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Tetrazoles

Networked: 14 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Azoles: 2138
    - Tetrazoles: 14

Experts

1.	Apostolopoulos, Vasso: 1 article (11/2022)
2.	Chasapis, Christos T: 1 article (11/2022)
3.	Gadanec, Laura Kate: 1 article (11/2022)
4.	Kelaidonis, Konstantinos: 1 article (11/2022)
5.	Ligielli, Irene: 1 article (11/2022)
6.	Matsoukas, John M: 1 article (11/2022)
7.	Mavromoustakos, Thomas: 1 article (11/2022)
8.	Moore, Graham J: 1 article (11/2022)
9.	Ridgway, Harry: 1 article (11/2022)
10.	Zulli, Anthony: 1 article (11/2022)

Related Diseases

1.	Pneumocystis Pneumonia (Pneumocystis carinii Pneumonia) 07/01/2019 - "The present study was aimed to synthesize and evaluate tetrazoles of baicalin against Pneumocystis carinii pneumonia in the rat model. "
2.	Neoplasms (Cancer) 12/09/2021 - "Novel Substituted Tetrazoles as ACSS2 Inhibitors for Treating Cancer." 10/19/2023 - "The synthesized tetrazoles were screened for their in-vitro cytotoxic activity against epidermoid cancer cell line (A431) and colon cancer line (HCT116) with respect to normal skin fibroblast cell line (BJ-1) using MTT assay, and antimicrobial activity against the bacteria: K. " 01/01/2020 - "Molecular docking and pharmacophoric modelling of 1,5-disubstituted tetrazoles as inhibitors of two proteins present in cancer, the ABL and the mutated T315I kinase."
3.	Edema (Dropsy) 01/01/1978 - "The protection afforded by these tetrazoles at a dose of 100 mg/kg i.p., against carrageenin-induced edema in rats, ranged from 11 to 46%. " 01/01/1975 - "Initial screening on carrageenin-induced rat paw edema showed that alpha-methylacetic substitution in the 5 position was preferable to substitutions with the equivalent esters, amides, alcohols, amines or tetrazoles. "
4.	Weight Loss (Weight Reduction) 12/01/2023 - "A few carboxylic acids and tetrazoles were selected as especially promising with the tetrazole TM38837 subsequently demonstrating impressive efficacy in various animal models of obesity, producing considerable weight loss and improvements on plasma markers of inflammation and glucose homeostasis, at doses apparently producing negligible brain exposure. "
5.	Virus Diseases (Viral Diseases) 11/01/2022 - "Arginine blockers, such as traditional sartans that bear anionic tetrazoles and carboxylates, may be ideal candidate drugs for retarding viral infection by weakening S-protein RBD binding to ACE2 and discouraging hydrolysis of cleavage sites. "

Related Drugs and Biologics

1.	baicalin
2.	Proteins (Proteins, Gene)
3.	Carrageenan
4.	Carboxylic Acids
5.	Angiotensin II Type 1 Receptor Blockers
6.	Thiadiazoles
7.	RNA-Directed DNA Polymerase (Reverse Transcriptase)
8.	Phosphotransferases (Kinase)
9.	Oxides
10.	Oxadiazoles