HOME PRODUCTS SERVICES COMPANY CONTACT FAQ

Tropicamide

Subscribe to New Research on Tropicamide

One of the MUSCARINIC ANTAGONISTS with pharmacologic action similar to ATROPINE and used mainly as an ophthalmic parasympatholytic or mydriatic.

Also Known As:

Akorn Brand of Tropicamide; Alcon Brand of Tropicamide; Bournonville Brand of Tropicamide; Cahill May Roberts Brand of Tropicamide; Chauvin Brand of Tropicamide; Colircusi Tropicamida; Medical Ophthalmics Brand of Tropicamide; Minims Tropicamide; Mydral; Mydriafair; Mydriaticum; Mydrum; N-Ethyl-N-(4-pyridylmethyl)tropamide; N-Ethyl-alpha-(hydroxymethyl)-N-(4-pyridinylmethyl)benzeneacetamide; Novartis Brand of Tropicamide; Ocu-Tropic; Ocumed Brand of Tropicamide; Ocusoft Brand of Tropicamide; Pharmafair Brand of Tropicamide; Rivex Brand of Tropicamide; Stulln Brand 1 of Tropicamide; Stulln Brand 2 of Tropicamide; Triaminic DM; Tropicacyl; Tropicamide Faure; Tropicamide Minims; Tropicamide Monofree; Tropicamide Monohydrochloride, (R)-Isomer; Tropicamide Monohydrochloride, (S)-Isomer; Tropicamide, (+-)-Isomer; Tropicamide, (R)-Isomer; Tropicamide, (S)-Isomer; Ocu Tropic; OcuTropic; Tropicamide Alcon Brand; Tropicamide Chauvin Brand; Tropicamide Novartis Brand; Tropicamide Ocumed Brand; Tropicamide Pharmafair Brand; Tropicamide Rivex Brand; Benzeneacetamide, N-ethyl-alpha-(hydroxymethyl)-N-(4-pyridinylmethyl)-

Networked: 152 relevant articles (10 outcomes, 19 trials/studies) for this Drug, Comments

Relationship Network

Drug Context: Research Results

Heterocyclic Compounds: 25
- 1-Ring Heterocyclic Compounds
  - Pyridines: 30
    - Tropicamide: 152
      - phenyltrope: 1
      - N-ethyl-2-phenyl-N-(4-pyridylmethyl)prop-2-enamide

Experts

1.	Mutti, Donald O: 3 articles (03/2009 - 11/2002)
2.	Tokuda, Kazuhiro: 3 articles (02/2005 - 10/2002)
3.	Miyazaki, Yasunori: 3 articles (02/2005 - 10/2002)
4.	Matsubara, Masao: 3 articles (02/2005 - 10/2002)
5.	Kamei, Yuko: 3 articles (02/2005 - 10/2002)
6.	Hirowatari, Takao: 3 articles (02/2005 - 10/2002)
7.	Norton, Thomas T: 3 articles (07/2004 - 02/2002)
8.	Hyman, Leslie: 3 articles (07/2004 - 02/2002)
9.	Varughese, Sara: 2 articles (01/2009 - 06/2005)
10.	Varghese, Raji Mathew: 2 articles (01/2009 - 06/2005)

Related Diseases

1.	Mydriasis 06/01/2010 - "The mean onset of mydriasis after instillation of 1% tropicamide ophthalmic solution was 16.7 +/- 3.34 min and the mean duration of effect was 17.6 +/- 8.26 hr. The data obtained in this investigation will aid veterinary ophthalmologists and zoo veterinarians to diagnose ocular diseases in the red kangaroo accurately." 07/01/2009 - "The mean pupillary diameter 30 min after the application of tropicamide ranged from 2.5 mm (SD = 0.16) in female F1 to 3.0 mm (SD = 0.13) in male C57BL/6. Tropicamide produced a sexual dimorphism in mydriasis for all mice (F = 56.30, dF = 1, 59, p < 0.001); however, strain-dependent differences were not observed (F = 1.31, dF = 2, 59, p < 0.280). " 05/01/2007 - "Does prior instillation of a topical anaesthetic alter the pupillary mydriasis produced by tropicamide (0.5%)?" 04/01/2006 - "Intraocular pressure change following application of 1% tropicamide for diagnostic mydriasis." 02/01/2003 - "PURPOSE: To compare the mydriatic effect and safety between different concentrations of tropicamide and phenyle-phrine in preoperative mydriasis for phaco-emulsification. " Order ALL the reference details at left...
2.	Alzheimer Disease (Alzheimer's Disease) 06/01/1997 - "CONCLUSION: Results of this study indicate that pupil measurement after instillation of tropicamide cannot be used as a reliable diagnostic test for Alzheimer's disease. " 06/01/1996 - "We performed a masked study involving 17 patients with Alzheimer's disease and 20 mentally healthy controls with respect to the pupillary response induced by tropicamide. " 02/01/2008 - "Previous research demonstrated that it is possible to distinguish patients with probable Alzheimer's disease from age-matched controls based on an exaggerated pupil dilation response to dilute tropicamide. " 01/01/2006 - "RATIONALE: Patients suffering from Alzheimer's disease (AD) may show increased sensitivity to tropicamide, a muscarinic cholinoceptor antagonist. " 10/01/2003 - "Re-evaluation of tropicamide in the pupillary response test for Alzheimer's disease." Order ALL the reference details at left...
3.	Cataract (Cataracts) 02/01/2009 - "CONCLUSION: When combined with 1 drop of tropicamide 1% preoperatively, both formulations provided safe and effective intracameral dilation for cataract surgery; however, the epi-S solution was the more efficacious at each step of the procedure." 03/01/2000 - "Effect of tropicamide on aqueous flare before and after cataract surgery." 04/01/1996 - "The AL of one eye of 64 patients admitted for cataract surgery was measured before and after dilation with a drop of tropicamide 1%. " 04/01/1998 - "CONCLUSION: Pupil dilation with 10% phenylephrine alone, if allowed at least 40 minutes to act, will be as satisfactory for the identification of cataracts in a normal population as 10% phenylephrine and 1% tropicamide and is more acceptable because of reduced problems with glare and accommodation." 04/01/1998 - "Pupils were dilated with phenylephrine alone for cataract identification because there were concerns that patient discomfort, due to cycloplegia occurring with the usual dilating agents of tropicamide and phenylephrine, may influence future compliance in an associated intervention study. " Order ALL the reference details at left...
4.	Refractive Errors (Refractive Error) 03/01/2009 - "Accommodative response was measured by MEM and PR at 33 and 57 cm, acuity by Teller Acuity Cards, and cycloplegic refractive error (RE) (tropicamide 1%) by retinoscopy (Wet Ret) and PR (PR C). " 02/01/1984 - "The pre- and post-test refractive errors at distance were determined using 1% tropicamide HCl. " 04/01/2001 - "CONCLUSION: Our results suggest that tropicamide is as effective as cyclopentolate for the measurement of refractive error in most healthy, nonstrabismic infants." 12/01/2003 - "The refractive error was determined using cyclopentolate and tropicamide as cycloplegic agents and compared to that determined in a non-cycloplegic situation. " 04/01/2001 - "The mean refractive error was +1.81 D (+/-1.19 D) with tropicamide and +1.88 D (+/-1.45 D) with cyclopentolate. " Order ALL the reference details at left...
5.	Vascular Dementia (Subcortical Arteriosclerotic Encephalopathy) 03/01/1997 - "The anticholinergic agent tropicamide causes a significantly greater change in the pupil diameter of patients with Alzheimer's disease (AD) than in that of patients with alcoholic or vascular dementia or in normal controls. " 09/01/1998 - "We tested the pupillary response to the instillation of 0.01% tropicamide in 48 subjects: 15 patients with probable or possible Alzheimer's disease, five patients with vascular dementia (VD), 16 elderly controls (EC) and 12 young controls (YC). " 03/01/1997 - "Pupillary response to tropicamide in Japanese patients with alcoholic dementia, Alzheimer's disease, and vascular dementia." 10/01/2003 - "When the tropicamide concentration was diluted to half of the initial concentration and performed for AD (n=14), vascular dementia (VD) (n=14), and young (n=16) subjects, the AD subjects showed a large dilation (mean pupil dilation rate: 133.8+/-15%) while the non-AD subjects did not show hypersensitivity to the new concentration of eye drops (105.4+/-9%). " Order ALL the reference details at left...

Related Drugs and Biologics

1.	Phenylephrine (Neo-Synephrine)
2.	Cyclopentolate (Cyclogyl)
3.	dapiprazole (Rev-Eyes)
4.	ibopamine
5.	Ophthalmic Solutions (Eye Drops)
6.	Fluorescein (Funduscein)
7.	Muscarinic Antagonists
8.	Atropine (Hyoscyamine)
9.	Cholinergic Antagonists (Anticholinergics)
10.	p-Hydroxyamphetamine (Hydroxyamfetamine)

Related Therapies and Procedures

1.	Premedication
2.	Cataract Extraction
3.	Meridians (Jing Luo)
4.	Lasers (Laser)
5.	Anesthesia

blog comments powered by Disqus

TREATMENT OPTIONS
for Mydriasis,
Ranking and Evidence

*WARNING* This specific disease subtype has a relatively small number of significant evidence outcomes. You may proceed to order anyway, or go back to the search field and enter a more general type of the target illness. Once your report has been ordered, however, we can't refund the purchase.

CureHunter Patient-Physician Summary Reports collect in one document all the medications ever reported in the US National Library of Medicine—1949 to the present—to be effective against your target disease. Analytic charts allow you and your physicians to see at a glance the treatment options—including new, promising, off-label and experimental.

Free Updates for 1 Year
All 37 Outcomes
Top 200 Key Drugs and Biologics
Top 50 Key Therapies and Procedures
Detailed History Charts
Full Research Evidence References
Sample PDF Report on Psoriasis >>

Price:

$8.50 USD & Delivery via PDF download
updates for 1 year

Research Interface PRO

Rapidly retrieve clinical outcome summaries for all evidence of drug efficacy against any disease in seconds. Click "Charts" to view graphs of relative efficacy of all drugs against any known disease. CureHunter is unlike any "search engine" you have ever used. Where standard "search engines" produce lists of links, CureHunter quantifies evidence, extracts it from the literature and calculates a result you can use to immediately facilitate evidence based decision making in Real Clinical Time. Save hours of search and analysis time:

Two-clicks from Disease to Drug to Evidence: Drill down to full abstract
Enable Experts: Quickly identify key researchers and their publications
Enable FDA Link Generic: Two-clicks to FDA Products/Patents/Generics
Enable Export: All outcome statements and scores exportable to Excel/TSV for automated meta-analysis
Research Network: Explore drug and disease relationships visually
Enable Mobile Interface: Access from your cellphone, iPhone or PDA

Price:

$45.00 USD access via web interface
1 year subscription

Request Bulk Institution License Details >>