A congenital bleeding disorder with prolonged bleeding time, absence of aggregation of platelets in response to most agents, especially ADP, and impaired or absent clot retraction. Platelet membranes are deficient in or have a defect in the glycoprotein IIb-IIIa complex (PLATELET GLYCOPROTEIN GPIIB-IIIA COMPLEX).
Also Known As:
Glanzmann Thrombasthenia; Deficiency of GP 2b 3a Complex; GP IIb-IIIa Complex, Deficiency Of; Glanzmann Thrombasthenia, Type A; Glycoprotein Complex IIb-IIIa, Deficiency Of; Platelet Fibrinogen Receptor, Deficiency of; Platelet Glycoprotein 2b-3a Deficiency; Platelet Glycoprotein IIb-IIIa Deficiency; Thrombasthenia of Glanzmann and Naegeli; GP IIb IIIa Complex, Deficiency Of; Glycoprotein Complex IIb IIIa, Deficiency Of; Platelet Glycoprotein 2b 3a Deficiency; Platelet Glycoprotein IIb IIIa Deficiency; Thrombasthenia, Glanzmann; Thrombasthenias