Treponemal Infections (Bejel)

01/01/2022 - "To our knowledge, this is the first study on blinded molecular biological monitoring of the therapeutic efficacy of SA with respect to treponemal infection, and on complete BDD M2-stage remission in all animals achieved by SA treatment according to an optimized protocol. "

09/01/2009 - "Treponemal infection has been shown to induce the appearance of antiphosphorylcholine antibodies. "
07/01/1979 - "These findings provide further evidence that induction of immune responses may be abnormal early in treponemal infection and may help to explain the failure of the host to produce antibodies which eradicate the organism during the first 2 to 3 months of infection."
01/01/1998 - "The most likely explanation for the high antitreponemic antibodies is endemic syphilis, or Bejel, which is increasing in this region. "
10/01/1978 - "Data indicate that anti-treponemal antibodies can be detected in the spinal fluid even in patients with no neurological symptoms in cases of secondary syphilis and that the FTA-CSF test can be a valuable tool in the early detection of an immunological response to treponemal infection in the spinal fluid."
01/01/2023 - "The presence of antibodies to both antigens ("double positive") likely reflects current or recent treponemal infection. "

01/01/1969 - "[Experimental studies on the masking effect of antibiotics on the course of treponemal infections]."
04/08/1978 - "In latent syphilis and in late and congenital cases, as well as in instances of other treponemal infections, serological evidence of disease needs to be considered along with each patient's medical, social and sexual history, when and why they may have been given antibiotic treatment, and the results of radiological studies and cerebrospinal fluid examination. "

02/01/1991 - "For this purpose, two groups of LL patients with similar clinical features and no evidence of treponemal infection were studied, one group with BFP (n = 21) and the other without BFP (n = 13). "
04/01/1995 - "Because some TSP patients have biological false positive tests for treponemal infections (BFP-STS), we used ELISA to study BFP-STS and anticardiolipin antibodies in 42 Jamaican TSP patients. "
02/01/1991 - "Within the wide range of immunological abnormalities occurring in lepromatous leprosy (LL), antiphospholipid antibodies unrelated to treponemal infection, the so-called biological false positive test for syphilis (BFP), have long been recognized. "

04/01/1995 - "Because some TSP patients have biological false positive tests for treponemal infections (BFP-STS), we used ELISA to study BFP-STS and anticardiolipin antibodies in 42 Jamaican TSP patients. "

10/01/1986 - "As part of a multidisciplinary study of the population of Bali, Indonesia, 2452 blood samples from people of both sexes were tested for treponemal infection and blood groups. "

05/01/1985 - "Although penicillin is the drug of choice for all treponemal infections, some individuals will be allergic to this drug. "
11/01/1968 - "Following clinical assessment of these serologically reactive patients, approximately one in 100 immigrant and one in 2,500 non-immigrant pregnant women examined in this series were treated with penicillin; this represented just over half the number of patients with serological evidence of a treponemal infection, a ratio which was similar for immigrant and native born women. "
05/01/1946 - "Preventive action of penicillin administered orally to mice subjected to treponemal infection."
05/01/1946 - "Preliminary note on the treatment of bejel with penicillin."
04/01/1951 - "MINIMUM penicillin therapy in the treatment of treponemal infections by WHO/UNICEF field teams."

04/01/2022 - "No sera with isolated IgM positivity (0/90) demonstrated seroconversion consistent with early treponemal infection, in contrast to 17% (2/12) of sera with isolated TPPA positivity. "
07/01/1989 - "Moreover, IgM antibody reactivity with decreased titres can be detected in the later stages of untreated treponemal infection. "
01/01/1976 - "[Role of IgM in treponemal infections and the usefulness of monovalent FTA-IgM test in serodiagnosis of syphilis]."
07/01/2013 - "IgM antibodies are usually the first to be produced during treponemal infection. "
01/01/1986 - "Specific immunoglobulin M and G antibodies in the rapid diagnosis of human treponemal infections."

12/01/1997 - "Among 1708 registered children aged 0-14, the 553 first attending were tested for treponemal infection with both rapid plasma reagin test (RPR) and Treponema pallidum Haemagglutination test (TPHA). "
04/01/1994 - "Recent treponemal infection, measured by the rapid plasma reagin test, was not associated with HIV-1 seropositivity in men or women. "
10/01/1992 - "Of 826 pregnant women studied in a rural area of The Gambia, 77 (9.3%) were seropositive for a treponemal infection (positive rapid plasma reagin [RPR] and Treponema pallidum hemagglutination [TPHA] test). "
06/01/1982 - "Only 8% exhibited false positive tests for reagin with a negative FTA-ABS and neither historical nor clinical evidence of treponemal infection. "
01/01/1955 - "The presence of reagin-like substances of extraneous origin to treponemal infection, as well as of reagin, in yaws patients may be responsible for some of these phenomena."

04/01/1989 - "Screening for treponemal infection by a new enzyme immunoassay."
01/01/2021 - "This case report, in line with other newly published reports, promotes awareness of SH as a rare manifestation of treponemal infection and highlights the importance of including SH in the differential diagnosis for patients at risk for sexually transmitted infections and presenting with liver enzyme abnormalities. "
12/01/2012 - "To evaluate the performance of two enzyme immunoassays (EIA), Murex and ICE, and the Determine TP point-of-care test (POCT) in diagnosing treponemal infection (syphilis or yaws) in patients attending a large HIV clinic in Ghana; to determine the prevalence of treponemal co-infections; and to characterise demographic and clinical features of patients with infection. "

04/01/1951 - "MINIMUM penicillin therapy in the treatment of treponemal infections by WHO/UNICEF field teams."

03/01/1997 - "Acceptability and compliance with daily injections of procaine penicillin in the outpatient treatment of syphilis-treponemal infection."