|1.||Jakobs, Cornelis: 7 articles (01/2014 - 04/2004)|
|2.||Salomons, Gajja S: 6 articles (12/2014 - 04/2004)|
|3.||Perl, Andras: 6 articles (07/2011 - 01/2004)|
|4.||Wamelink, Mirjam M C: 5 articles (12/2014 - 01/2011)|
|5.||Niland, Brian: 5 articles (04/2010 - 01/2004)|
|6.||Banki, Katalin: 4 articles (04/2010 - 09/2004)|
|7.||Verhoeven, Nanda M: 3 articles (11/2006 - 04/2004)|
|8.||Jakobs, C: 3 articles (01/2005 - 05/2001)|
|9.||Verhoeven, N M: 3 articles (01/2005 - 05/2001)|
|10.||van der Knaap, M S: 3 articles (01/2005 - 05/2001)|
12/15/2005 - "Transaldolase (TAL) is expressed at selectively high levels in oligodendrocytes and targeted by autoreactive T cells of patients with multiple sclerosis (MS). "
01/01/2004 - "Transaldolase is a target of autoimmunity mediated by T cells and antibody (Ab) in patients with multiple sclerosis. "
01/01/2004 - "Evaluation of autoimmunity to transaldolase in multiple sclerosis."
10/01/1999 - "Molecular mimicry between immunodominant autoepitopes and viral Ags may be a decisive factor in directing autoimmunity to transaldolase in multiple sclerosis patients."
03/15/1997 - "Comparative analysis of antibody and cell-mediated autoimmunity to transaldolase and myelin basic protein in patients with multiple sclerosis."
01/01/2011 - "Novel heterozygous mutations in TALDO1 gene causing transaldolase deficiency and early infantile liver failure."
06/01/2009 - "Recent case reports suggest a link between the pentose phosphate pathway (PPP) enzyme transaldolase (TAL; encoded by TALDO1) and liver failure in children. "
01/01/2005 - "Discovery of this second patient affected with transaldolase deficiency and liver failure suggests that this disorder has a heterogeneous clinical presentation with highly variable severity."
06/01/2004 - "A deficiency of transaldolase was found in the patient presenting with liver failure. "
01/01/2005 - "A newborn with severe liver failure, cardiomyopathy and transaldolase deficiency."
01/01/2011 - "Transaldolase deficiency has been diagnosed in 11 patients from 6 families in which the probands presented in the newborn and antenatal period with hepatospIenomegaly, hemolytic anaemia, hepatic fibrosis, kidney problems. "
06/01/2008 - "Transaldolase deficiency in a two-year-old boy with cirrhosis."
01/01/2014 - "After failing to identify a diagnosis after routine metabolic evaluation, we utilized a combination of RNA-Seq and whole exome sequencing to identify a novel homozygous p.Ser171Phe Transaldolase (TALDO1) variant in the proband, his brother with cirrhosis, as well as a clinically asymptomatic older 8-year-old brother. "
05/01/2015 - "Transaldolase deficiency is a heterogeneous disorder of carbohydrate metabolism characterized clinically by dysmorphic features, cutis laxa, hepatosplenomegaly, hepatic fibrosis, pancytopenia, renal and cardiac abnormalities, and urinary excretion of polyols. "
11/01/2006 - "Transaldolase (TALDO) deficiency is a newly recognized metabolic disease, which has been reported so far in 2 patients presenting with liver failure and cirrhosis. "
01/01/2013 - "During carbon starvation, the ribose-derived carbon accumulates as sedoheptulose-7-phosphate, whose consumption by transaldolase is impaired due to depletion of transaldolase's other substrate, glyceraldehyde-3-phosphate. "
01/01/1992 - "Starvation of rats for 24 hr resulted in a 1.6- to 3.1-fold increase in liver and kidney glucose 6-phosphatase and phosphoenolpyruvate carboxykinase (P less than or equal to 0.05), a decrease in liver and kidney FDP (P less than 0.002), and an increase in liver and kidney transaldolase (P = 0.0001). "
11/01/2013 - "Despite N starvation-induced dramatic remodeling of the transcriptome, there were relatively few differences (5 × 10(2)) observed between sta6 and STA6, the most dramatic of which were increased abundance of transcripts encoding key regulated or rate-limiting steps in central carbon metabolism, specifically isocitrate lyase, malate synthase, transaldolase, fructose bisphosphatase and phosphoenolpyruvate carboxykinase (encoded by ICL1, MAS1, TAL1, FBP1, and PCK1 respectively), suggestive of increased carbon movement toward hexose-phosphate in sta6 by upregulation of the glyoxylate pathway and gluconeogenesis. "
|5.||Liver Cirrhosis (Hepatic Cirrhosis)
05/01/2001 - "Transaldolase deficiency: liver cirrhosis associated with a new inborn error in the pentose phosphate pathway."
09/01/2004 - "Homozygous deletion of three nucleotides coding for Ser-171 (S171) of TAL-H (human transaldolase) has been identified in a female patient with liver cirrhosis. "
04/01/2004 - "Recently, we described a patient with liver cirrhosis and abnormal polyol levels in body fluids, related to a deficiency of transaldolase, another enzyme in the PPP. "
|5.||Glucosephosphate Dehydrogenase (Glucose 6 Phosphate Dehydrogenase)
|10.||Interleukin-1alpha (Interleukin 1 alpha)