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Tosylphenylalanyl Chloromethyl Ketone (TPCK)

An inhibitor of Serine Endopeptidases. Acts as alkylating agent and is known to interfere with the translation process.
Also Known As:
TPCK; Chloromethane, Tosylphenylalanyl; Chloromethyl Ketone, Tosylphenylalanyl; Ketone, Tosylphenylalanyl Chloromethyl; Chlorophenyltosylamidobutanone; Tosylphenylalanyl Chloromethane; Benzenesulfonamide, N-(3-chloro-2-oxo-1-(phenylmethyl)propyl)-4-methyl-, (S)-
Networked: 46 relevant articles (0 outcomes, 2 trials/studies)

Bio-Agent Context: Research Results

Experts

1. LeBlanc, Michael H: 3 articles (12/2006 - 11/2002)
2. Feng, Yangzheng: 3 articles (12/2006 - 11/2002)
3. Guo, Jun: 2 articles (03/2010 - 12/2009)
4. Ignatius, Myron S: 1 article (06/2013)
5. Poss, Kenneth D: 1 article (06/2013)
6. Pugach, Emily K: 1 article (06/2013)
7. Chen, Eleanor Y: 1 article (06/2013)
8. Zon, Leonard I: 1 article (06/2013)
9. Wills, Airon A: 1 article (06/2013)
10. Hettmer, Simone: 1 article (06/2013)

Related Diseases

1. Brain Injuries (Brain Injury)
2. Carcinoma (Carcinomatosis)
3. Neoplasms (Cancer)
4. Infection
5. Necrosis

Related Drugs and Biologics

1. Caspase 3 (Caspase-3)
2. wortmannin
3. Tosyllysine Chloromethyl Ketone
4. NF-kappa B (NF-kB)
5. Protease Inhibitors (Protease Inhibitor)
6. Phenylalanine (L-Phenylalanine)
7. Serine Proteases (Serine Protease)
8. Serine Proteinase Inhibitors (Serine Protease Inhibitors)
9. Etoposide (VP 16)
10. Chymotrypsin

Related Therapies and Procedures

1. Aftercare (After-Treatment)
2. Drug Therapy (Chemotherapy)