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Thymus Hyperplasia

Enlargement of the thymus. A condition described in the late 1940's and 1950's as pathological thymic hypertrophy was status thymolymphaticus and was treated with radiotherapy. Unnecessary removal of the thymus was also practiced. It later became apparent that the thymus undergoes normal physiological hypertrophy, reaching a maximum at puberty and involuting thereafter. The concept of status thymolymphaticus has been abandoned. Thymus hyperplasia is present in two thirds of all patients with myasthenia gravis. (From Segen, Dictionary of Modern Medicine, 1992; Cecil Textbook of Medicine, 19th ed, p1486)
Also Known As:
Hyperplasia of Thymus Gland; Thymic Hyperplasia; Gland Hyperplasia, Thymus; Gland Hyperplasias, Thymus; Hyperplasia, Thymic; Hyperplasia, Thymus; Hyperplasias, Thymic; Thymic Hyperplasias; Thymus Gland Hyperplasia; Thymus Gland Hyperplasias
Networked: 335 relevant articles (26 outcomes, 18 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Thymoma (Thymic Carcinoma)
2. Myasthenia Gravis
3. Neoplasms (Cancer)
4. Hodgkin Disease (Hodgkin's Disease)
5. Hyperthyroidism

Experts

1. Berrih-Aknin, Sonia: 9 articles (01/2018 - 05/2005)
2. Le Panse, Rozen: 8 articles (01/2018 - 12/2006)
3. Nagane, Yuriko: 4 articles (01/2018 - 01/2003)
4. Utsugisawa, Kimiaki: 4 articles (01/2018 - 01/2003)
5. Suzuki, Yasushi: 4 articles (11/2016 - 10/2005)
6. Bismuth, Jacky: 4 articles (03/2013 - 12/2006)
7. Imai, Tomihiro: 3 articles (01/2018 - 01/2014)
8. Murai, Hiroyuki: 3 articles (01/2018 - 01/2014)
9. Ding, Chong-Yang: 3 articles (05/2016 - 01/2015)
10. Fan, Lei: 3 articles (05/2016 - 01/2015)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Thymus Hyperplasia:
1. Cholinesterase Inhibitors (Anticholinesterases)IBA
2. AntibodiesIBA
3. Antithyroid Agents (Antithyroid Drugs)IBA
4. Prednisolone (Predate)FDA LinkGeneric
5. Immunosuppressive Agents (Immunosuppressants)IBA
6. Intravenous Immunoglobulins (IVIG)FDA Link
7. MethylprednisoloneFDA LinkGeneric
8. Fluorodeoxyglucose F18 (Fludeoxyglucose F 18)FDA Link
9. Tumor Viral Antigens (Large T Antigen)IBA
10. LigandsIBA

Therapies and Procedures

1. Thymectomy
2. Drug Therapy (Chemotherapy)
3. Therapeutics
4. Plasmapheresis
5. Castration