|1.||Soares, Maria I L: 3 articles (05/2014 - 10/2010)|
|2.||Botelho, M Filomena: 3 articles (05/2014 - 10/2010)|
|3.||Laranjo, Mafalda: 3 articles (05/2014 - 10/2010)|
|4.||Abrantes, Ana Margarida: 2 articles (05/2014 - 10/2010)|
|5.||Pinho e Melo, Teresa M V D: 2 articles (05/2014 - 02/2013)|
|6.||Brito, Ana Filipa: 2 articles (02/2013 - 10/2010)|
|7.||Paixão, José A: 2 articles (02/2013 - 10/2010)|
|8.||Gabay, Martín: 1 article (07/2015)|
|9.||Cruces, Eugenia: 1 article (07/2015)|
|10.||Aguirre-López, Beatriz: 1 article (07/2015)|
05/22/2014 - "Further studies on 6,7-bis(hydroxymethyl)-1H,3H-pyrrolo[1,2-c]thiazoles as anticancer agents against breast cancer are reported, allowing to demonstrate the potential of these compounds for the therapy of the triple-negative breast cancer, the most challenging tumors in clinical practice. "
05/01/2013 - "The in vitro growth inhibitory activity of 26 thiazoles (including 4-halogeno-2,5-disubtituted-1,3-thiazoles) and 5 thienothiazoles was assessed on a panel of 6 human cancer cell lines, including glioma cell lines. "
10/01/2010 - "New chiral 1H,3H-pyrrolo[1,2-c]thiazoles were synthesized and screened for their in vitro activity as anti-cancer agents in three human tumor cell lines, colorectal adenocarcinoma, melanoma and breast adenocarcinoma. "
08/01/1999 - "The compounds are cationic derivatives of phenyl-substituted thiazoles which inhibit the calmodulin stimulation of cyclic-AMP phosphodiesterase and are active against animal tumor cells in culture. "
|2.||Breast Neoplasms (Breast Cancer)
01/01/2015 - "These results suggested that the new series of hybridation of aryl-thiazoles and aminopyrimidines could be identified and developed as novel highly potential anticancer agents against the triple-negative breast cancer as well as metastatic one in the future. "
05/22/2014 - "The reported results consolidate the potential of 6,7-bis(hydroxymethyl)-1H,3H-pyrrolo[1,2-c]thiazoles for the therapy of breast cancer, particularly the triple-negative. "
05/22/2014 - "Targeting triple-negative breast cancer cells with 6,7-bis(hydroxymethyl)-1H,3H-pyrrolo[1,2-c]thiazoles."
02/01/2013 - "The synthesis and biological evaluation of 6,7-bis(hydroxymethyl)-1H,3H-pyrrolo[1,2-c]thiazoles as anticancer agents against MCF7 breast cancer cell lines is reported. "
02/01/2013 - "Chiral 6,7-bis(hydroxymethyl)-1H,3H-pyrrolo[1,2-c]thiazoles with anti-breast cancer properties."
12/01/1980 - "A series of 5,6,6a,8,9,11a-hexahydroanaphth[1',2':4,5]imidazo[2,q-b]thiazoles (17 and 20) and 5,6,6a,9,10,11a-hexahydronaphth[2',1':4,5]imidazo[2,1-b]thiazoles has been synthesized with cis- and/or trans-1,2-diamino-1,2,3,4-tetrahydronaphthalenes as the key intermediates and subsequently evaluated for immunological activity (effects on antibody formation and delayed-type hypersensitivity reaction). "
01/01/1994 - "In general, allergy to thiocarbamates was concomitant with allergy to thiurams (20 out of 21 patients allergic to carbamates) and over-sensitivity to thiazoles was very often parallel to allergy to thiurams (8 out of 18 patients allergic to thiazoles). "
01/01/1994 - "In this group (20 workers of the metallurgical industry, 15 health service workers, 6 workers of the building and 3 of the rubber industries, 2 farmers and 5 drivers) the frequency of allergy to 15 accelerators of the thiuram group, thiocarbamates, thiazoles as well as derivatives of diphenylguanidine and thiocarbamide was investigated. "
|4.||Alzheimer Disease (Alzheimer's Disease)
12/15/2012 - "Synthesis and structure-activity relationships of tri-substituted thiazoles as RAGE antagonists for the treatment of Alzheimer's disease."
04/01/2007 - "Clubbed thiazoles by MAOS: a novel approach to cyclin-dependent kinase 5/p25 inhibitors as a potential treatment for Alzheimer's disease."
|5.||Allergic Contact Dermatitis
|2.||Cyclin-Dependent Kinase 5
|3.||Nitric Oxide Synthase (NO Synthase)