Thyroid Hormones

01/01/2022 - "Synthetic LT4, titrated to bring the level of TSH within a predefined "normal" reference range, is now established as the mainstay of treatment for hypothyroidism, and provides adequate restoration of thyroid hormone function for most people with this condition. "
05/01/1999 - "Our hypothesis was that those regions that are most dependent on thyroid hormone should present selective increases of D2 as a protection against hypothyroidism. "
11/01/2010 - "If the patient's chronic symptoms are relieved soon after beginning thyroid hormone supplements, it is very likely that the treatment is compensating for hypothyroidism."
03/01/1978 - "In one patient there was good evidence that maternal hypothyroidism improved during the last trimester due to placental transfer of fetal thyroid hormone. "
01/01/2020 - "Hypothyroidism (both subclinical and overt type) is commonly seen in dialysis patients, and its symptoms are ordinary complains even in euthyroid dialysis patients, and this warrants screening programs and more studies on the efficacy of thyroid hormone supplements."

06/10/2003 - "Directly antagonizing the effect of the thyroid hormone at the receptor level may be a significant improvement for the treatment of hyperthyroid patients. "
06/01/1985 - "[Importance of thyroid hormone determination in the diagnosis of hyperthyroidism--significant improvement in medical assessment using decision theory results]."
01/01/1992 - "In order to evaluate how long the exchanges must be continued to be fully effective in extracting thyroid hormones, we evaluated the extraction rate by repeated plasma sampling in two hyperthyroid patients and three euthyroid subjects who underwent a total of seven exchanges. "
09/01/1985 - "Signs of hyperthyroidism may be subtle or misleading, particularly in the elderly; the well-informed clinician keeps the diagnosis in mind, and if the initial thyroid hormone tests are not definitive, employs additional tests that are cost-effective in the individual clinical situation."
01/01/2019 - "The improvement in free thyroid hormones in 70% of subjects receiving the medication suggests potential efficacy as a novel treatment for Graves' hyperthyroidism."

10/29/2016 - "Additionally, the MFS was significantly improved in patients taking thyroid hormone after thyroid cancer surgery. "
06/01/2010 - "We conclude that in patients with cured differentiated thyroid carcinoma, the D2 Thr92Ala polymorphism is associated with a decreased femoral neck BMD and higher bone turnover independent of serum thyroid hormone levels, which points to a potential functional role for D2 in bone."
10/01/2010 - "We evaluated the efficacy of two doses of I-131 (2220 MBq versus 3700 MBq) after thyroid hormone withdrawal for thyroid remnant ablation postoperatively in patients with differentiated thyroid cancer (DTC). "
07/01/2008 - "Thyroid hormone independent associations between serum TSH levels and indicators of bone turnover in cured patients with differentiated thyroid carcinoma."
11/01/2022 - "Further, we have described the role of zebrafish as a model for thyroid cancer, evaluation of defects in thyroid hormone transport, thyroid hormone (TH) metabolism, and as a screening tool to study thyrotoxins. "

01/01/2019 - "Two further subjects had improved free thyroid hormones by the end of the study (7/10 responders), whereas three subjects showed worsening thyrotoxicosis during the study. "
09/01/2013 - "Four months after the diagnosis of thyrotoxicosis, thyroid hormone levels had returned to normal, and native cardiac function had improved remarkably. "
01/01/1993 - "Fecal thyroid hormone measurement may help to provide formal proof of factitious thyrotoxicosis."
01/01/1976 - "However, it was accompanied by an accelerated clearance of the organism from an excess of thyroid hormones; due to this it could not serve as an adequate model of thyrotoxicosis in man."
04/25/2022 - "Our study confirmed the hypothesis of variable kinetics of thyroid hormone levels associated with the manipulation of the thyroid gland during surgery, but none of these changes resulted in clinical effects, including thyrotoxicosis."

08/01/2010 - "PET scans under TSH stimulation versus thyroid hormone suppression showed statistically significant differences in the number of patients with PET true-positive lesions (odds ratio (OR) 2.45, 95% confidence interval (CI) 1.23-4.90) and in the number of the PET-detected lesions (OR 4.92, 95% CI 2.70-8.95) and tumor-to-background ratios. "
01/01/2022 - "These include pleiotropic effects of continuous growth, enhanced thyroid hormone signaling, prevention of neoplasia, and improved memory consolidation. "
07/01/2007 - "Irrespective of the tumor's ability to produce functional thyroid hormone, scintigraphy is often helpful in the diagnosis and staging of thyroid tumors in all three species. "
11/01/1999 - "Spontaneous remission of cancer--a thyroid hormone dependent phenomenon?"
09/11/2023 - "The role of thyroid hormones in cancers has been discussed in observational studies; however, the causal relationship between them remains controversial. "