|2.||Onychomycosis (Tinea Unguium)
|1.||Yamaguchi, Hideyo: 7 articles (06/2012 - 01/2002)|
|2.||Fleischer, Alan B: 5 articles (10/2015 - 11/2011)|
|3.||Gupta, Aditya K: 5 articles (01/2015 - 09/2003)|
|4.||Tortoriello, Jaime: 5 articles (01/2013 - 05/2003)|
|5.||Herrera-Arellano, Armando: 5 articles (01/2013 - 05/2003)|
|6.||Watanabe, Shinichi: 5 articles (04/2009 - 01/2003)|
|7.||Tanuma, H: 5 articles (04/2004 - 01/2000)|
|8.||Yamaguchi, H: 5 articles (06/2001 - 01/2000)|
|9.||Verma, Amit: 4 articles (10/2015 - 08/2013)|
|10.||Olayinka, Babajide: 4 articles (10/2015 - 08/2013)|
|1.||terbinafine (Lamisil)FDA LinkGeneric
09/01/2001 - "In most cases, one week of therapy with topical terbinafine is effective for interdigital tinea pedis. "
10/01/1990 - "We conclude that terbinafine is well tolerated and highly effective in moccasin-type tinea pedis."
01/01/2008 - "To study and establish an optimal administration method of oral antifungal, terbinafine (TBF), for hyperkeratotic type tinea pedis, from the pharmacokinetic point of view, 20 patients with hyperkeratotic type tinea pedis were given TBF 125 mg once daily for 4 weeks and observed over time for improvement in dermatological symptoms and mycological efficacy. "
01/01/2007 - "Terbinafine is very well tolerated in any topical pharmaceutical formulation and also has high efficacy as a cure for tinea pedis, irrespective of type of pharmaceutical formulation, treatment duration, and frequency of application, including the recently established one-shot regimen. "
01/01/2008 - "Thus, we conclude that the high efficacy of short-term treatment with terbinafine in patients with tinea pedis is possible due to its fungicidal activity coupled with a distinct reservoir formation in the upper layers of the epidermis."
|2.||Itraconazole (Sporanox)FDA LinkGeneric
09/01/2005 - "The present study demonstrated that the efficacy of the original and generic itraconazole is not significantly different in the treatment of tinea pedis by the pulse regimen."
01/01/1998 - "Short-term treatment with itraconazole was significantly more effective than placebo in tinea pedis. "
09/01/2005 - "To study the efficacy of the 1-pulse dosing regimen of two generic products of itraconazole (Itracon and Itra) in comparison with the innovative product (Sporal) for the treatment of tinea pedis. "
04/01/2004 - "In the present study, the authors administered 100 mg itraconazole (ITCZ) twice daily for a period of 1 week to six patients with hyperkeratotic type tinea pedis, and examined its efficacy, safety profile, and usefulness. "
01/01/2002 - "Thirty-four patients (17 men and 17 women) with intractable tinea pedis, with informed consent, took 200 mg of itraconazole once daily for one week over a month period until mycological studies showed negative results for up to 4 months. "
|3.||Clotrimazole (Lotrimin)FDA LinkGeneric
01/01/1977 - "Clotrimazole proved to be effective in the treatment of tinea pedis of both the interdigital and the plantar hyperkeratotic types."
05/01/1979 - "Investigation of clotrimazole usage in tinea pedis without nail involvement."
01/01/1977 - "Topical clotrimazole in tinea pedis."
02/08/2002 - "The Food and Drug Administration (FDA) is issuing a final rule amending the final monograph for over-the-counter (OTC) topical antifungal drug products to add the ingredient clotrimazole as generally recognized as safe and effective for the treatment of athlete's foot, jock itch, and ringworm. "
09/01/2014 - "A synthetic, azole antimycotic, clotrimazole is widely used as a topical treatment for tinea pedis (athlete's foot), as well as vulvovaginal and oropharyngeal candidiasis. "
|4.||butenafine (Mentax)FDA Link
02/01/1997 - "Butenafine applied twice daily for 1 week is highly effective in treating interdigital tinea pedis."
02/01/1997 - "We evaluated the safety and efficacy of twice-daily butenafine versus its vehicle in the treatment of interdigital tinea pedis in a multicenter, randomized, double-blind, parallel-group trial. "
02/01/1997 - "One-week therapy with twice-daily butenafine 1% cream versus vehicle in the treatment of tinea pedis: a multicenter, double-blind trial."
02/01/1997 - "We evaluated butenafine in the treatment of tinea pedis in a controlled, randomized, double-blind trial. "
03/01/2000 - "If incorporated properly in semisolid topical preparations, with a balanced vehicle, butenafine hydrochloride potentially exhibits as a promising alternative antimycotic agent for the treatment of tinea pedis."
|5.||Miconazole (Monistat)FDA LinkGeneric
01/01/1982 - "2% Miconazole nitrate powder in aerosol spray form: its efficacy in treating tinea pedis."
08/26/1978 - "Efficacy of topical miconazole treatment of tinea pedis."
07/01/1975 - "Efficacy of miconazole in the topical treatment of tinea pedis in sportsmen."
09/01/1996 - "The results of this study provide indirect evidence that the regular use of miconazole spray powder decreases the risk of developing athlete's foot."
09/01/1996 - "Biometrological assessment of the preventive effect of a miconazole spray powder on athlete's foot."
|6.||Griseofulvin (Grifulvin V)FDA LinkGeneric
01/01/1966 - "Improved griseofulvin therapy for tinea pedis."
02/01/1961 - "A study of griseofulvin as related to tinea pedis."
01/01/2001 - "Treatment for hyperkeratotic type tinea pedis is mainly with oral antimycotics, such as griseofulvin, and healing is generally considered to be difficult with only topical antimycotics. "
06/01/1981 - "A comparison of Gris-PEG and Fulvicin-U/F in the treatment of tinea pedis."
08/01/1978 - "Treatment of "tinea pedis" with griseofulvin and topical antifungal cream."
02/01/2010 - "These findings indicate that sertaconazole nitrate cream 2% is highly safe and effective in the treatment of tinea pedis interdigitalis."
10/01/2006 - "To determine the safety and efficacy of topical sertaconazole nitrate cream 2% in the treatment of tinea pedis, 2 randomized, multicenter, double-blinded, parallel group, vehicle-controlled studies were conducted. "
02/01/2010 - "Safety and efficacy of sertaconazole nitrate cream 2% in the treatment of tinea pedis interdigitalis: a subgroup analysis."
10/01/2006 - "The safety and efficacy of sertaconazole nitrate cream 2% for tinea pedis."
10/01/2011 - "Treatment of interdigital tinea pedis: once-daily therapy with sertaconazole nitrate."
|8.||ciclopirox (Loprox)FDA LinkGeneric
09/01/2003 - "Ciclopirox, a broad-spectrum hydroxypyridone antifungal, has proven efficacy against the organisms commonly implicated in tinea pedis; Trichophyton rubrum, T.mentagrophytes and Epidermophyton floccosum. "
09/01/2003 - "Ciclopirox gel 0.77% applied twice daily for 4 weeks is an effective treatment of moderate interdigital tinea pedis due to T. "
09/01/2003 - "Two multicenter, double-blind, clinical studies compared the efficacy and safety of ciclopirox gel with that of its vehicle base in subjects with moderate interdigital tinea pedis with or without plantar involvement. "
09/01/2003 - "Ciclopirox gel in the treatment of patients with interdigital tinea pedis."
05/01/1989 - "Ciclopirox olamine lotion 1% was found to be significantly more effective than its vehicle in the treatment of patients with common tinea pedis. "
|9.||Ketoconazole (Nizoral)FDA LinkGeneric
10/01/2002 - "In the present study, the efficacy of Oleozon in the treatment of tinea pedis was demonstrated in a controlled randomized phase III assay, comparing topical Oleozon with ketoconazole cream 2% (Nizoral) in 200 patients (100 in each group). "
07/01/1987 - "Comparative trial of a two-dosage schedule of ketoconazole 2% cream for the treatment of tinea pedis."
01/01/2015 - "mentagrophytes on fungal culture and clinical response to ketoconazole cream, we conclude that this represents a unique variant of tinea pedis. "
11/01/2006 - "pichinchensis with ketoconazole in patients with the clinical and mycological diagnosis of tinea pedis, we carried out a double-blind pilot study. "
11/01/2006 - "Effectiveness and tolerability of a standardized extract from Ageratina pichinchensis on patients with tinea pedis: an explorative pilot study controlled with ketoconazole."
|10.||Fluconazole (Zonal)FDA LinkGeneric
03/01/1998 - "Efficacy of oral fluconazole in tinea pedis of the hyperkeratotic type. "
11/01/1992 - "Seventy adult out-patients with tinea pedis participated in a multicentre open non-comparative study of the safety and efficacy of once-weekly doses of oral fluconazole 150 mg. A mean of 3 doses of fluconazole was administered; patients infected with Candida required an average of 2 doses compared to 3-4 doses in patients infected with other organisms. "
03/01/1998 - "In this study, in addition to studying the efficacy and safety of the once-daily administration of 100-mg capsules of fluconazole over an 8-week administration period with six patients with hyperkeratotic-type tinea pedis, we also measured the serum and horny layer concentrations of fluconazole to study the mobility into the horny layer in diseased areas of the sole skin. "
11/01/1992 - "Once-weekly oral doses of fluconazole 150 mg in the treatment of tinea pedis."
08/01/1996 - "This study demonstrated that weekly oral doses of fluconazole 150mg were effective in the treatment of tinea corporis, tinea cruris, tinea pedis and cutaneous candidosis. "
05/01/2013 - "Undetected tinea pedis in a patient with diabetes can lead to serious bacterial infections with potentially serious consequences, such as foot amputations. "
06/01/2006 - "Significant predictors (P </= 0.05) of foot ulcer in the final model (hazard ratio, 95% CI) included A1C (1.10, 1.06-1.15), impaired vision (1.48, 1.00-2.18), prior foot ulcer (2.18, 1.61-2.95), prior amputation (2.57, 1.60-4.12), monofilament insensitivity (2.03, 1.50-2.76), tinea pedis (0.73, 0.54-0.98), and onychomycosis (1.58, 1.16-2.16). "
01/01/2011 - "Effective treatment of tinea pedis and onychomycosis is crucial for patients with diabetes as these infections may lead to foot ulcers and secondary bacterial infections resulting in eventual lower limb amputation. "
06/01/2006 - "At baseline we assessed age; race; weight; current smoking; diabetes duration and treatment; HbA(1c) (A1C); visual acuity; history of laser photocoagulation treatment, foot ulcer, and amputation; foot shape; claudication; foot insensitivity to the 10-g monofilament; foot callus; pedal edema; hallux limitus; tinea pedis; and onychomycosis. "
01/01/2002 - "Relapse of the disease was observed in 4 of 51 patients at 1 year after treatment, 4 of 25 at 2 years, and 2 of 9 at 3 years in the plantar type, and in 4 of 30 at 1 year, 0 of 14 at 2 years, and 0 of 6 at 3 years in the interdigital tinea pedis group. "
01/01/2000 - "Tinea pedis and onychomycosis cleared after treatment with topical antifungals with or without systemic antifungals in all cases. "
01/01/1994 - "An 11-year-old boy presented with inflamed tinea pedis followed by a generalized id type skin eruption, with disappearance of the rash after treatment of the mycotic foot lesions. "
|4.||Traditional Medicine (Folk Remedies)
10/01/1994 - "[A study on effectiveness of treatment and prevention of relapse using topical administration of terbinafine in a guinea pig model for tinea pedis]."
07/01/2000 - "The clinical efficacy and safety of once daily topical administration of 1% oxiconazole cream and lotion was assessed in an open label, non comparative trial in tinea cruris, tinea corporis and tinea pedis patients. "