Thymus Neoplasms (Thymus Neoplasm)

Subscribe to Selected New Research on Thymus Neoplasms

117 relevant articles (6 outcomes, 10 trials/studies) found for this Disease

Description: Tumors or cancer of the THYMUS GLAND.

Also Known As:

Thymus Neoplasm; Tumor, Thymic; Thymus Tumors; Cancer of the Thymus; Neoplasms, Thymic; Neoplasms, Thymus; Thymic Cancer; Thymic Neoplasms; Thymic Tumors; Cancer, Thymic; Cancer, Thymus; Cancers, Thymic; Cancers, Thymus; Neoplasm, Thymic; Neoplasm, Thymus; Thymic Cancers; Thymic Neoplasm; Thymic Tumor; Thymus Cancers; Thymus Tumor; Tumor, Thymus; Tumors, Thymic; Tumors, Thymus; Cancer of Thymus; Thymus Cancer

Relationship Network

Disease Context: Research Results

Neoplasms: 415397

Neoplasms by Site: 1

Thoracic Neoplasms: 17

Thymus Neoplasms: 117

Thymoma: 2248

Hemic and Lymphatic Diseases

Lymphatic Diseases: 1961

Thymus Neoplasms: 117

Thymoma: 2248

Related Diseases

1.	Neoplasms (Cancer)
2.	Thymoma (Thymic Carcinoma)
3.	Lung Neoplasms (Lung Cancer)
4.	Vomiting
5.	Pure Red-Cell Aplasia

Experts

1.	Yasuo, Masanori: 1 article (12/2006)
2.	Fujimoto, Keisaku: 1 article (12/2006)
3.	Yamaguchi, Shinji: 1 article (12/2006)
4.	Urushihata, Kazuhisa: 1 article (12/2006)
5.	Koizumi, Tomonobu: 1 article (12/2006)
6.	Okada, Mitsuyo: 1 article (12/2006)
7.	Kubo, Keishi: 1 article (12/2006)
8.	Hanaoka, Masayuki: 1 article (12/2006)
9.	Tsushima, Kenji: 1 article (12/2006)
10.	Kamiyoshihara, Mitsuhiro: 1 article (11/2005)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Thymus Neoplasms:

1.	Adrenocorticotropic Hormone (ACTH)FDA Link 08/01/1970 - "Ultrastructural studies of an ACTH-secreting thymic tumor." 09/01/1979 - "Addition of rat median eminence extract significantly stimulated ACTH secretion and increased levels of intracellular cAMP in both cell preparations, and a dose-response relationship appeared to exist between the dose of rat median eminence extract added and either ACTH secretion or intracellular cAMP formation in the thymic tumor cells. " 10/01/1976 - "ACTH was purified from thymic tumor associated with ectopic ACTH production by gel filtration and ion exchange chromatography. " 02/01/2008 - "We diagnosed ectopic ACTH-producing tumor, and performed complete excision of the thymus including thymic tumor. " 03/01/1968 - "[Cushing's syndrome caused by a malignant thymus tumor secreting corticotropin]" Order ALL the reference details at left...
2.	Cisplatin (Platino)FDA LinkGeneric 11/01/2005 - "In inoperable locally advanced, or metastatic thymic tumors, neoadjuvant cisplatin-based followed by surgery and radiotherapy has given interesting results in the past years." 01/01/2005 - "Thymic tumors are chemoresponsive with optimal responses achieved with cisplatin-based combination chemotherapy. " 01/01/2008 - "However when thymic cancers are complicated by paraneoplastic syndromes that damage kidney and neurological function, cisplatin use is often contraindicated. " 02/01/2008 - "CONCLUSIONS: Induction therapy for locally advanced thymic tumors with cisplatin, etoposide, and radiation is well tolerated, with many patients having a partial radiographic response. " 06/01/2001 - "BACKGROUND: Patients with thymic tumors (thymoma and thymic carcinoma) are known to respond to a variety of chemotherapeutic agents, including single-agent ifosfamide and cisplatin with etoposide. " Order ALL the reference details at left...
3.	Etoposide (VP 16)FDA LinkGeneric 02/01/2008 - "CONCLUSIONS: Induction therapy for locally advanced thymic tumors with cisplatin, etoposide, and radiation is well tolerated, with many patients having a partial radiographic response. " 11/01/2005 - "[Thymic cancer effectively treated by combination chemotherapy of carboplatin and etoposide with concurrent radiotherapy]" 06/01/2001 - "BACKGROUND: Patients with thymic tumors (thymoma and thymic carcinoma) are known to respond to a variety of chemotherapeutic agents, including single-agent ifosfamide and cisplatin with etoposide. " 10/01/1995 - "A study was conducted to evaluate the impact of cisplatin, doxorubicin, cyclophosphamide and etoposide (PACE) with granulocyte colony-stimulating factor (G-CSF) on advanced thymoma or thymic cancer. " 10/01/1995 - "Intensive chemotherapy with cisplatin, doxorubicin, cyclophosphamide, etoposide and granulocyte colony-stimulating factor for advanced thymoma or thymic cancer: preliminary results." Order ALL the reference details at left...
4.	Doxorubicin (Adriamycin)FDA LinkGeneric 05/01/1998 - "Although no definitive chemotherapy regimen for thymic cancer has yet been established, we feel that the cisplatin, doxorubicin, cyclophosphamide, vincristine 4-drug combination regimen is effective in thymic cancer patients. " 10/01/1995 - "A study was conducted to evaluate the impact of cisplatin, doxorubicin, cyclophosphamide and etoposide (PACE) with granulocyte colony-stimulating factor (G-CSF) on advanced thymoma or thymic cancer. " 10/01/1995 - "Intensive chemotherapy with cisplatin, doxorubicin, cyclophosphamide, etoposide and granulocyte colony-stimulating factor for advanced thymoma or thymic cancer: preliminary results." 10/01/1995 - "Between August 1989 and December 1994, 14 patients with invasive, metastatic or recurrent thymoma or thymic cancer were treated with cisplatin (80 mg/m2, on day 1), doxorubicin (45 mg/m2, on day 1), cyclophosphamide (800 mg/m2, on day 1) and etoposide (80 mg/m2, on day 1-3) with G-CSF (90 micrograms/m2, on day 5-18) at the National Cancer Center Hospital, Tokyo. " Order ALL the reference details at left...
5.	Cyclophosphamide (Cytoxan)FDA LinkGeneric 05/01/1998 - "Although no definitive chemotherapy regimen for thymic cancer has yet been established, we feel that the cisplatin, doxorubicin, cyclophosphamide, vincristine 4-drug combination regimen is effective in thymic cancer patients. " 10/01/1995 - "A study was conducted to evaluate the impact of cisplatin, doxorubicin, cyclophosphamide and etoposide (PACE) with granulocyte colony-stimulating factor (G-CSF) on advanced thymoma or thymic cancer. " 10/01/1995 - "Intensive chemotherapy with cisplatin, doxorubicin, cyclophosphamide, etoposide and granulocyte colony-stimulating factor for advanced thymoma or thymic cancer: preliminary results." 10/01/1995 - "Between August 1989 and December 1994, 14 patients with invasive, metastatic or recurrent thymoma or thymic cancer were treated with cisplatin (80 mg/m2, on day 1), doxorubicin (45 mg/m2, on day 1), cyclophosphamide (800 mg/m2, on day 1) and etoposide (80 mg/m2, on day 1-3) with G-CSF (90 micrograms/m2, on day 5-18) at the National Cancer Center Hospital, Tokyo. " Order ALL the reference details at left...
6.	HormonesIBA 03/01/1990 - "It is suggested that information on the thymic hormone content might add a new parameter to pathological diagnosis in thymic tumors." 01/01/1996 - "To understand the thymic hormone production in thymic tumors and the myasthenic thymus, we have studied the concentrations of two thymic hormones (prothmosin alpha and thymosin beta 4) in these tissues. " 01/15/1994 - "RESULTS: In 25 patients (86%) we found a primary hyperparathyroidism, in 15 patients (52%) an adenoma of the anterior pituitary (seven patients with growth hormone-secreting adenomas, five patients with prolactinomas, two patients with hormone-inactive and one patient with an ACTH-secreting adenoma), in ten patients (34%) a neoplasm of the pancreatic islet cells (six patients with gastrinomas, four patients with insulinomas and two patients with multihormone tumors) and in ten patients (34%) other endocrine tumors (five carcinoid tumors, three adenomas of the adrenal cortex, one papillary thyroid carcinoma and one thymic tumor). " 03/01/1997 - "First, data supporting the "genomic" action via the nuclear sex hormone receptor complexes are as follows: 1) sex hormone receptors and the thymic factor (thymulin) are co-localized in thymic epithelial cells, but not in T cells; 2) production/expression of thymic factors (thymulin, thymosin alpha 1) are remarkably inhibited by sex hormone treatment; 3) sex hormones cause changes in T cell subpopulations in the thymus; and 4) sex hormones strongly influence the development of thymus tumors in spontaneous thymoma BUF/Mna rats through their receptor within the tumor cells. " 09/01/1979 - "In the thymic tumor cells, norepinephrine, serotonin, and TRH were found to be effective in increasing ACTH secretion and intracellular cAMP levels, whereas biogenic amines, hypothalamic hormones, and gastrointestinal hormones did not affect hormone secretion in the thyroid tumor cells. " Order ALL the reference details at left...
7.	Carboplatin (JM8)FDA LinkGeneric 12/01/2006 - "Intrapericardial administration of carboplatin is a useful therapy for control of pericardial effusion and chemosensitive cases should de identified among patients with thymic cancer." 12/01/2006 - "[Successful treatment of intrapericardial administration of carboplatin following systemic chemotherapy in a case of advanced thymic cancer with cardiac tamponade]" 11/01/2005 - "[Thymic cancer effectively treated by combination chemotherapy of carboplatin and etoposide with concurrent radiotherapy]" Order ALL the reference details at left...
8.	Vincristine (Oncovin)FDA LinkGeneric 05/01/1998 - "Although no definitive chemotherapy regimen for thymic cancer has yet been established, we feel that the cisplatin, doxorubicin, cyclophosphamide, vincristine 4-drug combination regimen is effective in thymic cancer patients. " Order ALL the reference details at left...
9.	Serotonin (5 Hydroxytryptamine)IBA 09/01/1979 - "In the thymic tumor cells, norepinephrine, serotonin, and TRH were found to be effective in increasing ACTH secretion and intracellular cAMP levels, whereas biogenic amines, hypothalamic hormones, and gastrointestinal hormones did not affect hormone secretion in the thyroid tumor cells. " Order ALL the reference details at left...
10.	Norepinephrine (Noradrenaline)FDA LinkGeneric 09/01/1979 - "In the thymic tumor cells, norepinephrine, serotonin, and TRH were found to be effective in increasing ACTH secretion and intracellular cAMP levels, whereas biogenic amines, hypothalamic hormones, and gastrointestinal hormones did not affect hormone secretion in the thyroid tumor cells. " Order ALL the reference details at left...

Therapies and Procedures

1.	Drug Therapy (Chemotherapy) 12/01/1999 - "ADOC chemotherapy appears to be an effective treatment for thymic cancer." 06/01/2005 - "CONCLUSIONS: The multimodality treatment of stage III and IVA thymic tumors allows a good long-term outcome; the neoadjuvant chemotherapy improves the resectability rate and the survival of both stages of the disease." 01/01/2005 - "Patients with disseminated (stage IVB) thymic tumors can also have significant disease response and palliation of symptoms when treated with chemotherapy. " 01/01/2005 - "Chemotherapy has an important role in the treatment of advanced thymic tumors. " 01/01/2005 - "Role of chemotherapy in the management of advanced thymic tumors." Order ALL the reference details at left...
2.	Thymectomy 04/01/2002 - "BACKGROUND: The aim of this study is to evaluate the impact of thymectomy in patients with thymic neoplasms and to identify clinical and histopathological factors associated with improved long-term outcome of surgery. " 07/01/2001 - "Thymic neoplasms are also rarely associated, and thymectomy during subtotal or total parathyroidectomy should always be considered. " 09/01/2008 - "A thymic tumor was suspected and the patient had a thymectomy that revealed an atypical carcinoid tumor with pleural carcinosis. " 09/01/2008 - "RESULTS: We enrolled 67 patients with thymoma and 11 with other thymic tumors, all of whom underwent thymectomy. " 09/15/2007 - "Extended thymectomy was applied to MG patients with thymus hyperplasia or thymic tumor. " Order ALL the reference details at left...
3.	Combination Drug Therapy (Combination Chemotherapy) 01/01/2005 - "Thymic tumors are chemoresponsive with optimal responses achieved with cisplatin-based combination chemotherapy. " 11/01/2005 - "[Thymic cancer effectively treated by combination chemotherapy of carboplatin and etoposide with concurrent radiotherapy]" Order ALL the reference details at left...
4.	Intra-Arterial Infusions 11/01/2003 - "These results show that intra-arterial infusion chemotherapy may be effective for local control of advanced thymic cancer." 11/01/2003 - "[A case of advanced thymic cancer successfully treated with neoadjuvant intra-arterial infusion chemotherapy]" Order ALL the reference details at left...
5.	Transplantation (Transplant Recipients) 02/01/1991 - "Further studies of tumor cell isolates demonstrated an increased frequency of colony formation on soft agar, as well as the ability to elicit thymic tumors upon transplantation. " Order ALL the reference details at left...

Best Treatments:
Research Summary Report
on Thymus Neoplasms

*WARNING* This specific disease subtype has a relatively small number of significant evidence outcomes. You may proceed to order anyway, or go back to the search field and enter a more general type of the target illness. Once your report has been ordered, however, we can't refund the purchase.

CureHunter Patient-Physician Summary Reports collect in one document all the medications ever reported in the US National Library of Medicine—1949 to the present—to be effective against your target disease. CureHunter research summary reports will vary in length from 25 to 250 pages. Analytic charts allow you and your physicians to see at a glance your medication options—including new, promising, off-label and experimental all rated for clinical efficacy.

Free Updates for 1 Year
All 6 Outcomes
Top 200 Key Drugs and Biologics
Top 50 Key Therapies and Procedures
Detailed History Charts
Full Research Reference Details
Sample PDF Report on Psoriasis >>

Price:

$24.00 & Delivery via PDF download
updates for 1 year

Research Interface

Rapidly retrieve summaries of all the evidence for any disease in seconds. Save hours of search and analysis time. CureHunter is unlike any "search engine" you have ever used. Where standard "search engines" produce lists of links, CureHunter quantifies evidence, extracts it from the literature and calculates a result you can use to immediately facilitate evidence based decision making in Real Clinical Time.

Unlimited Disease, Drug and Therapy Search
2 clicks from Disease to Drug to Evidence
Trial References
All the Positive Outcomes
Detailed Relationship Timeline Charts
Full Article Reference Details
Includes Mobile Interface Subscription
One-click to FDA Products/Patents
Request Institution License Details >>

Price:

$490.00 access via web interface
1 year subscription

Proceed to Checkout >>

Mobile Interface

Retrieve summaries of all the evidence for any disease from your Mobile Phone or PDA. Accelerate decision making in the field. Speed up your study of new drug and disease domains. Refresh your knowledge on the road.

Access from any web enabled PDA or Phone
Trial references
All the Positive Outcomes
Drug and Therapy searches
Full Article Reference Details
Try Mobile Interface >>

Price:

$45.00 access via "curehunter.com/m"
1 year subscription

Proceed to Checkout >>