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Tetrahydrocortisone

Also Known As:
Pregnane-11,20-dione, 3,17,21-trihydroxy-, (3alpha,5beta)-
Networked: 32 relevant articles (1 outcomes, 1 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Carletto, Antonio: 2 articles (08/2008 - 03/2008)
2. Olivieri, Oliviero: 2 articles (08/2008 - 03/2008)
3. Ravagnani, Viviana: 2 articles (08/2008 - 03/2008)
4. Friso, Simonetta: 2 articles (08/2008 - 03/2008)
5. Pizzolo, Francesca: 2 articles (08/2008 - 03/2008)
6. Corrocher, Roberto: 2 articles (08/2008 - 03/2008)
7. Rask, E: 1 article (05/2013)
8. Simonyte, K: 1 article (05/2013)
9. Axelson, M: 1 article (05/2013)
10. Lönn, L: 1 article (05/2013)

Related Diseases

1. Obesity
2. Hypertension (High Blood Pressure)
08/01/2008 - "Lower activity of 11 beta-hydroxysteroid dehydrogenase 2 (11beta-HSD2) classically induces hypertension by leading to an altered tetrahydrocortisol- versus tetrahydrocortisone-metabolites (THFs/THE) shuttle. "
01/01/2006 - "Measurement of urinary free tetrahydrocortisol and tetrahydrocortisone ratio (allo-THF+THF)/THE is clinically important in the diagnosis of hypertension caused by congenital absence of 11beta-hydroxysteroid dehydrogenase type 2 (apparent mineralocorticoid excess, AME) or inhibition of the enzyme after licorice ingestion. "
08/01/1991 - "To study the possible impairment of 11 beta-hydroxysteroid-dehydrogenase in patients with chronic renal insufficiency, urinary excretion rates of the four main glucocorticoid-metabolites, tetrahydrocortisol, tetrahydrocortisone, allotetrahydrocortisol and allotetrahydrocortisone were determined by capillary gas chromatography in 22 patients with chronic renal insufficiency with (N = 15) and without (N = 7) hypertension, but without hemodialysis treatment. "
03/01/2008 - "The aim of the present work was to define the possible role of abnormal cortisol/cortisone handling, as revealed by an urinary tetrahydrocortisol + allotetrahydrocortisol (THFs)/tetrahydrocortisone (THE) ratio between 1.5 and 3.0, by measuring urinary cortisol and cortisone metabolites in: normotensive individuals (n = 100) who received 7-8 mg/day of oral prednisone and were then followed for development of hypertension; essential hypertensive (EH) participants from primary care (n = 103); and EH hypertensive patients referred to the Hypertension Unit (n = 141). "
3. Chronic Renal Insufficiency
4. Cushing Syndrome
5. Hypothyroidism

Related Drugs and Biologics

1. Tetrahydrocortisol
2. cortolone
3. cortol
4. allotetrahydrocortisol
5. 11-beta-Hydroxysteroid Dehydrogenases (11beta Hydroxysteroid Dehydrogenase)
6. Hydrocortisone (Cortisol)
7. Cortisone
8. Androsterone
9. 11-beta-Hydroxysteroid Dehydrogenase Type 2 (11 beta-Hydroxysteroid Dehydrogenase Type 2)
10. Pregnanetriol

Related Therapies and Procedures

1. Renal Dialysis (Hemodialysis)