|1.||Hearing Loss (Hearing Impairment)
|3.||Communicable Diseases (Infectious Diseases)
|1.||Petersen, Eskild: 11 articles (06/2011 - 11/2002)|
|2.||Wallon, Martine: 8 articles (04/2015 - 06/2004)|
|3.||McLeod, Rima: 8 articles (07/2014 - 03/2006)|
|4.||Peyron, François: 7 articles (04/2015 - 06/2004)|
|5.||Buffolano, Wilma: 5 articles (06/2011 - 12/2005)|
|6.||Petersen, E: 5 articles (08/2006 - 01/2000)|
|7.||Boyer, Kenneth: 4 articles (12/2011 - 03/2006)|
|8.||Gargano, Nicola: 4 articles (06/2011 - 12/2005)|
|9.||Gilbert, Ruth E: 4 articles (08/2009 - 01/2007)|
|10.||Schmidt, Dorte Remmer: 4 articles (01/2006 - 06/2003)|
|1.||Immunoglobulin M (IgM)IBA
09/01/2010 - "This study showed that the WB assay is a useful tool to confirm a diagnosis of congenital toxoplasmosis and that the IgM-WB-positive results can indicate active macular lesions in newborn infants."
08/01/2009 - "PCR test targeting P30 gene was positive in 13 with additional four fetuses, only PCR gave positive results, and serologic follow-up of suspected fetuses (17) by IgM ELISA confirmed congenital toxoplasmosis. "
11/01/2007 - "The first aim of this study was to determine the prevalence of congenital toxoplasmosis in newborn infants treated by the public health system in Porto Alegre, a city in southern Brazil, using neonatal screening for Toxoplasma gondii-specific IgM. "
06/01/1994 - "Seroprevalence studies of congenital toxoplasmosis can be based on IgM measurement by ISAGA using eluates of filter paper stored infants' blood. "
01/01/1992 - "In this study, the combination of fast detection methods, ie cell culture and PCR of amniotic fluid, eosinophil and platelet counts, GGT activity and specific IgM, enabled us to confirm 10/10 cases of congenital toxoplasmosis in less than a week. "
|2.||Pyrimethamine (Daraprim)FDA Link
11/10/1968 - "[Hypsarrhythmic syndrome caused by congenital toxoplasmosis cured with pyrimethamine]."
01/01/2011 - "The study objective was to determine plasma concentration of pyrimethamine in 24 infants aged 1-5 months, treated for congenital toxoplasmosis. "
09/01/2014 - "Pyrimethamine (PYR) is a drug used in the treatment of newborn with congenital Toxoplasmosis. "
10/01/2011 - "We report the case of a newborn child affected by asymptomatic congenital toxoplasmosis who received an overdose of pyrimethamine. "
10/01/2011 - "Curative treatment of congenital toxoplasmosis is based on the association of pyrimethamine and sulfonamide. "
04/01/2009 - "The purpose of this study was to investigate the antibodies to Toxoplasma gondii in human immunodeficiency virus (HIV)-infected pregnant women and to determine the association between serological profile and the risk of congenital toxoplasmosis. "
09/01/1999 - "The aim of this study was to retrospectively evaluate the performance of a Western blot assay to compare mother and newborn anti-Toxoplasma gondii antibodies for the early neonatal diagnosis of congenital toxoplasmosis. "
11/01/2012 - "In a retrospective study, serum Toxoplasma gondii antibodies were measured in samples from 333 infants, including 212 noninfected infants and 121 infants with congenital toxoplasmosis. "
11/01/2012 - "Testing of toxoplasma-specific antibodies in infants identifies congenital toxoplasmosis during the first year of life. "
10/01/2010 - "To investigate the serological diagnosis of congenital toxoplasmosis and the prevalence of antibodies against toxoplasma in pregnant women in our area. "
|4.||Immunoglobulin G (IgG)IBA
01/01/2013 - "The aim of this study was to evaluate the association between clinical signs of congenital toxoplasmosis and IgG subclasses found in newborns participating in the Minas Gerais State Neonatal Screening Program. "
09/01/2006 - "This study investigated the prevalence of specific Toxoplasma gondii IgG in pregnancy, the incidence of congenital toxoplasmosis and the prevalence trend of T. "
04/01/2015 - "Use of IgG in oral fluid to monitor infants with suspected congenital toxoplasmosis."
05/01/2014 - "Under serological monitoring of newborns, 21 cases were lost to follow-up and monitoring was stopped for 29 after decrease of anti-toxoplasmic IgG. The prenatal diagnosis allowed to decrease the severe forms of congenital toxoplasmosis in Tunisia. "
06/01/2013 - "Evaluation of IgG anti-toxoplasma avidity and polymerase chain reaction in the postnatal diagnosis of congenital toxoplasmosis."
|5.||Immunoglobulin A (IgA)IBA
08/01/1977 - "The use of IgA subclass IgA1 and IgA2 was not helpful in distinguishing infants with congenital toxoplasmosis from unaffected infants. "
04/01/2015 - "A retrospective analysis of 145 medical records from our teaching hospital laboratory showed an overall specificity of greater than 97% for the IgA immunosorbent agglutination assay (ISAGA A) performed on the sera of babies to diagnose congenital toxoplasmosis (CT). "
04/01/2015 - "Assessment of the IgA immunosorbent agglutination assay for the diagnosis of congenital toxoplasmosis on a series of 145 toxoplasmic seroconversions."
01/01/1999 - "Lack of value of specific IgA detection in the postnatal diagnosis of congenital toxoplasmosis."
08/01/1995 - "IMx Toxo IgA must not be used to diagnose congenital toxoplasmosis."
08/01/2004 - "Treatment with spiramycin was effective in preventing congenital toxoplasmosis in children of sero-positive mothers who consented to treatment."
05/01/1998 - "Congenital toxoplasmosis: efficacy of maternal treatment with spiramycin alone."
01/01/2014 - "The purpose of this study was to assess methods for the confirmation of congenital toxoplasmosis after maternal treatment with spiramycin during pregnancy, and to evaluate the effect of this treatment on clinical manifestations of the disease in newborns (NB). "
01/01/2014 - "Assessment of laboratory methods used in the diagnosis of congenital toxoplasmosis after maternal treatment with spiramycin in pregnancy."
11/01/1996 - "[Prevention of congenital toxoplasmosis with spiramycin; value and limits of levels in amniotic fluid]."
12/01/2005 - "gondii-infected from uninfected infants and shows that assays based on recombinant antigens improve the diagnosis of newborns with congenital toxoplasmosis."
12/01/2005 - "Use of recombinant antigens for early postnatal diagnosis of congenital toxoplasmosis."
02/01/2005 - "gondii RH strain tachyzoite antigen and validated the method with sera from 11 children identified through the neonatal screening program for congenital toxoplasmosis in Denmark. "
05/01/1999 - "Protective immunity in the rat model of congenital toxoplasmosis and the potential of excreted-secreted antigens as vaccine components."
01/01/1992 - "White blood cells in infants with congenital toxoplasmosis: transient appearance of cALL antigen on reactive marrow lymphocytes."
|8.||Sulfadiazine (Sulphadiazine)FDA Link
05/01/1949 - "Experimental toxoplasmosis; effect of sulfadiazine and antiserum on congenital toxoplasmosis in mice."
01/01/1995 - "The efficacy of the combination of pyrimethamine and sulfadiazine for the treatment of congenital Toxoplasma gondii infection in rhesus monkeys was studied. "
04/01/2012 - "Protocols recommended in the USA and Germany for the postnatal treatment of congenital toxoplasmosis are mainly based on the National Collaborative Chicago-based Congenital Toxoplasmosis Study that calls for daily administration of pyrimethamine in combination with sulfadiazine for several months, then 3 times a week. "
01/01/2006 - "The aim was to study the tolerability and plasma concentrations of pyrimethamine and sulfadiazine in children treated for congenital toxoplasmosis. "
01/01/1995 - "Study of treatment of congenital Toxoplasma gondii infection in rhesus monkeys with pyrimethamine and sulfadiazine."
|9.||DNA (Deoxyribonucleic Acid)IBA
12/01/2009 - "However, our results showed that the DNA extraction procedures led to variable efficacy in isolating low concentrations of tachyzoites in AF samples (<5 Toxoplasma gondii cells/ml), a difference that might have repercussions since low parasite concentrations in AF exist and can lead to congenital toxoplasmosis."
01/01/2003 - "Detection of TOX-DNA in amniotic fluid with FQ-PCR technique can diagnose fetal toxoplasmosis exactly. "
01/01/1998 - "A case of congenital toxoplasmosis is presented, where diagnosis by PCR amplification of Toxoplasma gondii DNA from peripheral blood led to early treatment of the infant and seemingly normal brain development despite the presence of intracranial calcifications at birth. "
05/01/1996 - "[The clinical implications of Toxoplasma gondii specific DNA detected by quantitative competitive polymerase chain reaction in treated patient with congenital toxoplasmosis]."
01/01/2001 - "The introduction of Polymerase Chain Reaction (PCR) assay for detection of Toxoplasma gondii DNA in selected cases of pathologic pregnancies has permitted a more accurate and faster diagnosis of congenital toxoplasmosis infections."
11/01/1989 - "Efficacy of the additional treatment with pyrimethamine and sulfonamides was demonstrated by a significant reduction of severe congenital toxoplasmosis and the relative decrease of the ratio of benign to subclinical forms. "
05/01/1998 - "The evidence supporting an additional benefit of a combined regimen of pyrimethamine-sulfonamides compared with spiramycin alone in the secondary prevention of congenital toxoplasmosis was critically evaluated. "
|1.||Drug Therapy (Chemotherapy)
09/01/1991 - "A rat model of congenital toxoplasmosis is described for the study of protective immunity and chemotherapy during pregnancy. "
11/01/2014 - "Herein, we describe a case report in which symptomatic congenital toxoplasmosis was avoided in a pregnant woman with an immunosuppressive risk due to prompt chemotherapy."
01/01/1995 - "The second part suggests a practical approach to the problem of congenital toxoplasma infection, including diagnostic work-up, drug therapy, and follow-up. "
09/30/1990 - "Chemotherapy of the infected pregnant mother reduces the incidence of congenital toxoplasmosis and the severity of the disease in the newborn. "
01/01/2014 - "Congenital toxoplasmosis and prenatal care state programs."
11/01/2007 - "Maternal serology at delivery and neonatal screening were especially useful in the identification of infants with congenital toxoplasmosis when the mother did not receive regular prenatal serological testing or prenatal care."
11/01/2007 - "Although four mothers of the patients with congenital toxoplasmosis received prenatal care, and three mothers had one or two serological tests for T. "
|4.||Fetal Therapies (Fetal Therapy)
|5.||Highly Active Antiretroviral Therapy (HAART)