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Trimethoprim (Proloprim)

1470  relevant articles (152 outcomes, 156 trials/studies) found for this Drug

Description: A pyrimidine inhibitor of dihydrofolate reductase, it is an antibacterial related to PYRIMETHAMINE. The interference with folic acid metabolism may cause a depression of hematopoiesis. It is potentiated by SULFONAMIDES and the TRIMETHOPRIM-SULFAMETHOXAZOLE COMBINATION is the form most often used. It is sometimes used alone as an antimalarial. TRIMETHOPRIM RESISTANCE has been reported.

Also Known As:
Proloprim; Trimpex; 2,4-Pyrimidinediamine, 5-((3,4,5-trimethoxyphenyl)methyl)-

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Drug Context: Research Results