|1.||de Boer, Nanne K H: 8 articles (04/2011 - 04/2005)|
|2.||Relling, Mary V: 6 articles (06/2015 - 06/2003)|
|3.||Evans, William E: 6 articles (06/2015 - 06/2003)|
|4.||van Bodegraven, A A: 6 articles (02/2014 - 09/2005)|
|5.||de Boer, N K H: 6 articles (06/2010 - 04/2005)|
|6.||Reinisch, Walter: 5 articles (03/2015 - 08/2005)|
|7.||Gilissen, L P L: 5 articles (02/2014 - 02/2007)|
|8.||Engels, L G J B: 5 articles (02/2014 - 02/2007)|
|9.||Hooymans, P M: 5 articles (02/2014 - 02/2007)|
|10.||Mulder, Chris J J: 5 articles (09/2010 - 01/2003)|
|1.||Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
01/01/2009 - "Thioguanine pharmacokinetics in induction therapy of children with acute myeloid leukemia."
11/01/2005 - "We present a case of NEH in a 70-year-old neutropenic male who received thioguanine for acute myeloid leukemia. "
08/01/2002 - "The antimetabolite 6-thioguanine (6-TG) is utilized in the management of acute myelogenous leukemia (AML). "
06/01/1985 - "Treatment of acute myelocytic leukemia with a daunorubicin-cytarabine-6 thioguanine regimen without maintenance therapy."
01/01/1985 - "All drugs used commonly in the treatment of ANLL, except 6-thioguanine, were evaluated singly and some in combination. "
|2.||Inflammatory Bowel Diseases (Inflammatory Bowel Disease)
01/01/2003 - "6-thioguanine: a new old drug to procure remission in inflammatory bowel disease."
02/01/2007 - "Patients attending the inflammatory bowel disease clinic who were started on 6-thioguanine therapy were included in this prospective observational study. "
02/01/2007 - "The aim of this study was to analyse our experience of the efficacy and safety of 6-thioguanine in inflammatory bowel disease. "
01/01/2004 - "To study liver biopsies from 3 patients with inflammatory bowel disease who had received thioguanine for more than a year, and who had elevated serum liver enzyme values and underwent percutaneous liver biopsy. "
08/01/2015 - "Body Mass Index and Smoking Affect Thioguanine Nucleotide Levels in Inflammatory Bowel Disease."
|3.||Psoriasis (Pustulosis Palmaris et Plantaris)
11/01/2002 - "6-Thioguanine has been highly effective in treating and maintaining improvement in patients with psoriasis. "
04/01/1999 - "Marked improvement of recalcitrant psoriasis was noted in 10 (71%) of 14 patients receiving thioguanine therapy using a pulse-dosing schedule. "
01/01/2001 - "Thioguanine appears to be an effective treatment for patients with severe recalcitrant psoriasis. "
12/01/1999 - "6-Thioguanine is effective for the treatment of moderate to severe plaque-type psoriasis, and may be safe when given for defined periods and with careful hematologic monitoring. "
12/01/1999 - "To test the hypothesis that the antimetabolite 6-thioguanine (Sigma-Aldrich, St Louis, Mo) might be an effective treatment for psoriasis vulgaris because of its antilymphocytic effects. "
|4.||Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia)
12/01/2013 - "6-thioguanine induces mitochondrial dysfunction and oxidative DNA damage in acute lymphoblastic leukemia cells."
09/01/2000 - "6-thioguanine (6TG) is undergoing investigation for use in the maintenance phase of acute lymphoblastic leukemia (ALL). "
01/01/1999 - "Some 6-thioguanine resistant (6-TGr) clones were separated from human T cell acute lymphocytic leukemia, PEER. "
01/01/1982 - "Clinically reversible veno-occlusive disease of the liver developed in a 23-year-old man with acute lymphocytic leukemia after 10 months of maintenance therapy with 6-thioguanine. "
03/01/2001 - "Plasma pharmacokinetics and cerebrospinal fluid penetration of thioguanine in children with acute lymphoblastic leukemia: a collaborative Pediatric Oncology Branch, NCI, and Children's Cancer Group study."
|5.||Crohn Disease (Crohn's Disease)
06/15/2003 - "In responders to tioguanine, the drug appears to be very effective in maintaining remission of chronic active Crohn's disease. "
02/15/2003 - ": In this patient group with chronic active Crohn's disease, 6-thioguanine appeared to be effective with acceptable short-term toxicity, but long-term controlled trials are clearly needed to further define its role."
06/15/2003 - "To evaluate the role of tioguanine in the maintenance of remission in chronic active Crohn's disease. "
06/15/2003 - "Remission maintenance by tioguanine in chronic active Crohn's disease."
10/01/2010 - "ECCO consensus: evidence-based use of 6-thioguanine therapy in Crohn's disease?"
|9.||Etoposide (VP 16)
|1.||Drug Therapy (Chemotherapy)
|3.||Heterologous Transplantation (Xenotransplantation)