|1.||Skellern, G G: 2 articles (12/2014 - 12/2002)|
|2.||Clausen, Peter-Henning: 2 articles (01/2012 - 10/2010)|
|3.||Zessin, Karl-Hans: 2 articles (01/2012 - 10/2010)|
|4.||Bauer, Burkhard: 2 articles (01/2012 - 10/2010)|
|5.||Diall, Oumar: 2 articles (01/2012 - 10/2010)|
|6.||Geerts, S: 2 articles (06/2001 - 01/2001)|
|7.||Eisler, M C: 2 articles (06/2001 - 01/2001)|
|8.||Holmes, P H: 2 articles (06/2001 - 01/2001)|
|9.||Moroni, Samanta: 1 article (06/2015)|
|10.||García-Bournissen, Facundo: 1 article (06/2015)|
01/01/1983 - "Mice infected with Trypanosoma brucei can be easily cured using the available trypanocidal drugs, provided treatment is given soon after the infection; however, if infection is allowed to continue for some time then it is extremely difficult to obtain a permanent cure, and after an aparasitaemic period the infection eventually relapses. "
06/12/2001 - "Finally, we describe tests in cattle that may be used to determine the efficacy of recommended curative doses of trypanocidal drugs for the treatment of infection with individual trypanosome isolates, including Trypanosoma vivax, which is rarely infective for mice."
01/01/2012 - "Study investigated and compared, in an experimental Trypanosoma infection, the effects of two trypanocides on the pathology of tissues and some biochemical indices in rats. "
11/01/1995 - "These cattle were treated with trypanocidal drugs following each infection and had remained aparasitemic for 3 years prior to this study. "
12/01/1988 - "Limited studies have been undertaken on the treatment of infections with trypanosomes of the subgenus Herpetosoma, either in comparative studies on the effects of trypanocidal drugs or as potential non-pathogenic models for evaluating trypanocidal activities. "
10/15/1980 - "I. A study of trypanosomiasis occurrence and the use of trypanocidal agents]."
01/01/2012 - "Modeling the control of trypanosomiasis using trypanocides or insecticide-treated livestock."
02/18/2006 - "In large parts of Africa the control of livestock trypanosomiasis relies on the use of trypanocidal drugs. "
04/01/2003 - "One third of drug treatments given to sick cattle were trypanocides, but over half of these trypanocidal treatments were given to cattle believed to have diseases other than trypanosomiasis."
03/01/2002 - "When presented with four different trypanosomiasis control methods, community representatives selected 'better use of trypanocides' as the most preferred intervention and 'community-based tsetse control' as the least preferred intervention. "
|3.||African Trypanosomiasis (Nagana)
04/01/2011 - "rhodesiense the population parameters for tsetse - species composition, survival and abundance - were ranked almost as highly as the proportion refractory, and that the model assumed regular treatment of livestock with trypanocides as an established practice in the areas of Uganda experiencing East African sleeping sickness."
10/01/2010 - "Nagana is routinely controlled by the use of trypanocides and an overreliance on their use throughout past decades resulted in multiple drug resistance of trypanosomes in most parts of West Africa's cotton belt. "
09/01/2009 - "The involvement of purine salvage in the accumulation of current trypanocidal drugs is important for the treatment of African sleeping sickness. "
06/01/2003 - "Considering both, lack of toxicity and inhibitory activity, D-carnitine may have a role in the treatment of African trypanosomiasis, in association with available trypanocidal drugs."
11/01/1984 - "Since: 1) DFMO has very low toxicity, 2) suramin is one of the least toxic of the presently used trypanocides, and 3) suramin and DFMO act synergistically in mouse models of both acute and late stage trypanosomiasis, we conclude that this combination offers special promise in the treatment of African trypanosomiasis in man."
|4.||Chagas Disease (American Trypanosomiasis)
03/01/2013 - "Artificial neural networks based on CODES descriptors in pharmacology: identification of novel trypanocidal drugs against Chagas disease."
02/01/2013 - "Although new, more effective and better tolerated compounds are urgently needed, treatment with these trypanocidal drugs is recommended in both the acute and chronic stages of Chagas disease. "
06/01/2011 - "cruzi and are also potential trypanocidal agents to prevent transfusion-associated Chagas' disease."
01/01/2005 - "Trypanocidal drugs for late stage, symptomatic Chagas disease (Trypanosoma cruzi infection)."
12/31/2013 - "This enzyme is clinically relevant due to its role in the action mechanism of some trypanocidal drugs used in the treatment of Chagas' disease by producing reactive oxygen species. "
|1.||Suramin (Suramin Sodium)
|7.||isometamidium chloride (ISMM)
|8.||Reactive Oxygen Species (Oxygen Radicals)
|2.||Combination Drug Therapy (Combination Chemotherapy)