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Tretoquinol
An adrenergic beta-agonist used as a bronchodilator agent in asthma therapy.
Also Known As:
AQ-110; AQL-208; CV-705; Tetroquinol; Tretoquinol Hydrochloride; Tretoquinol Hydrochloride Anhydrous; Tretoquinol Hydrochloride, (S)-Isomer; Tretoquinol-(R); Tretoquinol-(S) HCl; Trimetoquinol; AQ 110; AQ110; AQL 208; AQL208; CV 705; CV705; Trimethoquinol; 6,7-Isoquinolinediol, 1,2,3,4-tetrahydro-1-((3,4,5-trimethoxyphenyl)methyl)-, (S)-
Networked:
5
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Heterocyclic Compounds: 198
Fused-Ring Heterocyclic Compounds
2-Ring Heterocyclic Compounds
Isoquinolines: 34
Benzylisoquinolines: 151
Tretoquinol: 5
1-(3',4'-dihydroxybenzyl)-1,2,3,4-tetrahydroisoquinoline: 3
1-benzyl-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline: 1
1-(2',4',5-trimethoxybenzyl)-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline
1-(3,4,5-trimethoxybenzyl)-1,2,3,4-tetrahydroisoquinoline
1-(3,4,5-trimethoxybenzyl)-7-hydroxy-1,2,3,4-tetrahydroisoquinoline
5,7-dihydroxy-1-(3,4,5-trimethoxybenzyl)-1,2,3,4-tetrahydroisoquinoline
5-fluorotrimetoquinol
6,7-dihydroxy-1-(3,5-diiodobenzyl)-1,2,3,4-tetrahydroisoquinoline
8-fluorotrimetoquinol
Experts
1.
Iwase, Takeshi
: 1 article (01/2005)
2.
Ng, G Y
: 1 article (01/2001)
3.
Ohlsson, A
: 1 article (01/2001)
4.
da, S
: 1 article (01/2001)
Related Diseases
1.
Tachycardia (Tachyarrhythmias)
10/01/1981 - "
A pharmacological evaluation of the potential of a bronchodilator trimetoquinol to produce tachycardia and skeletal muscle tremor.
"
02/01/1976 - "
Norepinephrine (0.5-5 mug i.c.) caused a typical rise in blood pressure with no significant change in heart rate and a fall in blood pressure with a bradycardia, which were completely blocked after treatment with phentolamine (10-50 mug i.c.) L-isoproterenol (0.05-0.5 mug i.c.) and trimetoquinol (0.5-3 mug i.c.), a beta-sympathomimetic agent, usually caused a fall in blood pressure with a tachycardia, which was reduced after treatment with propranolol (10-50 mug i.c.), but trimetoquinol was inclined to cause a rise in blood pressure with a tachycardia.
"
2.
Tremor (Tremors)
10/01/1981 - "
A pharmacological evaluation of the potential of a bronchodilator trimetoquinol to produce tachycardia and skeletal muscle tremor.
"
3.
Lung Diseases (Lung Disease)
01/01/2001 - "
The following terms were used: bronchopulmonary dysplasia, chronic lung disease, bronchodilator agents, adrenergic agents, anticholinergic agents, albuterol, aminophylline, atropine, caffeine, clenbuterol, cromakalim, ephedrine, epinephrine, fenoterol, hexoprenaline, ipratropium, isoetharine, isoproterenol, orciprenaline, procaterol, terbutaline, theophylline, tretoquinol.
"
4.
Cataract (Cataracts)
01/01/2005 - "
Refractive change after YAG laser posterior capsulotomy was also evaluated in 2 groups (811 C RESULTS: Only the AQ 110 NV group demonstrated statistically significant myopic change, which gradually increased until 12 months after cataract surgery, and significant anterior shift of an IOL 3 months after surgery.
"
01/01/2005 - "
A silicone IOL (AQ 110 NV), but not HSM-PMMA or acrylic IOL, shifted anteriorly, resulting in myopic change after cataract surgery.
"
01/01/2005 - "
Postoperative refractive change was analyzed 1 week to 12 months after cataract surgery using an autorefractmeter in 4 patient groups implanted with 811 C (HSM-PMMA, 83 eyes), 824 C (HSM-PMMA, 80 eyes), AQ 110 NV (3-piece silicone, 191 eyes), and MA 60 BM (3-piece acrylic, 80 eyes).
"
5.
Bronchopulmonary Dysplasia
01/01/2001 - "
The following terms were used: bronchopulmonary dysplasia, chronic lung disease, bronchodilator agents, adrenergic agents, anticholinergic agents, albuterol, aminophylline, atropine, caffeine, clenbuterol, cromakalim, ephedrine, epinephrine, fenoterol, hexoprenaline, ipratropium, isoetharine, isoproterenol, orciprenaline, procaterol, terbutaline, theophylline, tretoquinol.
"
Related Drugs and Biologics
1.
Isoproterenol (Isoprenaline)
2.
Procaterol (Pro-Air)
3.
Bronchodilator Agents (Bronchodilators)
4.
Albuterol (Salbutamol)
5.
Polymethyl Methacrylate (Sol)
6.
Cromakalim (Levcromakalim)
7.
Cholinergic Antagonists (Anticholinergics)
8.
Adrenergic Agents (Adrenergic Drugs)
9.
Theophylline (Theon)
10.
Terbutaline (Brethaire)
Related Therapies and Procedures
1.
Posterior Capsulotomy
2.
Solid-State Lasers
3.
Aftercare (After-Treatment)