Thebaine

A drug that is derived from opium, which contains from 0.3-1.5% thebaine depending on its origin. It produces strychnine-like convulsions rather than narcosis. It may be habit-forming and is a controlled substance (opiate) listed in the U.S. Code of Federal Regulations, Title 21 Part 1308.12 (1985). (From Merck Index, 11th ed)

Also Known As:

Networked: 21 relevant articles (1 outcomes, 2 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Zenk, Meinhart H: 2 articles (09/2004 - 09/2004)
2.	Chen, Hua: 1 article (01/2022)
3.	Ding, Yifan: 1 article (01/2022)
4.	Lei, Panpan: 1 article (01/2022)
5.	Liang, Jinna: 1 article (01/2022)
6.	Liu, Yanhong: 1 article (01/2022)
7.	Ma, Weina: 1 article (01/2022)
8.	Su, Xinyue: 1 article (01/2022)
9.	Karimzadeh, Ghasem: 1 article (01/2021)
10.	Naghavi, Mohammad Reza: 1 article (01/2021)

Related Diseases

1.	Pain (Aches) 06/01/2016 - "Buprenorphine is a semi-synthetic derivative of thebaine; its low concentration is sufficient to provide effective pain relief. " 01/01/2016 - "No Pain, No Thebaine: Opioids in the Emergency Department." 01/01/2023 - "Oxycodone, a semisynthetic thebaine derivative µ-opioid (MOP) receptor agonist, is effective for treating moderate and severe pain in different clinical conditions. " 03/01/2017 - "Oxycodone, a semisynthetic thebaine derivative opioid, is widely used for the relief of moderate to severe pain. "
2.	Poisoning 01/01/2023 - "Despite relatively high thebaine blood concentrations and moderate to severe poisoning, outcomes were favourable with early presentations. " 01/01/2023 - "A cluster of acute thebaine poisonings from non-food grade poppy seeds in the Australian food supply." 01/01/2023 - "Animal studies indicate thebaine has strychnine-like properties, but there is limited literature describing human thebaine poisoning. " 01/01/2023 - "In 2022, poppy seeds high in thebaine entered the Australian food market, and people consuming tea made from these poppy seeds developed poisoning. " 01/01/2023 - "We describe a cluster of acute thebaine poisoning in people ingesting tea made using poppy seeds with high thebaine content that entered the Australian food supply chain. "
3.	Chronic Pain 09/01/1986 - "Analgesic studies of buprenorphine, a thebaine derivative and potent partial narcotic agonist, were carried out in patients with cancer who had postoperative or chronic pain. "
4.	Neoplasms (Cancer) 09/01/1986 - "Analgesic studies of buprenorphine, a thebaine derivative and potent partial narcotic agonist, were carried out in patients with cancer who had postoperative or chronic pain. "
5.	Acute Kidney Injury (Acute Renal Failure) 01/01/2023 - "It is possible that acute kidney injury prolongs the apparent elimination half-life of thebaine." 01/01/2023 - "Convulsions, acute kidney injury, metabolic acidosis, and cardiac arrest were associated with increasing median thebaine concentrations. "

Related Drugs and Biologics

1.	Opioid Analgesics (Opioids)
2.	Oxycodone (Oxycontin)
3.	Buprenorphine (Subutex)
4.	Analgesics (Analgesic Drugs)
5.	Strychnine
6.	Narcotics (Narcotic Analgesics)
7.	Morphine (MS Contin)
8.	Alkaloids
9.	oripavine
10.	Tea