|1.||Hwang, Deng-Fwu: 7 articles (05/2011 - 02/2002)|
|2.||Deeds, Jonathan R: 4 articles (01/2015 - 10/2006)|
|3.||Nishikawa, Toshio: 4 articles (07/2014 - 07/2002)|
|4.||Isobe, Minoru: 4 articles (07/2014 - 07/2002)|
|5.||Waxman, Stephen G: 4 articles (07/2014 - 04/2004)|
|6.||Cummins, Theodore R: 4 articles (09/2011 - 04/2004)|
|7.||Arakawa, Osamu: 3 articles (04/2013 - 01/2011)|
|8.||Całka, Jarosław: 3 articles (01/2013 - 12/2011)|
|9.||Shryock, John C: 3 articles (04/2011 - 11/2008)|
|10.||Belardinelli, Luiz: 3 articles (04/2011 - 11/2008)|
12/15/2000 - "Evidence from animal models and studies of human sensory nerves demonstrate that tetrodotoxin (TTX)-resistant Na(+) channels are present in sensory neurons and might play an important role in pain conduction and chronic pain. "
12/17/2015 - "Antihyperalgesic effect of tetrodotoxin in rat models of persistent muscle pain."
02/01/2012 - "Tetrodotoxin (TTX) as a therapeutic agent for pain."
03/17/2009 - "The tetrodotoxin-resistant (TTX-R) voltage-gated Na(+) channels Na(v)1.8 and Na(v)1.9 are expressed by a subset of primary sensory neurons and have been implicated in various pain states. "
11/01/2008 - "Evidence supports a role for the tetrodotoxin-sensitive Na(V)1.7 and the tetrodotoxin-resistant Na(V)1.8 in the pathogenesis of pain. "
|2.||Ganglion Cysts (Ganglion)
03/01/2007 - "The heart photoresponse of juveniles was reversibly eliminated by application of tetrodotoxin, which changes the heartbeat from neurogenic to myogenic by suppressing cardiac ganglion activity. "
11/15/1999 - "Nonlinear responses evoked from millimeters beyond the ganglion cell were eliminated by tetrodotoxin. "
10/01/1998 - "This study presents evidence that in the neonatal cat blocking the impulse activity of ganglion cells with the Na+-channel blocker tetrodotoxin (TTX) leads to a loss of the axon-related morphology of astrocytes. "
03/01/2015 - "Tetrodotoxin abolished VEPs at all levels in the visual pathway, confirming successful blockage of ganglion cell activity. "
12/01/2007 - "Effects of continuous sciatic nerve block by tetrodotoxin on growth associated protein-43 expression in dorsal root ganglions of normal and sciatic nerve injury rats."
01/01/2011 - "An electrophysiological study of acute tetrodotoxin poisoning."
09/01/2006 - "Our study results suggest that in severe puffer fish poisoning the toxin (tetrodotoxin) has a complete conduction block effect on myelinated nerve fibers and spares axons, and it appears that the toxin has no effect on the CNS. "
03/01/2005 - "This study confirms that the neurotoxic effects of puffer-fish poisoning can be explained by tetrodotoxin blockade of Na(+) channels. "
10/01/1996 - "Electrophysiological studies on acute tetrodotoxin poisoning: a case report."
12/01/1992 - "This study describes the possibility of active and passive immunization for tetrodotoxin (TTX) poisoning. "
08/01/1994 - "In the present study, we investigated the effects of 10 microM tetrodotoxin (TTX) on ischemia-induced disturbances of ion homeostasis in the isolated perfused rat brain. "
09/15/2009 - "Before ischemia and during reperfusion, hearts were treated with no drug (control) or with the late Na(+) current inhibitors Ran (5 micromol/L) or tetrodotoxin (1 micromol/L). "
10/20/1998 - "Activation patterns of VF in the Langendorff-perfused rabbit heart were studied with the use of 2 protocols: (1) 15 minutes of no-flow global ischemia followed by reperfusion (n=7) and (2) decreased excitability induced by perfusion with 5 micromol/L of tetrodotoxin (TTX) followed by washout (n=3). "
10/04/1991 - "Infusion of tetrodotoxin, a blocker of voltage-dependent Na+ channels, was without effect on the DA surge during ischemia, but decreased the DA levels after reperfusion to the same extent as in control rats. "
01/02/1991 - "Thirty min before ischemia, tetrodotoxin at a dose of 10(-7) or 10(-6) M was topically applied into the hippocampal CA1 subfield. "
10/20/2015 - "Na+ current, reversibly blocked by tetrodotoxin, was retained in cancer cells in tumor tissue slices, thus directly confirming functional VGSC activity in vivo. "
01/01/1995 - "In the tumor cells from SCLC cell line NCI-H146, the majority of the voltage-gated Na+ channels are only weakly tetrodotoxin (TTX)-sensitive (Kd = 215 nM). "
07/01/1991 - "The Na+ channel blocker tetrodotoxin (5 microM) did not affect inward currents in tumor corticotrophs. "
01/01/2004 - "Tetrodotoxin is safe and effective for severe, refractory cancer pain."
06/01/2011 - "We assessed the long-term safety and efficacy of subcutaneous tetrodotoxin treatment in reducing the intensity of chronic cancer-related pain. "
|1.||Sodium Channels (Sodium Channel)
|7.||Acetylcholine (Acetylcholine Chloride)
|8.||Adenosine Triphosphate (ATP)