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Congenital Toxoplasmosis

Prenatal protozoal infection with TOXOPLASMA gondii which is associated with injury to the developing fetal nervous system. The severity of this condition is related to the stage of pregnancy during which the infection occurs; first trimester infections are associated with a greater degree of neurologic dysfunction. Clinical features include HYDROCEPHALUS; MICROCEPHALY; deafness; cerebral calcifications; SEIZURES; and psychomotor retardation. Signs of a systemic infection may also be present at birth, including fever, rash, and hepatosplenomegaly. (From Adams et al., Principles of Neurology, 6th ed, p735)
Also Known As:
Toxoplasmosis, Congenital; Congenital Infection, Toxoplasma gondii; Congenital Toxoplasma Infections; Toxoplasma Infections, Congenital; Congenital Toxoplasma Infection; Congenital Toxoplasmoses; Fetal Toxoplasmoses; Fetal Toxoplasmosis; Infection, Congenital Toxoplasma; Infections, Congenital Toxoplasma; Prenatal Toxoplasmoses; Prenatal Toxoplasmosis; Toxoplasma Infection, Congenital; Toxoplasmoses, Congenital; Toxoplasmoses, Fetal; Toxoplasmoses, Prenatal; Congenital Toxoplasma gondii Infection; Toxoplasmosis, Fetal; Toxoplasmosis, Prenatal
Networked: 313 relevant articles (13 outcomes, 32 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Hearing Loss (Hearing Impairment)
2. Bacterial Meningitis
3. Communicable Diseases (Infectious Diseases)
4. Infection
5. Toxoplasmosis

Experts

1. Petersen, Eskild: 11 articles (06/2011 - 11/2002)
2. Wallon, Martine: 8 articles (04/2015 - 06/2004)
3. McLeod, Rima: 8 articles (07/2014 - 03/2006)
4. Peyron, François: 7 articles (04/2015 - 06/2004)
5. Buffolano, Wilma: 5 articles (06/2011 - 12/2005)
6. Petersen, E: 5 articles (08/2006 - 01/2000)
7. Boyer, Kenneth: 4 articles (12/2011 - 03/2006)
8. Gargano, Nicola: 4 articles (06/2011 - 12/2005)
9. Gilbert, Ruth E: 4 articles (08/2009 - 01/2007)
10. Schmidt, Dorte Remmer: 4 articles (01/2006 - 06/2003)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Congenital Toxoplasmosis:
1. Immunoglobulin M (IgM)IBA
2. Pyrimethamine (Daraprim)FDA Link
3. AntibodiesIBA
4. Immunoglobulin G (IgG)IBA
5. Immunoglobulin A (IgA)IBA
6. SpiramycinIBA
7. AntigensIBA
8. Sulfadiazine (Sulphadiazine)FDA Link
9. DNA (Deoxyribonucleic Acid)IBA
10. SulfonamidesIBA

Therapies and Procedures

1. Drug Therapy (Chemotherapy)
2. Prenatal Care
3. Intravitreal Injections
4. Fetal Therapies (Fetal Therapy)
5. Highly Active Antiretroviral Therapy (HAART)