5. Oral Administration