Thoracic Outlet Syndrome (Syndrome, Thoracic Outlet)

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81 relevant articles (7 outcomes, 6 trials/studies) found for this Disease

Description: A neurovascular syndrome associated with compression of the BRACHIAL PLEXUS; SUBCLAVIAN ARTERY; and SUBCLAVIAN VEIN at the superior thoracic outlet. This may result from a variety of anomalies such as a cervical rib (CERVICAL RIB SYNDROME), anomalous fascial bands, and abnormalities of the origin or insertion of the anterior or medial scalene muscles. Clinical features may include pain in the shoulder and neck region which radiates into the arm, PARESIS or PARALYSIS of brachial plexus innervated muscles, PARESTHESIA, loss of sensation, reduction of arterial pulses in the affected extremity, ISCHEMIA, and EDEMA. (Adams et al., Principles of Neurology, 6th ed, pp214-5).

Also Known As:

Syndrome, Thoracic Outlet; Aperture Syndrome, Thoracic Outlet; Arterial Thoracic Outlet Syndrome; Nerve Compression Syndrome, Thoracic Outlet; Neurogenic Thoracic Outlet Syndrome; Neurologic Syndrome, Thoracic Outlet; Superior Thoracic Aperture Syndrome; Thoracic Outlet Neurologic Syndrome; Thoracic Outlet Neurovascular Syndrome; Thoracic Outlet Syndrome, Neurogenic; Venous Thoracic Outlet Syndrome; Costoclavicular Syndromes; Outlet Syndrome, Thoracic; Outlet Syndromes, Thoracic; Syndrome, Costoclavicular; Syndrome, Scalenus Anticus; Syndromes, Costoclavicular; Syndromes, Thoracic Outlet; Thoracic Outlet Syndromes; Costoclavicular Syndrome; Neurovascular Syndrome, Thoracic Outlet; Scalenus Anticus Syndrome; Thoracic Outlet Nerve Compression Syndrome

Relationship Network

Disease Context: Research Results

Nervous System Diseases: 3422

Neuromuscular Diseases: 744

Peripheral Nervous System Diseases: 3233

Nerve Compression Syndromes: 111

Thoracic Outlet Syndrome: 81

Cervical Rib Syndrome

Cardiovascular Diseases: 18525

Vascular Diseases: 7184

Thoracic Outlet Syndrome: 81

Cervical Rib Syndrome

Related Diseases

1.	Thrombosis (Thrombus)
2.	Chest Pain (Chest Pains)
3.	Peptic Esophagitis (Reflux Esophagitis)
4.	Cardiovascular Diseases (Cardiovascular Disease)
5.	Syndrome

Experts

1.	Gordon, Roy L: 2 articles (10/2004 - 04/2003)
2.	Messina, Louis M: 2 articles (10/2004 - 04/2003)
3.	Kerlan, Robert K: 2 articles (10/2004 - 04/2003)
4.	Schneider, Darren B: 2 articles (10/2004 - 04/2003)
5.	Eichler, Charles M: 2 articles (10/2004 - 04/2003)
6.	Hammond, Sharon L: 1 article (12/2007)
7.	Sanders, Richard J: 1 article (12/2007)
8.	Rao, Neal M: 1 article (12/2007)
9.	Garcarek, Jerzy: 1 article (01/2007)
10.	Pupka, Artur: 1 article (01/2007)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Thoracic Outlet Syndrome:

1.	Triad FDA Link 08/01/1981 - "While cardiovascular diseases have by far the most serious consequences for patients with chest pain, the high incidence of association between cardiovascular diseases, reflux esophagitis, and thoracic outlet syndrome comprises a triad helpful for the etiologic diagnosis of chest pain." Order ALL the reference details at left...
2.	tebufenozide (Mimic)IBA 03/01/1994 - "Thoracic outlet syndrome (TOS) may mimic other more common causes of shoulder and arm symptoms" 06/01/1995 - "Electrodiagnostic studies may objectively document the presence of median neuropathy within the carpal tunnel and help distinguish CTS from other disorders such as cervical radiculopathy, neurogenic thoracic outlet syndrome, proximal median nerve compression syndromes, and polyneuropathy which may either mimic or occasionally coexist with CTS" Order ALL the reference details at left...
3.	SeprafilmIBA 12/01/2007 - "Observations on the use of seprafilm on the brachial plexus in 249 operations for neurogenic thoracic outlet syndrome." 12/01/2007 - "Seprafilm was employed in this study to see if it would reduce postoperative scarring after supraclavicular thoracic outlet decompression for neurogenic thoracic outlet syndrome (NTOS)" Order ALL the reference details at left...
4.	glucuronyl glucosamine glycan sulfate (Vessel)IBA 11/01/1979 - "1. In thoracic outlet-syndrome arterial lesions--such as poststenotic aneurysm with or without peripheral arterial emboli--are mostly caused by permanent compression of the vessel" 08/01/2000 - "Such pathology includes digital vessel thrombosis, proximal thrombosis with distal embolization, vessel aneurysm, and vessel compression, such as in thoracic outlet syndrome and quadrilateral space syndrome" Order ALL the reference details at left...
5.	Botulinum Toxin Type A (Botox)FDA Link 11/01/2008 - "A 28-yr-old man, diagnosed with vascular thoracic outlet syndrome, had his right anterior scalene muscle injected with botulinum toxin type A under ultrasound guidance" 11/01/2008 - "Botulinum toxin type A improves blood flow in vascular thoracic outlet syndrome." Order ALL the reference details at left...
6.	Urinary Plasminogen Activator (Urokinase)FDA LinkGeneric 04/01/1988 - "Treatment of a case of thromboembolism resulting from thoracic outlet syndrome with intra-arterial urokinase infusion." 04/01/1988 - "A 36-year-old man with thoracic outlet syndrome, admitted to the hospital with digital ischemia from subclavian artery thrombosis and distal embolization, was given intra-arterial urokinase" Order ALL the reference details at left...
7.	Stainless Steel (Steel, Stainless)IBA 03/01/2006 - "3) Shorter thick stainless-steel AO bars were selected to avoid thoracic outlet syndrome and restriction" Order ALL the reference details at left...
8.	DiureticsIBA 10/01/1981 - "In sum, both the carpal tunnel syndrome and the thoracic outlet syndrome quickly resolved when treatment with diuretics was extended the patient for a short period of time premenstrually." Order ALL the reference details at left...
9.	Creatine Kinase (Creatine Phosphokinase)IBA 03/01/1983 - "Four patients with elevated creatine phosphokinase (CPK) values and recurrent chest pain were found to have thoracic outlet syndrome" 03/01/1983 - "Thoracic outlet syndrome mimicking angina pectoris with elevated creatine phosphokinase values." Order ALL the reference details at left...
10.	CollagenIBA 08/01/1985 - "A history or physical findings consistent with collagen vascular disease, obstructive arterial disease, or carpal tunnel or thoracic outlet syndrome should lead to selected diagnostic tests" Order ALL the reference details at left...

Therapies and Procedures

1.	Decompression 04/01/2004 - "BACKGROUND: Although 90% of patients with neurogenic thoracic outlet syndrome (NTOS) experience "excellent" or "good" results after thoracic outlet decompression, recurrent symptoms may develop in certain patients" 10/01/2005 - "The purpose of this study was to assess the results of decompression of the thoracic outlet due to scalenus anticus syndrome and thus to give recommendation for a safe and effective surgical treatment" 05/01/1999 - "The purpose of this study was to assess the symptomatic outcome of patients with thoracic outlet syndrome who underwent decompression of the thoracic outlet" 07/01/2005 - "OBJECTIVE: To evaluate the pattern of clinical results in patients with neurogenic thoracic outlet syndrome (N-TOS) after operative decompression and longitudinal follow-up" 07/01/2005 - "Thoracic outlet syndrome: pattern of clinical success after operative decompression." Order ALL the reference details at left...
2.	Aftercare (After-Treatment) 05/01/2007 - "OBJECTIVE: The present study was undertaken to determine which factors differentiate patients with a good outcome after treatment for Thoracic Outlet Syndrome (TOS) from patients with a poor outcome" Order ALL the reference details at left...
3.	Surgical Decompression 07/01/2000 - "Patients with thoracic outlet syndrome (TOS) who improve temporarily after anesthetic blockade of the anterior scalene muscles have been shown to improve after ultimate surgical decompressions at the interscalene triangle" 04/01/2003 - "CONCLUSIONS: Surgical decompression for thoracic outlet syndrome is efficient and dependable, but results deteriorate over time." 02/01/2001 - "CONCLUSION: Thrombolysis, anticoagulation, surgical decompression, and endovascular procedures act synergistically to improve results of therapy in patients with vascular thoracic outlet syndrome." 10/01/1997 - "These results show that surgical decompression for thoracic outlet syndrome is a worthwhile procedure and is associated with relatively few complications." 10/01/1997 - "Surgical decompression of thoracic outlet syndrome; is it a worthwhile procedure?" Order ALL the reference details at left...
4.	Thrombolytic Therapy 09/01/2005 - "Immediate thrombolytic therapy followed by early surgical decompression has also been suggested previously, but has only recently been shown to be safe and efficacious, while significantly decreasing the duration of disability suffered by patients with this form of thoracic outlet syndrome" 05/01/1993 - "In addition, Doppler sonography shows promise for monitoring thrombolytic therapy after "effort thrombosis" and detecting intermittent venous compression related to thoracic outlet syndrome." 07/01/1997 - "From March 1989 to March 1993, six athletic patients were treated in our institution by thrombolytic therapy for acute effort axillary-subclavian vein thrombosis in thoracic outlet syndrome" 04/01/2003 - "CONCLUSIONS: Thrombus debulking or removal with percutaneous mechanical thrombectomy devices may reduce the amount or duration of thrombolytic therapy required, making treatment of venous thoracic outlet syndrome safer" Order ALL the reference details at left...
5.	Sympathectomy (Sympathectomies) 09/01/1993 - "Dorsal sympathectomy and the management of the thoracic outlet syndrome have been considerably improved with the use of video assistance because it affords both magnification and an improved light system" 09/01/1993 - "In 326 patients, sympathectomy, performed either alone or in conjunction with first-rib removal for relief of the thoracic outlet syndrome, has been successful" 09/01/1993 - "Dorsal sympathectomy and management of thoracic outlet syndrome with VATS." 04/01/1996 - "For recurrent thoracic outlet syndrome and sympathetic maintained pain syndrome, a high thoracoplasty posterior approach is preferable with neurolysis of the nerve roots and brachial plexus as well as a dorsal sympathectomy" Order ALL the reference details at left...

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