Thyrotropin (Thyroid-Stimulating Hormone)

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3799 relevant articles (78 outcomes, 244 trials/studies) found for this Drug

Description: A glycoprotein hormone secreted by the adenohypophysis (PITUITARY GLAND, ANTERIOR). Thyrotropin stimulates THYROID GLAND by increasing the iodide transport, synthesis and release of thyroid hormones (THYROXINE and TRIIODOTHYRONINE). Thyrotropin consists of two noncovalently linked subunits, alpha and beta. Within a species, the alpha subunit is common in the pituitary glycoprotein hormones (TSH; LUTEINIZING HORMONE and FSH), but the beta subunit is unique and confers its biological specificity.

Also Known As:

Thyroid-Stimulating Hormone; Thyreotropin; Thyrotrophin; Hormone, Thyroid-Stimulating; TSH (Thyroid Stimulating Hormone); Thyroid Stimulating Hormone

Relationship Network

Drug Context: Research Results

Hormones, Hormone Substitutes, and Hormone Antagonists

Hormones: 46163

Peptide Hormones: 377

Pituitary Hormones: 369

Anterior Pituitary Hormones: 108

Thyrotropin: 3799

alpha Subunit Glycoprotein Hormones: 166

beta Subunit Thyrotropin: 111

exophthalmos producing substance: 10

human chorionic thyrotropin protein: 2

dansyl thyrotropin

deglycosylated thyrotropin

recombinant hTSHbeta.CTPalpha protein

thyrotropin-alpha-lactalbumin-daunomycin conjugate

thyrotropin-daunomycin conjugate

Amino Acids, Peptides, and Proteins

Peptides: 16335

Peptide Hormones: 377

Pituitary Hormones: 369

Anterior Pituitary Hormones: 108

Thyrotropin: 3799

alpha Subunit Glycoprotein Hormones: 166

beta Subunit Thyrotropin: 111

exophthalmos producing substance: 10

human chorionic thyrotropin protein: 2

dansyl thyrotropin

deglycosylated thyrotropin

recombinant hTSHbeta.CTPalpha protein

thyrotropin-alpha-lactalbumin-daunomycin conjugate

thyrotropin-daunomycin conjugate

Experts

1.	Hegedüs, Laszlo: 7 articles (10/2008 - 12/2003)
2.	Braverman, Lewis E: 6 articles (11/2007 - 07/2002)
3.	Robbins, Richard J: 5 articles (11/2006 - 07/2002)
4.	Beck-Peccoz, P: 5 articles (04/2001 - 04/2000)
5.	Bonnema, Steen J: 4 articles (10/2008 - 12/2003)
6.	Grupe, Peter: 4 articles (10/2008 - 07/2006)
7.	Boel-Jørgensen, Henrik: 4 articles (10/2008 - 01/2005)
8.	Pacini, Furio: 4 articles (09/2007 - 09/2002)
9.	Nielsen, Viveque Egsgaard: 4 articles (11/2006 - 01/2005)
10.	Reiners, Christoph: 4 articles (03/2006 - 10/2003)

Related Diseases

1.	Hypothyroidism 07/01/2006 - "Bovine thyrotropin (bTSH) stimulation testing has long been considered the gold standard for diagnosis of canine hypothyroidism. " 01/01/2002 - "RESULTS: In three of the patients, l-T4 administration could be discontinued and the clinical symptoms of hypothyroidism disappeared because of an improved serum thyroid-stimulating hormone level. " 04/01/1999 - "The gold standard for diagnosis of hypothyroidism remains the thyroid-stimulating hormone response test. " 03/01/1979 - "An improved double antibody radioimmunoassay for measuring human thyrotropin (h-TSH) in serum, suitable for neonatal primary hypothyroidism screening is described. " 12/01/1976 - "A method for measuring thyrotropin (TSH) in eluates of dried blood samples on filter paper was evaluated and improved as a screening test for neonatal hypothyroidism. " Order ALL the reference details at left...
2.	Hyperthyroidism 04/01/1988 - "We report a prospective multicenter study, undertaken to compare the efficacy of 10 highly sensitive thyrotropin assay kits for the diagnosis of hyperthyroidism. " 08/01/1997 - "In the remission group, to exclude the influence of subclinical hyperthyroidism, thyrotropin (TSH) levels were followed and subjects with low levels excluded. " 08/01/1984 - "In contrast, there is now a large body of work which shows that thyrotrophin receptor antibody levels, central to the aetiology of Graves' hyperthyroidism, fall during antithyroid treatment and that remission may be related to this fall in a fashion which is dependent on the dose and duration of treatment. " 10/01/2006 - "A study population of 4087 subjects (2050 women) without overt hyperthyroidism or increased serum thyrotropin levels was available for the present study. " 09/01/2005 - "PURPOSE: To evaluate the prevalence of latent and manifest hyperthyroidism in a non-selected group of patients admitted for contrast enhanced CT studies blood samples were tested for the levels of thyroid-stimulating hormone (TSH). " Order ALL the reference details at left...
3.	Neoplasms (Cancer) 07/02/1987 - "Serum levels of thyrotropin were dramatically reduced by treatment in four of the five patients, and levels of another tumor marker, the alpha-subunit of thyrotropin, were reduced in all five. " 06/01/2009 - "The mechanisms responsible for the progression of thyroid tumors toward a thyroid-stimulating hormone (TSH)-independent phenotype are still under discussion, and a better understanding of them may provide novel molecular targets for the treatment of this disease. " 05/01/2009 - "We compared retrospectively Group I and Group II in terms of volume of residual thyroid tissue, thyroid stimulating hormone (TSH) values, complication rates and incidence of tumor found in the residual thyroid. " 03/01/2009 - "During thyrotropin stimulation the tumor enlarged. " 02/01/2009 - "RESULTS: Low thyrotropin levels (<0.50 mU/L) were associated with increased cancer risk [adjusted hazard ratio (HR), 1.34; 95% confidence interval (CI), 1.06-1.69] compared with the euthyroid reference group. " Order ALL the reference details at left...
4.	Graves Disease (Basedow Disease) 01/01/1991 - "A follow-up study of 85 patients with Graves' disease in remission who developed undetectable serum thyroid-stimulating hormone concentrations using sensitive TSH assays." 01/30/1988 - "[Ultrasensitive determination of thyrotropin in Graves' disease in remission]" 08/01/1984 - "An improved assay for thyrotropin-binding blocking activity in serum of patients with Graves' disease." 12/01/2003 - "We compared T cell responses in wild-type and B cell-deficient mice immunized with the thyrotrophin receptor (TSHR), the major autoantigen in Graves' disease. " 12/01/2003 - "Thyrotrophin receptor-specific memory T cell responses require normal B cells in a murine model of Graves' disease." Order ALL the reference details at left...
5.	Pituitary Neoplasms (Pituitary Adenoma) 11/01/1990 - "Thyrotropin-secreting pituitary adenomas have been diagnosed more frequently as radiographic techniques and biochemical assays have improved; however, they remain uncommon and are unfamiliar to most neurosurgeons. " 08/01/2004 - "Pathological study of thyrotropin-secreting pituitary adenoma: plurihormonality and medical treatment." 06/01/1989 - "Clinical and molecular studies of a thyrotropin-secreting pituitary adenoma." 01/01/2009 - "[Thyrotropin-secreting pituitary adenomas]" 12/01/2008 - "Thyrotropin-secreting pituitary adenomas: biological and molecular features, diagnosis and therapy." Order ALL the reference details at left...

Related Drugs and Biologics

1.	Thyroxine (Levothyroxine)
2.	Octreotide (Sandostatin)
3.	Hormones
4.	Adrenocorticotropic Hormone (ACTH)
5.	Triiodothyronine (Liothyronine)
6.	Antibodies
7.	Prolactin
8.	Immunoglobulins (Immunoglobulin)
9.	Somatostatin (Somatotropin Release-Inhibiting Factor)
10.	Thyrotropin (Thyroid-Stimulating Hormone)

Related Therapies and Procedures

1.	Aftercare (After-Treatment)
2.	Thyroidectomy
3.	Drug Therapy (Chemotherapy)
4.	Hormone Replacement Therapy (Therapy, Hormone Replacement)
5.	Renal Dialysis (Hemodialysis)

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