Thalidomide (Thalomid)
2518
relevant articles (359 outcomes,
484 trials/studies)
found for this Drug
Description:
A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppresive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
Also Known As:
Thalomid; Celgene Brand of Thalidomide; Sedoval; 1H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-
Relationship Network
Drug Context: Research Results