|1.||Majnooni, Mohammad Bagher: 1 article (01/2013)|
|2.||Franzese, O: 1 article (01/2013)|
|3.||Aquino, A: 1 article (01/2013)|
|4.||Bianchi, A: 1 article (01/2013)|
|5.||Marchesi, F: 1 article (01/2013)|
|6.||Margison, G P: 1 article (01/2013)|
|7.||Lattuada, D: 1 article (01/2013)|
|8.||Bonmassar, E: 1 article (01/2013)|
|9.||Mostafaie, Ali: 1 article (01/2013)|
|10.||Bonmassar, L: 1 article (01/2013)|
01/01/1996 - "(Methylcarbamoyl)triazenes have been shown to be effective cancer chemotherapeutic agents in a number of biological systems. "
01/01/2013 - "The synthesized triazenes showed marked cytotoxicity effects on all eight cancer cell lines. "
10/24/2002 - "The spin labeled triazenes were mainly localized in the tumor and in the brain. "
07/01/1984 - "Tumor inhibitory triazenes. "
03/01/1984 - "The (hydroxymethyl)triazenes have pronounced antitumor activity against the TLX5 tumor in vivo; in vivo-in vitro bioassay experiments suggest that the (hydroxymethyl)triazenes exert their in vivo antitumor activity via the degradation product, the alkyltriazene."
|2.||Melanoma (Melanoma, Malignant)
04/01/1984 - "In vitro cytotoxicity of a series of antitumour triazenes towards the M21 melanoma cell line has been studied. "
01/01/1986 - "Although dacarbazine and related cytostatic triazenes are effective in the treatment of malignant melanoma and other human malignancies, dacarbazine has been demonstrated to be a carcinogen in laboratory rodents. "
01/01/2013 - "The present paper describes several studies of leukemia treatment with triazenes and a case of acute refractory leukemia with massive skin infiltration by malignant cells. "
08/01/1997 - "Previous studies suggested that methylating triazenes might have a potential role for the treatment of acute leukemias with low levels of OGAT. "
01/01/2013 - "In view of their potential activity as CX inducers, triazenes could offer the additional advantage of host anti-leukemia immune responses. "
03/01/1956 - " VII. Effect of substituted triazenes on transplanted mouse leukemia."
08/01/1997 - "This study also supports the possible use of TZM for the treatment of acute leukemias and suggests new strategies to increase the susceptibility of tumor cells to methylating triazenes in the clinic."
|4.||Lewis Lung Carcinoma
01/01/1980 - "Antitumor and antimetastatic effects of benzenoid triazenes in mice bearing Lewis lung carcinoma."
01/01/1995 - "The involvement of protein kinase c (PKC) in the mechanism underlying the antimetastatic properties of triazenes was studied in C57BL/6 mice bearing Lewis lung carcinoma (3LL). "
10/24/2002 - "Normal leucocites, YAC-1 mNK target Moloney lymphoma cells and B16 melanoma cells were treated with spin labeled triazenes in vitro and the effects on cell viability were compared. "
10/24/2002 - "Tissue distribution of the triazenes was investigated in vitro in organ homogenates, tumor (B16 melanoma) and blood of C57BL mice using the electron paramagnetic resonance (EPR) method. "
01/16/2001 - "A higher cytotoxicity to B16 melanoma cells than to YAC-1 and lymphocytes was demonstrated for all spin labeled triazenes, in comparison with DTIC. "
|2.||DNA (Deoxyribonucleic Acid)
|4.||Mesna (Coenzyme M)
|7.||Epidermal Growth Factor Receptor (EGF Receptor)
|8.||Protein Kinase C