Tremor (Tremors)

4058  relevant articles (356 outcomes, 294 trials/studies) found for this Disease

Tremors; Intention Tremor; Rest Tremor; Saturnine Tremor; Tremor, Muscle; Tremor, Action; Coarse Tremor; Continuous Tremor; Darkness Tremor; Fine Tremor; Intermittent Tremor; Involuntary Quiver; Massive Tremor; Passive Tremor; Persistent Tremor; Pill Rolling Tremor; Senile Tremor; Static Tremor; Tremor, Limb; Tremor, Neonatal; Tremor, Nerve; Tremor, Perioral; Tremor, Semirhythmic; Action Tremors; Coarse Tremors; Continuous Tremors; Darkness Tremors; Fine Tremors; Intention Tremors; Intermittent Tremors; Involuntary Quivers; Limb Tremor; Limb Tremors; Massive Tremors; Muscle Tremor; Muscle Tremors; Neonatal Tremor; Neonatal Tremors; Nerve Tremor; Nerve Tremors; Passive Tremors; Perioral Tremor; Perioral Tremors; Persistent Tremors; Pill Rolling Tremors; Quiver, Involuntary; Quivers, Involuntary; Rest Tremors; Resting Tremors; Rolling Tremor, Pill; Rolling Tremors, Pill; Saturnine Tremors; Semirhythmic Tremor; Semirhythmic Tremors; Senile Tremors; Static Tremors; Tremor, Coarse; Tremor, Continuous; Tremor, Darkness; Tremor, Fine; Tremor, Intention; Tremor, Intermittent; Tremor, Massive; Tremor, Passive; Tremor, Persistent; Tremor, Pill Rolling; Tremor, Rest; Tremor, Resting; Tremor, Saturnine; Tremor, Senile; Tremor, Static; Tremors, Action; Tremors, Coarse; Tremors, Continuous; Tremors, Darkness; Tremors, Fine; Tremors, Intention; Tremors, Intermittent; Tremors, Limb; Tremors, Massive; Tremors, Muscle; Tremors, Neonatal; Tremors, Nerve; Tremors, Passive; Tremors, Perioral; Tremors, Persistent; Tremors, Pill Rolling; Tremors, Rest; Tremors, Resting; Tremors, Saturnine; Tremors, Semirhythmic; Tremors, Senile; Tremors, Static; Action Tremor; Resting Tremor

Relationship Network

Disease Context: Research Results

Related Diseases

1.	Parkinson Disease (Parkinson's Disease)
2.	Hypokinesia (Bradykinesia)
3.	Dyskinesias (Dyskinesia)
4.	Essential Tremor (Essential Tremors)
5.	Parkinsonian Disorders (Parkinsonism)

Experts

1.	Bain, Peter G: 6 articles (07/2007 - 02/2003)
2.	Tariq, Mohammad: 4 articles (05/2005 - 06/2002)
3.	Arshaduddin, Mohammed: 4 articles (05/2005 - 06/2002)
4.	Grill, Warren M: 3 articles (03/2008 - 06/2007)
5.	Salamone, John D: 3 articles (01/2008 - 12/2004)
6.	Poewe, Werner: 3 articles (01/2008 - 08/2004)
7.	Deuschl, G: 3 articles (08/2007 - 01/2001)
8.	Aziz, Tipu Z: 3 articles (07/2007 - 01/2004)
9.	Beuter, Anne: 3 articles (11/2006 - 11/2003)
10.	Martin, Fredricka C: 3 articles (10/2006 - 06/2004)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Tremor:

1.	Levodopa (L Dopa)FDA LinkGeneric 03/01/2007 - "In both cases, levodopa dramatically improved the tremor" 08/01/1999 - "Two patients had resting and postural tremor, which showed a marked improvement with treatment with levodopa" 04/01/1983 - "In untreated or levodopa-treated patients, there was considerable improvement of akinesia, rigidity, and tremor; on-off symptoms also improved in the levodopa-treated patients" 10/01/1995 - "This study shows that the net postural tremor exhibited by PD patients is improved by levodopa, that levodopa does not augment tremor in the 8- to 12-Hz range, and that this effect is independent of the patient's motor response pattern of oral levodopa." 03/15/2007 - "In humans, such lesions lead to specific motor abnormalities (i.e., akinesia, rigidity, and tremor) that are greatly improved by levodopa treatment" Order ALL the reference details at left...
2.	Propranolol (Inderal)FDA LinkGeneric 01/01/1976 - "Propranolol was most effective in older patients and in those with slow tremor frequencies." 11/01/1975 - "An improvement in tremor was observed in all patients who received propranolol and was most pronounced in the upper extremities" 11/01/2008 - "RESULTS: ZNS was found to be more effective in the treatment of patients with isolated head tremor than propranolol" 12/01/1992 - "The results suggest that the efficacy of sustained propranolol on isolated or prominent essential head tremor is less predictable and satisfactory than expected on the basis of the single-dose response, as compared with hand tremor." 05/01/1990 - "However, following 3-6 months of sustained treatment a proportion of patients required an increase in daily dosage of propranolol in order to maintain adequate symptomatic control of tremor, indicating a relative decrease in tremorolytic efficacy of the drug possibly due to long-term tolerance." Order ALL the reference details at left...
3.	Botulinum Toxins (Botulinum Toxin)IBA 08/01/1996 - "Needle-EMG recordings showed rhythmic, synchronous agonist/antagonist activity in both the splenius capitis and sternocleidomastoideus muscles at a frequency of 2-3 Hz. After administration of botulinum toxin A (DysportR), the tremor markedly improved and vanished completely after a booster" 07/01/2006 - "Isolated high-frequency jaw tremor relieved by botulinum toxin injections." 12/01/1998 - "Botulinum toxin produced a significant functional improvement in tremor (about 20%)" 05/01/2006 - "Botulinum toxin injections are effective in some tremor patterns, especially wrist flexion/extension and head tremor" 07/01/2006 - "This would suggest that botulinum toxin is a safe and effective first line treatment for palatal tremor." Order ALL the reference details at left...
4.	Clonazepam (Rivotril)FDA LinkGeneric 01/01/1996 - "He was then treated with gradually increasing doses of clonazepam; when he received 8 mg/day of clonazepam, his tremor showed marked improvement" 10/31/2007 - "Patients with fast tremor improved on clonazepam" 02/01/2002 - "CONCLUSION: Clonazepam is the first-line treatment for orthostatic tremor" 01/01/1998 - "Clonazepam was used in an open study in 11 MS patients to evaluate the sensitivity of TREMOR, compared to the clinical observations" 10/01/2007 - "Following treatment with clonazepam, the tremors subsided, but were not completely controlled." Order ALL the reference details at left...
5.	LithiumIBA 04/01/2001 - "Although the mean tremor activity subsided toward the end of treatment, tremor activity on the whole was still significantly greater after 6 weeks of combined lithium and antidepressant treatment than at the start of combination therapy" 07/01/1981 - "Patients on lithium had a significantly lower peak frequency of tremor than control subjects (P less than 0.05) and significantly greater extrapyramidal symptoms (P less than 0.01), indicating that tremor appearing after chronic lithium therapy is likely to be an extrapyramidal symptom" 07/01/1995 - "RESULTS: Studies show a wide range of incidence of lithium tremor--4% to 65%--due to differences in defining and reporting this side effect" 01/01/1975 - "Frequency and amplitude of lithium-induced tremor till the ninth day of drug administration are discussed - and constitute only one aspect of a bigger, still going on, study." 01/01/1975 - "Studies of lithium-induced tremor by means of different measurement methods]" Order ALL the reference details at left...
6.	Clozapine (Clozaril)FDA LinkGeneric 12/01/1997 - "A significant reduction of both resting (p < 0.05) and postural (p < 0.05) tremors was observed under clozapine from the first week of treatment through the entire period of the study" 05/01/1999 - "A significant reduction of tremor was reported with chronic clozapine treatment (p <0.01) with no tolerance to drug antitremor effect, whereas sedation markedly decreased after 6-7 weeks of therapy" 10/01/2000 - "Clozapine is an atypical neuroleptic agent, not on the market in Japan, and has been reported to decrease or ameliorate parkinsonian tremor through the studies of open label and double blind crossover as a new drug for parkinsonian tremor." 04/01/1994 - "Under these frequent blood monitoring conditions, in this study Clozapine produced a substantial alleviation of parkinsonian tremor in 17 of 23 patients (73%)" 01/01/1990 - "After preliminary observations on 5 psychotic and 7 nonpsychotic parkinsonian patients had shown unexpected impressive beneficial effects of the atypical neuroleptic clozapine on tremor, an open clinical study including 12 patients was started" Order ALL the reference details at left...
7.	gabapentin (Neurontin)FDA LinkGeneric 07/01/2006 - "The findings confirm that gabapentin is an effective treatment for OT, reducing both tremor and postural instability and improving quality of life, and support its use as add-on or first-line therapy for OT." 09/01/1998 - "Effective treatment of orthostatic tremor with gabapentin." 02/15/2003 - "PATIENTS AND METHODS: We evaluated the efficacy of gabapentin added to basal tremor treatment by means of a 16 month non randomized open study conducted at our Unit on treated and monitored patients" 02/01/2003 - "DATA SOURCES: A search of biomedical literature was completed through MEDLINE and EMBASE (1993-May 2002) to identify all clinical trials pertaining to the use of gabapentin for the treatment of tremor in humans" 07/01/2006 - "Patients were then studied 7 days after drug withdrawal and again after two 2-week periods of treatment with either gabapentin or placebo, using force platform posturography to quantify postural sway and tremor" Order ALL the reference details at left...
8.	Primidone (Sertan)FDA LinkGeneric 01/01/1991 - "The tremor had not been helped by beta-blockers or primidone" 05/21/2007 - "Medical treatment with primidone or beta-blockers effectively controls ET tremor, but in many cases no treatment is needed at all" 05/01/2006 - "Mild to moderate tremor usually will respond to oral agents such as noncardiac selective beta-blockers or primidone" 01/01/2006 - "These results suggest that heterozygosis CYP2C19*1/CYP2C19*2 is associated with the risk for ET, but not with the age at onset of ET, the presentation of acute side effects of primidone, or the existence of head, voice, tongue or chin tremor." 01/01/2006 - "The mean age at onset of ET did not differ significantly between patients with genotypes CYP2C19*1/CYP2C19*2andCYP2C19*1/CYP2C19*1. The frequencies of the genotype CYP2C19*1/CYP2C19*2 and the allelic variant CYP2C19*2 were similar in ET patients who developed acute adverse effects to primidone, in those who tolerated primidone and in controls; the frequencies were also similar in patients with head, voice, tongue and chin tremor compared with controls" Order ALL the reference details at left...
9.	Bromocriptine (Parlodel)FDA LinkGeneric 12/01/1977 - "Both CB 154 and combined therapy (CB 154+Madopar) induced a significant improvement in total disability score, tremor, rigidity, akinesia, self-sufficiency, and some motor performance tests (dynamic tests)" 06/01/1976 - "There was a 26 percent overall improvement with bromocriptine; rigidity, tremor, and facial expression showed the greatest response" 05/01/1976 - "A single administration of bromocriptine resulted in a dose-dependent relief of tremor in monkeys" 05/01/1976 - "The antiparkinsonian activity of bromocriptine, a presumed dopaminergic receptor agonist, was investigated in monkeys with surgically induced tremor and in a group of parkinsonian patients" 01/01/1982 - "When the dose of bromocriptine reached 30 mg daily, after 4 weeks' treatment, a highly significant improvement (p less than 0.001) was observed in the following six variables: bradykinesia, rigidity, tremor, feeding, dressing and speech" Order ALL the reference details at left...
10.	pramipexol (pramipexole)FDA LinkGeneric 05/01/2000 - "In another study pramipexole has been shown to be significantly superior to placebo with an improvement in tremor score by 48% (vs. 13% in the placebo group)" 09/01/1999 - "The patients were drawn from a larger placebo-controlled, double-blind, randomized trial, which was not originally designed to investigate the effect of pramipexole on tremor" 01/01/2006 - "The main reasons for switching to pramipexole (anti-tremor effect, anti-depressive/anti-anhedonic effect) as given by the physicians at baseline came up to expectations" 05/01/2005 - "Patients with pronounced resting tremor derived a clear benefit from pramipexole treatment compared with placebo" 10/01/2003 - "Three weeks after initiation of pramipexol, the tremor artefact was no longer visible on ECG" Order ALL the reference details at left...

Therapies and Procedures

1.	Deep Brain Stimulation 06/28/2005 - "Chronic deep brain stimulation (DBS) (Level C) and thalamotomy (Level C) are highly efficacious in reducing tremor" 03/01/2001 - "CONCLUSION: Excellent to marked improvement of tremor is achieved in the majority of patients with physiological target determination via implanted leads in thalamic deep brain stimulation" 09/01/2008 - "CONCLUSION: This case demonstrates that medically resistant Holmes' tremor related to a thalamic lesion can be successfully treated with thalamic deep brain stimulation." 01/01/2000 - "Deep brain stimulation (DBS) of either target possesses high therapeutic efficacy against tremor in PD" 01/01/1998 - "Long-term treatment by means of bilateral deep-brain stimulation (DBS) in the same 12 patients led to a significant reduction of tremor as well as other cardinal features of PD" Order ALL the reference details at left...
2.	Activities of Daily Living (ADL) 10/01/2003 - "The reduction in tremor scores and improvement in activities of daily living were highly significant compared with baseline and with the stimulation turned off" 08/01/2002 - "Motor functioning, especially tremor, motor complications, depression, and activities of daily living improved highly significantly (P < 0.0005), including self-rating by the patients" 10/01/2005 - "Activities of daily living and tremor significantly improved" 08/01/2004 - "RESULTS: Both subjective and objective measures showed that stimulation was associated with significant improvement at nearly every postoperative interval as compared to pre-operative and stimulation 'off' ratings of activities of daily living functioning, midline tremor, contralateral upper extremity tremor, and contralateral lower extremity tremor" 07/01/2000 - "Overall, patient global assessments (p <0.05), observed tremor scores (p <0.005), water pouring scores (p <0.05), and activities of daily living scores (p <0.005) significantly improved" Order ALL the reference details at left...
3.	Pallidotomy 01/01/2000 - "We here report that although all the motor signs were significantly improved 6 months after pallidotomy, the temporal sequence of tremor response was different from those of other symptoms." 06/01/2000 - "CONCLUSIONS: Contemporary combination of pallidotomy and thalamotomy is effective and safe in treating regular parkinsonian symptoms and intractable tremor." 08/01/1994 - "Ventroposterior pallidotomy has been shown to improve not only rigidity and tremor, but also akinesia" 11/01/1997 - "Based on anatomic studies, surgical misadventures, and empirical observations, there was an abrupt shift regarding the favored target to treat parkinsonian tremor to the thalamus, and most neurosurgeons abandoned pallidotomy in the 1960s" 04/01/1997 - "The goals of this study were to analyze the effect of pallidotomy on parkinsonian tremor and to ascertain whether an association exists between microrecording findings and tremor outcome" Order ALL the reference details at left...
4.	Electrodes (Electrode) 01/01/2007 - "RESULTS: In the patient with MS tremor, we implanted bilateral ventralis intermedius (V.im.) and ventralis oralis anterior (V.o.a.) thalamic electrodes; this patient had significant tremor improvement with stimulation of either V.im" 04/01/2005 - "A second rationalization was that the placement of a second electrode may affect somatotopy, and may, therefore, be beneficial for the treatment of more difficult to control tremor subtypes" 04/01/2006 - "Previously, we reported the use of two DBS electrodes (one at the VIM/VOP border and one at the VOA/VOP border) as effective for the treatment of posttraumatic tremor in a single patient" 02/01/2003 - "We studied the efficacy of DBS at 2 years and 6-7 years after electrode implantations in the ventrointermediate nucleus of the thalamus in 39 patients (20 PD, 19 ET) with severe tremor" 04/01/2002 - "The primary outcome measures were reduction in tremor severity and improvement in tests of hand function when the DBS electrode was turned on, 12 months after surgery" Order ALL the reference details at left...
5.	Aftercare (After-Treatment) 04/01/1988 - "Accelerometer readings showed a significant reduction in amplitude of postural tremor after treatment" 09/01/2008 - "Four months after treatment, the patient developed Holmes' tremor in her left upper extremity" 10/01/2006 - "Scores of tremor before and after treatment and adverse effects were investigated" 10/01/2006 - "Several days after treatment, amplitude of resting tremor ameliorated mildly" 09/01/2000 - "Two patients reported increased "off" time and tremor that reversed after treatment was stopped" Order ALL the reference details at left...