Thyroiditis

Subscribe to Selected New Research on Thyroiditis

2095 relevant articles (39 outcomes, 164 trials/studies) found for this Disease

Description: Inflammatory diseases of the THYROID GLAND. Thyroiditis can be classified into acute (THYROIDITIS, SUPPURATIVE), subacute (granulomatous and lymphocytic), chronic fibrous (Riedel's), chronic lymphocytic (HASHIMOTO DISEASE), transient (POSTPARTUM THYROIDITIS), and other AUTOIMMUNE THYROIDITIS subtypes.

Also Known As:

Thyroiditides

Relationship Network

Disease Context: Research Results

Endocrine System Diseases: 398

Thyroid Diseases: 3109

Thyroiditis: 2095

Autoimmune Thyroiditis: 1086

Subacute Thyroiditis: 315

Suppurative Thyroiditis: 20

Related Diseases

1.	Graves Disease (Basedow Disease)
2.	Thyrotoxicosis
3.	Hyperthyroidism
4.	Hypothyroidism
5.	Thyroid Diseases (Thyroid Disease)

Experts

1.	Amino, Nobuyuki: 6 articles (02/2007 - 12/2002)
2.	Miyauchi, Akira: 4 articles (02/2007 - 07/2004)
3.	Segni, Maria: 4 articles (08/2004 - 06/2002)
4.	Badenhoop, Klaus: 4 articles (08/2004 - 06/2002)
5.	Usadel, Klaus-H: 4 articles (08/2004 - 06/2002)
6.	Takano, Kazue: 3 articles (05/2008 - 02/2005)
7.	Ito, Koichi: 3 articles (12/2007 - 01/2004)
8.	Fukata, Shuji: 3 articles (02/2007 - 02/2005)
9.	Ito, Mitsuru: 3 articles (02/2007 - 07/2004)
10.	Matsuzuka, Fumio: 3 articles (02/2007 - 12/2002)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Thyroiditis:

1.	AntibodiesIBA 01/01/1994 - "False positive results obtained in 4 hypothyroid patients with Hashimoto's thyroiditis (serum TSH concentrations, 11-171 mU/L) could be prevented using anti-TSH antibodies. " 03/01/2006 - "The study group included 26 BC patients with thyroperoxidase antibodies positivity (TPOAb+), 14 of them (53.8%) with Hashimoto's thyroiditis (HT), and 30 BC patients with no evidence of thyroid autoimmune disorders. " 10/20/1979 - "The present study demonstrates that the serum of one patient with Hashimoto's thyroiditis contained antibodies which 1) blocked the binding of lablled TSH to the receptor, 2) had no thyroid-stimulating activity by themselves, and 3) inhibited AC stimulation by TSH. " 11/01/1976 - "Thyroid antibodies in the sera of BUF rats are closely correlated with spontaneous thyroiditis; their detection may facilitate the study of this animal model of organ-specific autoimmunity. " 12/20/1967 - "[Clinical studies on chronic thyroiditis with reference to thyroid antibodies in the blood]" Order ALL the reference details at left...
2.	IodineIBA 01/01/2008 - "Pathological studies made in different regions indicate that these types of thyroiditis occur more frequently in areas of iodine sufficiency than in areas of iodine deficiency, and increase after iodine prophylaxis both in non-goitrous and iodine-deficient areas like Salta, Argentina. " 11/01/1993 - "Previous studies have shown that dietary iodine enhances the severity and incidence of focal thyroiditis in autoimmune BB rats and OS chickens. " 12/20/1970 - "1. Studies on relationship between histological picture and iodine metabolism in chronic thyroiditis]" 11/01/1968 - "Studies on iodine metabolism in chronic thyroiditis." 05/01/1965 - "STUDIES OF IODINE METABOLISM IN HASHIMOTO'S THYROIDITIS." Order ALL the reference details at left...
3.	Thyroxine (Levothyroxine)FDA LinkGeneric 01/01/2000 - "In a novel departure, the NMR outbred strain has been treated by genetic immunisation with very promising results, including the induction of increased thyroxine levels in 4/30 female mice, accompanied by TSAB in addition to thyroiditis, and with signs of hyperactivity and orbital pathology. " 07/01/2008 - "CONCLUSION: Serum TPO-Ab levels decline in most patients with Hashimoto's thyroiditis who are taking levothyroxine, but after a mean of 50 months, TPO-Ab became negative in only a minority of patients." 07/01/2006 - "The objective of this prospective study was to evaluate both thyroid function in children with Hashimoto's thyroiditis and the necessity of lifetime thyroxine replacement therapy. " 06/01/2005 - "Thirty-three patients who had diagnosis of euthyroid Hashimoto's thyroiditis were randomized to two groups, one group received prophylactic L-thyroxine treatment and the other was followed-up without treatment. " 09/01/2003 - "Her past history included thyroiditis treated by L-thyroxin for two years. " Order ALL the reference details at left...
4.	Antithyroid Agents (Antithyroid Drugs)IBA 01/01/2007 - "Patients with thyroiditis or long history of antithyroid drugs for more than one year were excluded from the study. " 09/06/1951 - "Treatment of acute thyroiditis with antithyroid drugs." 01/01/1988 - "The possible immunosuppressive action of antithyroid drugs in vivo has been assessed using Buffalo (Buf) strain rats with thyroiditis produced by neonatal thymectomy; this model shares many features with spontaneous thyroiditis in man. " 09/12/1992 - "Antithyroid drugs, concentrated within thyroid cells, will prevent the release of these inflammatory molecules, which may in turn explain the amelioration of thyroiditis and remission of Graves' disease after such treatment." 11/01/2001 - "This study collected Doppler ultrasonography data from patients with GD, Hashimoto's thyroiditis, and simple goiter to develop a hemodynamic index for use in the evaluation of when antithyroid drugs (ATDs) should be withdrawn or ablative therapy given in GD. " Order ALL the reference details at left...
5.	Thyroglobulin FDA Link 12/01/1984 - "In our studies of patients with Hashimoto's thyroiditis, peripheral lymphocytes of patients produced a significantly greater number of plaques than lymphocytes from normal subjects on challenging with thyroglobulin. " 07/01/1985 - "The induction of tolerance to thyroglobulin significantly reduces the severity of thyroiditis in obese strain chickens." 11/01/1990 - "As we were unable to demonstrate proliferation by blood T cells + LDC from all thyroglobulin antibody-positive patients with Hashimoto's thyroiditis, our studies suggest that the presence of sufficient precursor T cells, as well as the number and type of antigen-presenting cells, are critical for T cell proliferative responses to human TPO and thyroglobulin." 04/01/1987 - "In serial studies of immunopathologic changes in an animal model of thyroiditis 52 rabbits were immunized with either bovine, porcine or human thyroglobulin (Tg) in Freund's complete adjuvant, while another 47 animals served as noninjected or adjuvant injected controls. " 09/01/1983 - "These studies revealed an abnormal elevation in serum thyroglobulin (Tg) concentrations of the thyroiditis-prone OS chicks. " Order ALL the reference details at left...
6.	HormonesIBA 03/01/2006 - "The treatment of the thyroiditis with suppressive doses of thyroid hormone often results in the remission of the CU. " 03/01/1990 - "A study comparing the reproductive histories of 89 women affected by Hashimoto's thyroiditis (HT) with 89 matched controls has been carried out to determine whether endogenous hormones contribute to the development of the disease. " 02/01/1990 - "All patients had severe thyroid hormone deficiency due to chronic thyroiditis and had been receiving no medication at the time of this study. " 12/01/2007 - "Evaluation of thyroid hormone action in a case of generalized resistance to thyroid hormone with chronic thyroiditis: discovery of a novel heterozygous missense mutation (G347A)." 06/01/2007 - "CONCLUSION: The incidental finding of increased (18)F-FDG uptake in the thyroid gland is associated with chronic lymphocytic (Hashimoto's) thyroiditis and does not seem to be affected by thyroid hormone therapy. " Order ALL the reference details at left...
7.	Amiodarone (Amiodarona)FDA LinkGeneric 05/01/2003 - "All patients in both groups became euthyroid and had their amiodarone-induced destructive thyroiditis cured as defined by normalization of both serum free T(4) and free T(3) levels, during both drugs therapy. " 06/29/2002 - "Amiodarone-induced thyroiditis." 06/29/2002 - "Amiodarone-induced thyroiditis." 01/05/2002 - "Clinical picture: amiodarone-induced thyroiditis." 12/01/1998 - "These in vitro findings and clinical course suggest that TRAb/TBII without thyroid-stimulating activity may develop in patients with amiodarone-induced destructive thyroiditis, as reported in patients with destructive thyroiditis, such as subacute and silent thyroiditis." Order ALL the reference details at left...
8.	Hydrocortisone (Cortisol)FDA LinkGeneric 10/01/2001 - "In contrast, cortisol levels were lower in Hashimoto's thyroiditis (13.5 +/- 3.2 microg/dl) vs. normal state (16.0 +/- 1.13 microg/dl), (p < 0.05). " 11/01/1992 - "Therefore, TSH excess before adrenal replacement may be attributed to not only direct enhancement of TSH release due to chronic cortisol deficiency but also to thyroid dysfunction due to chronic thyroiditis. " 02/01/1996 - "Diabetes insipidus gradually improved and hydrocortisone treatment was begun at three months after onset, but a month later painless thyroiditis developed. " 08/01/1996 - "The height of the pituitary gland gradually decreased from 22 mm (14 days after delivery) to 13 mm (73 days) and became rapidly smaller (4.9 mm, 115 days) following administration of massive doses of hydrocortisone for the treatment of acute adrenal insufficiency induced by painless thyroiditis. " 01/01/1982 - "During the course of a year's replacement with hydrocortisone, goiter developed, which, on biopsy, was diagnosed as typical Hashimoto's thyroiditis. " Order ALL the reference details at left...
9.	GlucocorticoidsIBA 10/01/2007 - "Thus, under most circumstances, endocrinologists nowadays deal with type 2 AIT, which is a destructive thyroiditis, generally treated successfully with glucocorticoids. " 10/01/2009 - "CONCLUSIONS: Glucocorticoids are the first-line treatment in type 2 AIT, whereas thionamides play no role in this destructive thyroiditis." 10/01/2007 - "Type 2 AIT is a destructive thyroiditis, responds to glucocorticoids, and usually does not require further thyroid treatment once euthyroidism has been restored. " 05/01/2003 - "Type II AIT, a destructive thyroiditis, often favorably responds to glucocorticoids. " 10/01/1996 - "We have therefore determined sICAM-1 levels by a sandwich enzyme linked immunosorbent assay (ELISA) method in 10 patients with subacute thyroiditis (Group 1), who are at the initial or acute phase of thyroiditis, in 10 hypothyroidic patients with Hashimoto's thyroiditis (Group 2), in 10 patients with euthyroid nodular goiter (Group 3), in 10 patients with untreated GD patients with active ophthalmopathy (Group 4), in 10 hyperthyroid GD patients without clinical ophthalmopathy (Group 5), in 10 patients with GO who are euthyroid and treated with glucocorticoids for 3 months (Group 6) and in 20 normal subjects (Control Group). " Order ALL the reference details at left...
10.	AutoantibodiesIBA 05/01/2001 - "The remaining 36 patients had thyroid autoantibodies (Abs+) at the end of treatment, and they subsequently showed a heterogeneous behavior: 16 patients remained Abs+ for the whole length of the study (persistent thyroiditis); 10 patients became Abs- 6 months off therapy but were again Abs+ 6.2 yr later (remitting/relapsing thyroiditis); 10 patients reverted to autoantibody negativity at different observation times (transient thyroiditis). " 12/01/2007 - "A cohort of 10 Hashimoto's encephalopathy (HE) patients, 33 patients with unrelated neurological symptoms, 12 Hashimoto's thyroiditis patients and 4 healthy adult donors was studied to explore the neurological targets of anti-thyroperoxidase (TPO) autoantibodies (aAb) in HE. " 05/01/2005 - "We investigated autoantibodies and their epitope(s) in Hashimoto's encephalopathy associated with Hashimoto's thyroiditis. " 04/01/2005 - "The proposita, her affected mother as well as her unaffected sister have thyroid autoantibodies consistent with Hashimoto's thyroiditis, and a heterozygous point mutation in exon 10 encoding the ligand (3,3',5-L-T3)-binding domain of the TRbeta gene was detected in both the proposita and the mother. " 07/01/2002 - "RESULTS: Nine female patients (14%) showed anti-thyroid autoantibodies, in particular: TgA in 3 cases, TPOA in 5, TgA and TPOA in only 1. In 3 of these patients, ultrasound examinations showed thyroid abnormal pattern, suggesting Hashimoto's thyroiditis. " Order ALL the reference details at left...

Therapies and Procedures

1.	Thyroidectomy 12/01/1986 - "In a consecutive series of thyroidectomies over a 22-year period, all patients with factors predisposing them to neoplasia, such as a history of radiation exposure and thyroiditis, were eliminated. " 06/01/1998 - "The objective of the present investigation was to study quantitatively C cells in Hashimoto's thyroiditis (HT) by analyzing 22 thyroids obtained at autopsy or thyroidectomy from 16 patients with thyroiditis and from 6 normal subjects. " 06/01/1994 - "Those who underwent total thyroidectomy (n = 14), in whom the histological diagnosis was thyroiditis (n = 10), or who were lost to follow up (n = 31) were excluded from the study. " 06/01/1981 - "The incidence of chronic (Hashimoto's) thyroiditis in surgical specimens is relatively high, i.e., 13% in collected studies, for a disease with clinical and laboratory characteristics that are sufficiently specific, that thyroidectomy should rarely be required for diagnosis or treatment. " 07/01/2008 - "CONCLUSIONS: Thyroidectomy can be performed in patients with Hashimoto's thyroiditis with a low risk of permanent surgical complications. " Order ALL the reference details at left...
2.	Drug Therapy (Chemotherapy) 10/01/1981 - "Tuberculous thyroiditis cured by drug therapy." 01/01/2005 - "There is no evidence that chemotherapy can influence the thyroid function, but radiotherapy can cause thyroiditis with later hypofunction. " 07/01/1987 - "Acute thyroiditis as a complication of chemotherapy administration through a Hickman catheter." 11/01/1999 - "Considering the clinical course in this case, thyroidectomy may be indicated for lymphoproliferative diseases in Hashimoto's thyroiditis treated with chemotherapy." 11/01/1990 - "Studies were conducted in hypothyroid patients, and significant reductions in R-R interval variations were observed in patients with primary severe hypothyroidism due to Hashimoto's thyroiditis, and in patients with Graves' disease who became severely hypothyroid during antithyroid drug therapy. " Order ALL the reference details at left...
3.	Aftercare (After-Treatment) 04/01/2004 - "We have evaluated both assays (TRAb and pCTTRAb) in 300 individuals: healthy controls (n = 51); patients with GD before and after treatment (n = 200), patients with MNG (n = 29), and Hashimoto's thyroiditis [HT; n = 20]). " 11/01/1994 - "Interestingly, the TGPO aAb level significantly decreased in patients with Hashimoto's thyroiditis after hormonal therapy (P < 0.05), some of them shifting from TGPO aAb positive before treatment to negative after treatment. " 01/01/1975 - "The susceptibility to the effect of MC was not expressed in most F-1 hybrids of BUF and Lewis (LEW), a strain of rat that does not develop thyroiditis after treatment with MC." 07/01/1991 - "To investigate the immune regulating effect of moxibustion on the patients with Hashimoto's thyroiditis, 35 patients were treated by moxibustion and the changes of antibody-dependent cell-mediated cytotoxicity (ADCC) activity in the peripheral blood of the patients and their relationship with thyroid microsomal antibody (MCA) before and after treatment were observed. " 04/01/1997 - "Twelve were in remission after treatment for Graves' disease, and 4 had destructive thyroiditis. " Order ALL the reference details at left...
4.	Moxibustion 03/01/1993 - "A study on the clinical effect and immunological mechanism in the treatment of Hashimoto's thyroiditis by moxibustion." 09/01/1987 - "A clinical study of treating Hashimoto's thyroiditis by moxibustion." 03/01/1996 - "Clinical observation on Hashimoto's thyroiditis treated by indirect moxibustion with various Chinese medicines." 03/01/1993 - "The results indicate that the treatment of Hashimoto's thyroiditis by moxibustion is probably accomplished through its effect in regulating the relationship among the T lymphocyte subsets." 03/01/1993 - "71 cases of Hashimoto's thyroiditis were treated by moxibustion and their immune function and thyroid function were observed. " Order ALL the reference details at left...
5.	Heterologous Transplantation (Xenotransplantation) 01/01/1994 - "Human thyroid xenografts from 7 patients with Hashimoto's thyroiditis (HT) and 3 normal persons (N) were xenografted into severe combined immunodeficient (SCID) mice to study the intrathyroidal lymphocytes that were expected to survive in these animals. " 01/01/1993 - "Reconstitution of severe combined immunodeficient mice with intrathyroidal lymphocytes of thyroid xenografts from patients with Hashimoto's thyroiditis." 01/01/1993 - "Thyroid tissues from patients with Hashimoto's thyroiditis (HT) have been xenografted to both severe combined immunodeficiency (SCID) mice and nude mice to study the intrathyroidal lymphocytes which were expected to migrate from the xenografts in the SCID mice. " 01/01/1994 - "Studies of human thyroid xenografts from Hashimoto's thyroiditis in severe combined immunodeficient (SCID) mice: detection of thyroid stimulation-blocking antibody." 12/01/1995 - "After the xenografts had been 8 weeks in nude mice, ICAM-1 expression decreased markedly in AITD TEC [from 56% to 10% in Hashimoto's thyroiditis (P < 0.001) and from 54% to 8% in Graves' disease (P < 0.01)], but did not change significantly in NTG or PN. " Order ALL the reference details at left...

Best Treatments:
Research Summary Report
on Thyroiditis

*WARNING* This specific disease subtype has a relatively small number of significant evidence outcomes. You may proceed to order anyway, or go back to the search field and enter a more general type of the target illness. Once your report has been ordered, however, we can't refund the purchase.

CureHunter Patient-Physician Summary Reports collect in one document all the medications ever reported in the US National Library of Medicine—1949 to the present—to be effective against your target disease. CureHunter research summary reports will vary in length from 25 to 250 pages. Analytic charts allow you and your physicians to see at a glance your medication options—including new, promising, off-label and experimental all rated for clinical efficacy.

Free Updates for 1 Year
All 39 Outcomes
Top 200 Key Drugs and Biologics
Top 50 Key Therapies and Procedures
Detailed History Charts
Full Research Reference Details
Sample PDF Report on Psoriasis >>

Price:

$24.00 & Delivery via PDF download
updates for 1 year

Research Interface

Rapidly retrieve summaries of all the evidence for any disease in seconds. Save hours of search and analysis time. CureHunter is unlike any "search engine" you have ever used. Where standard "search engines" produce lists of links, CureHunter quantifies evidence, extracts it from the literature and calculates a result you can use to immediately facilitate evidence based decision making in Real Clinical Time.

Unlimited Disease, Drug and Therapy Search
2 clicks from Disease to Drug to Evidence
Trial References
All the Positive Outcomes
Detailed Relationship Timeline Charts
Full Article Reference Details
Includes Mobile Interface Subscription
One-click to FDA Products/Patents
Request Institution License Details >>

Price:

$490.00 access via web interface
1 year subscription

Proceed to Checkout >>

Mobile Interface

Retrieve summaries of all the evidence for any disease from your Mobile Phone or PDA. Accelerate decision making in the field. Speed up your study of new drug and disease domains. Refresh your knowledge on the road.

Access from any web enabled PDA or Phone
Trial references
All the Positive Outcomes
Drug and Therapy searches
Full Article Reference Details
Try Mobile Interface >>

Price:

$45.00 access via "curehunter.com/m"
1 year subscription

Proceed to Checkout >>