Homologous Transplantation (Allograft)

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12423 relevant articles (495 outcomes, 941 trials/studies) found for this Therapy

Description: Transplantation between individuals of the same species. Usually refers to genetically disparate individuals in contradistinction to isogeneic transplantation for genetically identical individuals.

Also Known As:

Allograft; Homograft; Transplantation, Homologous; Allogeneic Transplantation; Allogeneic Transplantations; Allografts; Homografts; Homologous Transplantations; Transplantations, Allogeneic; Transplantations, Homologous; Transplantation, Allogeneic

Relationship Network

Therapy Context: Research Results

Operative Surgical Procedures: 4

Transplantation: 36585

Homologous Transplantation: 12423

Isogeneic Transplantation: 385

Experts

1.	Durlik, M: 12 articles (11/2007 - 09/2000)
2.	Robbins, Robert C: 10 articles (11/2005 - 02/2002)
3.	Haberal, M: 8 articles (01/2008 - 11/2003)
4.	Lemström, Karl B: 8 articles (04/2007 - 02/2002)
5.	Koskinen, Petri K: 8 articles (04/2007 - 02/2002)
6.	Nicholson, M L: 8 articles (01/2005 - 03/2000)
7.	Haverich, A: 7 articles (09/2008 - 02/2000)
8.	Ozdemir, F N: 7 articles (05/2007 - 11/2003)
9.	Lautenschlager, Irmeli: 7 articles (11/2006 - 11/2002)
10.	Pratschke, J: 7 articles (09/2006 - 08/2000)

Related Diseases

1.	Infection 01/01/2008 - "Transplantation of allogeneic organs has proven to be an effective therapeutic for a large variety of disease states, but the chronic immunosuppression that is required for organ allograft survival increases the risk for infection and neoplasia and has direct organ toxicity" 02/01/1993 - "CONCLUSIONS: Although complete protection against persistent or recurrent infection has not been achieved and late deterioration may be expected, in situ allograft replacement seems to be a major advance in the management of infected infrarenal aortic prosthetic grafts." 08/01/1985 - "These data suggest that a significant reduction in morbidity and possibly mortality could be accomplished by complete eradication of infection prior to allograft nephrectomy" 03/01/2007 - "CONCLUSIONS: Prophylaxis is beneficial in preventing direct and indirect effects of CMV infection in transplant recipients, affecting both allograft and patient survival" 07/15/2005 - "CONCLUSIONS: The use of sterile allograft tissue appears to be associated with a significant reduction in the risk of postoperative infection, particularly in the presence of adjunctive fixation" Get all the results and reference details, order at left...
2.	Neoplasms (Cancer) 08/27/2003 - "The best treatment-withdrawal or reduction of immunosuppression-permits tumor rejection but risks allograft rejection" 05/28/1996 - "While systemic tumor control was improved by systematic chemotherapy, local tumor control was improved by appropriate biopsy techniques, and amputations have been replaced by local resections, in most cases with reconstruction (arthrodesis, rotation plasty, endoprosthesis, allografts), which require further improvements" 01/01/2006 - "In allografts of naïve ES BRCA1-/- cells there was either partial or complete remission of tumors" 08/01/2008 - "Allograft is a commonly used technique to reconstruct a large osseous defect following tumor excision in the United States and some European countries, and relatively good results have been reported because of its biologic nature" 10/01/2005 - "However, based on our data and the good outcome for more extensive and destructive tumors, allograft implants can be used for treatment of patients with aggressive tumors, tumors that have caused fractures, or tumors that have recurred after conservative treatment." Get all the results and reference details, order at left...
3.	Reperfusion Injury 04/01/1999 - "RESULTS: After 1 hour of reperfusion, gas exchange function (p < 0.01), tissue lipid peroxide levels (p < 0.05) and histologic damage in reperfused lung allografts (p< 0.05) were significantly improved in lazaroid-treated group IV compared with control group I. CONCLUSIONS: These findings suggest that lazaroid U74389G ameliorates ischemia-reperfusion injury in rat lung transplants by inhibiting lipid peroxidation." 09/01/1997 - "In the swine model the decrease flow from baseline in allograft post-reperfusion renal blood flow was significantly greater in kidneys preserved in Collins'-2 than in University of Wisconsin solution (41.75 +/- 5.69 versus 11.18 +/- 13.99 ml. per minute, p = 0.005), supporting that this technique can assess mild to moderate reperfusion injury" 03/27/2000 - "CONCLUSIONS: Hyperbaric pressure is a safe and effective vector for the ex vivo delivery of AS-ICAM-1-ODN to rodent cardiac allografts and results in a reduction in reperfusion injury." 07/01/1999 - "In view of these protective effects and its low toxicity in humans, GSH should be considered a candidate drug for prevention of ROS-related reperfusion injury of the liver allograft." 06/15/2003 - "Short-term immunosuppressive treatment of the donor ameliorates consequences of ischemia/ reperfusion injury and long-term graft function in renal allografts from older donors." Get all the results and reference details, order at left...
4.	Autoimmune Diseases (Autoimmune Disease) 01/01/2006 - "FTY is highly effective in prolonging allograft survival in preclinical models of transplantation and in experimental models of autoimmune diseases" 01/01/2005 - "Immunosuppressive drugs have improved the therapeutic management of allograft organ transplantation and autoimmune diseases, significantly" 10/01/1993 - "The introduction of CsA in the early 1970's significantly improved the outcome of organ and bone marrow allograft transplantation and advanced therapeutic options in autoimmune diseases" 07/27/2001 - "CONCLUSIONS: If mixed chimerism can be achieved safely with novel low-intensity conditioning regimens and results in sustained remission of autoimmune diseases, allogeneic transplantation may become a realistic therapy in the management of some patients with autoimmune disease." 10/01/1990 - "Inter-T cell TCR-ABCMC may be particularly effective in inflammatory tissues, such as rejecting allografts and autoimmune diseases, in which numerous cytolytic T lymphocytes are present in close association with other T cells." Get all the results and reference details, order at left...
5.	Leukemia 02/01/1995 - "Whereas immunomagnetic CD34+ selection is most effective in terms of elimination of T cells, the less intensive T and NK cell depletions achieved with CAMPATH-1 might be advantageous with regard to retaining engraftment potential and graft-vs.-leukemia (GVL) activity of PBPC allografts." 10/01/1988 - "Allogeneic transplantation versus intensive chemotherapy in first-remission acute leukemia: is there a "best choice"?" 11/01/2001 - "Allogeneic transplantation has been demonstrated to be effective with a strong suggestion of graph versus leukemia effect" 07/01/1999 - "We conclude that patients with acute leukemia who are alive and well without chronic GVHD two years following an allograft have a high probability of being cured, whereas patients with active chronic GVHD requiring immunosuppression continue to be at risk of non-relapse death" 04/15/1997 - "Allogeneic transplantation with CD6 depleted bone marrow is effective in consolidating remissions of high-risk patients with acute leukemia in first remission without excessive toxicity." Get all the results and reference details, order at left...
1189 Diseases and 12423 more articles analyzed in the Research Interface, order at left...

Related Drugs and Biologics

1.	Cyclosporine (Ciclosporin)
2.	Monoclonal Antibodies
3.	Lamivudine (3TC)
4.	Sirolimus (Rapamycin)
5.	mycophenolate mofetil (Cellcept)
6.	fludarabine
7.	Intercellular Adhesion Molecule-1 (Intercellular Adhesion Molecule 1)
8.	Antigens
9.	Tacrolimus (Prograf)
10.	Melphalan (Alkeran)
1086 Drugs and Important Bio-Agents and 3217 more articles analyzed in the Research Interface, order at left...

Related Therapies and Procedures

1.	Transplants (Transplant)
2.	Transplantation (Transplant Recipients)
3.	Homologous Transplantation (Allograft)
4.	Autologous Transplantation (Autograft)
5.	Kidney Transplantation
193 Therapies and Procedures and 4583 more articles analyzed in the Research Interface, order at left...

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