|5.||Venous Thrombosis (Deep-Vein Thrombosis)
|1.||Stone, Gregg W: 196 articles (12/2015 - 01/2002)|
|2.||Serruys, Patrick W: 177 articles (12/2015 - 06/2002)|
|3.||Mehran, Roxana: 134 articles (12/2015 - 01/2002)|
|4.||Waksman, Ron: 129 articles (12/2015 - 01/2002)|
|5.||Colombo, Antonio: 113 articles (11/2015 - 01/2002)|
|6.||Windecker, Stephan: 101 articles (11/2015 - 03/2002)|
|7.||Kastrati, Adnan: 94 articles (12/2015 - 06/2002)|
|8.||Leon, Martin B: 79 articles (08/2015 - 01/2002)|
|9.||Xu, Bo: 78 articles (12/2015 - 03/2005)|
|10.||Torguson, Rebecca: 76 articles (12/2015 - 10/2004)|
|1.||Heparin (Liquaemin)FDA LinkGeneric
04/01/2002 - "Although various types of heparin coatings were effective in reducing (sub)acute thrombosis, most of them failed to reduce neointimal proliferation. "
01/01/1999 - "Unfractionated heparin (UH), administered subcutaneously in low doses of 5000 U every 12 h, is safe and effective in preventing thrombosis in most patients. "
01/01/1994 - "In the event of a marked decrease in platelet count associated with venous or arterial thrombosis, heparin therapy should be stopped immediately. "
05/01/2002 - "With improved surgical techniques, the use of heparin-based thromboprophylactic agents has allowed significant advances in the prevention of thrombosis during the past 30 years. "
10/01/1994 - "Right atrial thrombus can be treated successfully with heparin, leading to its resolution and a normal pregnancy outcome."
|2.||Aspirin (Acetylsalicylic Acid)FDA LinkGeneric
05/01/1999 - "Aspirin-treated blood perfused under normoxic conditions showed a marked decrease in thrombus with a concomitant increase in both platelet adhesion and covered surface percentages. "
08/15/2009 - "Aspirin reaction units were significantly greater in the DES thrombosis population. "
01/01/1997 - "These investigations created a favorable scenario for launching a European collaborative clinical trial (ECLAP study) aimed at testing the efficacy of low-dose aspirin in preventing thrombosis and prolonging survival in patients with PV."
08/04/2015 - "If left untreated both microvascular and major thrombosis frequently do occur in MPN-T, but can easily be cured and prevented by low dose aspirin as platelet counts are above 350 × 10(9)/L. "
07/01/2012 - "General lack of TF expression by neoplastic plasma cells may explain why thrombosis is not predictive of poor outcome, and why aspirin prophylaxis is often effective in MM."
|3.||glucuronyl glucosamine glycan sulfate (Vessel)IBA
07/01/2014 - "There is controversy concerning the most effective treatment of portal vein thrombosis, which is based on information that is seldom robust and whose primary objective is to achieve a return to vessel patency. "
09/01/2012 - "The best treatment for patients with Behçet's disease (BD) with major vessel thrombosis has not been fully determined. "
04/01/2013 - "The diameter and flow volume in the largest collateral vessel at the time of thrombus detection were significantly smaller in the improved patients than the others. "
11/15/1996 - "At 90 minutes, patients with TIMI grade 2 flow had greater infarct vessel narrowing and a significantly greater incidence of thrombus than patients with TIMI grade 3 flow. "
07/10/1992 - "Evaluation of 21h and representative analogues in vivo using a rabbit model of small vessel thrombosis revealed significantly greater antithrombotic efficacy compared to that of previously studied compounds with similar intrinsic biological activity measured in vitro but inferior aqueous solubility."
|4.||Warfarin (Coumadin)FDA LinkGeneric
01/01/1999 - "Warfarin is very effective in preventing exacerbation of portal vein thrombosis in PNH."
10/01/2008 - "To evaluate the efficacy of prophylactic use of warfarin in patients with high risk of lead-associated thrombosis. "
03/22/2006 - "Here is a case where the right coronary artery is filled with thrombus and has been successfully treated with warfarin."
09/18/2003 - "Our objective was to show that high-intensity warfarin was more effective in preventing thrombosis than moderate-intensity warfarin. "
11/30/1999 - "Continued medication with warfarin during pregnancy will offer her a reasonable good protection against thrombosis, but carries a considerable risk of teratogenic effects. "
|5.||Low-Molecular-Weight Heparin (Heparin, Low Molecular Weight)IBA
06/01/2002 - "Successful management of acute portal vein thrombosis by low molecular weight heparin and oral anticoagulation."
07/30/1994 - "A significant reduction in the incidence of thrombus extension (common odds ratio 0.51, 95% confidence interval 0.32 to 0.83; P = 0.006) in favour of low molecular weight heparin was observed. "
09/01/2001 - "For other patients at higher risk of thrombosis, "bridging therapy" with outpatient low molecular weight heparin is safe and effective. "
09/01/1998 - "The main objective of the study presented was to test if thrombus regression can be improved by treatment with an intravenously or subcutaneously administered low molecular weight heparin (LMWH). "
03/01/2000 - "In adults, subcutaneous low-molecular-weight heparin (LMWH) is as effective as UFH in the treatment of thrombosis. "
02/01/2012 - "It also has a potent inhibitory effect on thrombin-induced platelet aggregation, making it effective in preventing both venous and arterial thrombosis. "
01/01/2003 - "While the in vitro results with ODN 2 were consistent with thrombus imaging, the rapid clearance of ODN 2 from circulation, combined with slow mass transfer in the clot, seem to work against in vivo thrombin-dependent imaging or washout analysis."
11/01/2008 - "ELISA and immunohistochemistry assay were used to study the improved thrombus selectivity of SFH and the results showed that SFH, compared with SAK, displayed higher affinity for thrombin and thrombin-rich thrombus. "
07/01/2015 - "Ecotin-RR was more effective in inhibiting thrombin than ecotin-WT. Both ecotins presented similar mechanisms of anticoagulation activity and were able to decrease thrombus formation. "
07/30/2010 - "These data show for the first time that: (i) STIM1 and Orai1 jointly contribute to GPVI-induced SOCE, procoagulant activity, and thrombus formation; (ii) a compensating Ca(2+) entry pathway is effective in the additional presence of thrombin; (iii) platelets contain two mechanisms of Ca(2+) entry and PS exposure, only one relying on STIM1-Orai1 interaction."
|7.||Urokinase-Type Plasminogen Activator (Urokinase)FDA Link
06/05/2012 - "Recurrent episodes of PV and SMV thrombosis were observed in 2 (4.4%) patients at 6 months and 5 years respectively post-discharge and they were treated successfully with urokinase infusion. "
01/01/2002 - "Currently available data fail to provide compelling evidence that newer PAs offer significantly greater efficacy and safety than well-established agents like urokinase when used to treat peripheral vascular thrombosis."
05/01/1995 - "A subsequently developing thrombosis of the left V. femoralis was treated successfully with urokinase. "
05/01/1992 - "These findings suggest that intracoronary urokinase can be effective in reducing early restenosis in patients with angiographic residual thrombus after successful direct PTCA. "
02/01/1991 - "Urokinase was readministered and two showed significant reduction in the thrombus. "
|8.||clopidogrel (Plavix)FDA Link
08/15/2009 - "The results of the VASP-P assay did not correlate with the presence of ST. In conclusion, patients who experienced DES thrombosis demonstrated significantly greater rates of clopidogrel resistance as determined by P2Y12 reaction units, but not VASP-P, compared with patients without DES thrombosis. "
11/01/1995 - "Clopidogrel may be beneficial in the prevention of arterial thrombosis."
01/01/2015 - "This study protocol amendment was made in response to a large trial demonstrating that clopidogrel is effective in safely preventing primary AVF thrombosis, but ineffective at increasing functional patency. "
01/01/2009 - "Recently a placebo-controlled trial has shown that clopidogrel is effective in safely preventing primary AVF thrombosis, but ineffective at increasing functional patency. "
02/01/2002 - "In this review we analyze: 1) the composition of coronary thrombi in patients with ACS, 2) the mechanisms of thrombus development and growth, 3) the mechanisms of platelet adhesion and aggregation, 4) the characteristics of clopidogrel, 5) the efficacy of the various therapeutic strategies, 6) the possible implications of the adjunctive therapy with clopidogrel for the treatment and prevention of cardiovascular events in ACS with no ST-segment elevation."
|9.||Tissue Plasminogen Activator (Alteplase)FDA Link
09/01/2015 - "This case report describes a pregnant patient, whose echocardiogram showed evident gradient increase on her mechanical prosthetic mitral valve, and who was treated successfully with tissue plasminogen activator for mechanical valve thrombosis. "
09/01/2013 - "A neonatal thrombosis patient treated successfully with recombinant tissue plasminogen activator."
02/01/1995 - "Prosthetic valve thrombosis, a rare but fatal complication, can be successfully treated with tissue-type plasminogen activator and monitored by transthoracic and transesophageal echocardiography."
11/01/1989 - "We conclude that local infusion of tissue-type plasminogen activator is effective in lysing thromboses that may occur at the venous microvascular anastomotic site without significant activation of systemic fibrinolysis."
05/01/2013 - "Nanoparticle thrombus imaging was also effective in monitoring the therapeutic efficacy of thrombolysis (n=118 tissue plasminogen activator [tPA] therapies). "
01/01/2012 - "We describe a primigravida with mitral valve replacement status presenting with acute prosthetic valve thrombosis and treated successfully with intravenous streptokinase."
06/01/2006 - "Acute portal vein thrombosis with associated mesenteric and splenic vein thrombosis is a potentially lethal coagulation disorder that can be treated successfully with systemic streptokinase."
09/01/2005 - "The case is presented of a patient in whom prosthetic heart valve thrombosis was treated successfully with streptokinase under transesophageal echocardiographic guidance."
12/01/1994 - "Streptokinase infused directly into thrombus in arteries even in low doses significantly enhances thrombolysis of vessels which are too small to be cleared by mechanical means. "
08/01/1991 - "A 27 year old patient with a thrombosis of the subclavian vein (Paget- von Schroetter's-syndrome) was treated successfully with a systemic streptokinase thrombolysis. "
08/01/1996 - "The present study shows that current anticoagulation treatment is inefficient in suppressing platelet activation in patients with coronary stents and, therefore, might not be the best treatment for reducing the incidence of subacute stent thrombosis."
05/01/2011 - "The modified possible criteria eliminated 13 false positive cases (specificity = 49%) and was the best approximation of a hypothetical gold standard in a sensitivity analysis if late death represented at least 20% of all stent thrombosis cases. "
02/01/2011 - "Despite improved stent implantation technologies and effective antiplatelet regimens, stent thrombosis has been one of the most important problem in percutaneous coronary intervention. "
04/01/2007 - "This strategy is highly effective in prevention of stent thrombosis until its struts are covered with endothelium. "
10/29/2006 - "The dual antiplatelet therapy and the high pressure stent implantation technique dramatically reduced the incidence of subacute stent thrombosis. "
01/01/2014 - "This analysis could not examine the potential role of technical factors during implant, such as sub-optimal pump or graft positioning, changes in patient management paradigms with pump speed settings, improved recognition and change in the threshold for pump exchange, or design or production changes with the pump, as contributors to the risk of pump thrombosis."
01/01/2000 - "A surveillance program helped prevent graft thrombosis, and intervention as required achieved excellent primary and assisted patency rates. "
01/01/2000 - "The improved visualization and contrast enhancement were more marked in the grafts that contained thrombus nonhyperechoic to surrounding soft tissues. "
09/15/1994 - "Despite overall improved graft survival, renal graft thrombosis (RGT) remains an important cause of graft loss. "
09/01/1991 - "Occlusive thrombus was cleared in 12 of 13 patients with native artery occlusion (7 complete, 5 partial), 8 of 9 with autologous vein grafts (5 complete, 3 partial), and in all 18 patients with synthetic grafts (17 complete, 1 partial). "
02/29/2008 - "However, we report a remarkable case during which we were able to successfully aspirate a 31 mm continuous length of thrombus using an Export catheter with subsequent dramatic improvement in both TIMI-flow and ST-segment resolution."
11/01/2007 - "Umbilical venous catheter-associated thrombosis is common, and spontaneous resolution occurs in most cases."
01/01/2006 - "The best results in the removal of thrombotic material were obtained by manual aspiration of the thrombus using a catheter (90% success). "
06/01/2003 - "When systemic anticoagulation has failed, percutaneous catheter-directed thrombolytic infusion appears to be effective in the treatment of most patients with severe ischemic hand symptoms due to thrombosis after radial artery cannulation."
06/01/2013 - "However, recent advances in catheter-based interventions have led to the development of a variety of minimally invasive endovascular strategies to remove venous thrombus and accepted as an important first-line treatment given its high overall success rate and low morbidity as compared with medical and surgical treatments. "
03/01/2003 - "Thrombectomy with X-Sizer and Rescue improved the angiographic thrombus image in most cases and was associated to a low complication rate. "
11/01/2002 - "The advent of improved interventional, endovascular, and pharmacomechanical techniques for the treatment of thrombosis has raised questions as to whether surgical thrombectomy is the most effective treatment. "
09/01/2002 - "Thus, rheolytic thrombectomy resulted in significant reduction of the thrombus burden in most patients, restored TIMI-3 flow, and led to favorable short- and long-term outcomes."
12/01/2009 - "He was found to have an adherent thrombus on the eustachian valve and his symptoms resolved completely following surgical thrombectomy. "
03/01/2000 - "Angiographic study demonstrated late thrombosis, which were treated successfully with the Angiojet thrombectomy device."
|5.||Angioplasty (Angioplasty, Transluminal)
01/01/1985 - "SILDT is most effective in acute arterial thrombosis complicating arteriography or percutaneous angioplasty. "
02/01/1993 - "Of the patients with complete or partial clearance of thrombosis, 19 had no underlying apparent cause, 23 underwent angioplasty and 15 had an operation. "
03/01/2014 - "Aortic thrombus was successfully eliminated with CDT in four patients before percutaneous transluminal angioplasty (PTA) and stenting. "
11/01/2011 - "This case demonstrated that in the absence of occlusive lesion, thrombus aspiration alone without angioplasty or stenting is safe and effective with good clinical outcome."
04/05/2010 - "The aim of this study was to investigate whether this combined strategy is superior to thrombus aspiration alone in improving myocardial perfusion in patients with STEMI undergoing primary angioplasty. "