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Tetrahydrocortisol

Also Known As:
Pregnan-20-one, 3,11,17,21-tetrahydroxy-, (3alpha,5beta,11beta)-
Networked: 39 relevant articles (2 outcomes, 1 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Olivieri, Oliviero: 2 articles (08/2008 - 03/2008)
2. Ravagnani, Viviana: 2 articles (08/2008 - 03/2008)
3. Carletto, Antonio: 2 articles (08/2008 - 03/2008)
4. Pizzolo, Francesca: 2 articles (08/2008 - 03/2008)
5. Corrocher, Roberto: 2 articles (08/2008 - 03/2008)
6. Friso, Simonetta: 2 articles (08/2008 - 03/2008)
7. Rask, E: 1 article (05/2013)
8. Lönn, L: 1 article (05/2013)
9. Simonyte, K: 1 article (05/2013)
10. Axelson, M: 1 article (05/2013)

Related Diseases

1. Lewis Lung Carcinoma
2. Obesity
3. Hypertension (High Blood Pressure)
08/01/2008 - "Lower activity of 11 beta-hydroxysteroid dehydrogenase 2 (11beta-HSD2) classically induces hypertension by leading to an altered tetrahydrocortisol- versus tetrahydrocortisone-metabolites (THFs/THE) shuttle. "
04/01/1996 - "Tetrahydrocortisol was unable to inhibit the dexamethasone (DEX)-induced systemic hypertension and decrease in body mass in rats and was unable to displace 3H-DEX from the soluble human glucocorticoid receptor. "
01/01/2006 - "Measurement of urinary free tetrahydrocortisol and tetrahydrocortisone ratio (allo-THF+THF)/THE is clinically important in the diagnosis of hypertension caused by congenital absence of 11beta-hydroxysteroid dehydrogenase type 2 (apparent mineralocorticoid excess, AME) or inhibition of the enzyme after licorice ingestion. "
08/01/1991 - "To study the possible impairment of 11 beta-hydroxysteroid-dehydrogenase in patients with chronic renal insufficiency, urinary excretion rates of the four main glucocorticoid-metabolites, tetrahydrocortisol, tetrahydrocortisone, allotetrahydrocortisol and allotetrahydrocortisone were determined by capillary gas chromatography in 22 patients with chronic renal insufficiency with (N = 15) and without (N = 7) hypertension, but without hemodialysis treatment. "
03/01/2008 - "The aim of the present work was to define the possible role of abnormal cortisol/cortisone handling, as revealed by an urinary tetrahydrocortisol + allotetrahydrocortisol (THFs)/tetrahydrocortisone (THE) ratio between 1.5 and 3.0, by measuring urinary cortisol and cortisone metabolites in: normotensive individuals (n = 100) who received 7-8 mg/day of oral prednisone and were then followed for development of hypertension; essential hypertensive (EH) participants from primary care (n = 103); and EH hypertensive patients referred to the Hypertension Unit (n = 141). "
4. Chronic Renal Insufficiency
5. Neoplasms (Cancer)

Related Drugs and Biologics

1. Tetrahydrocortisone
2. cortolone
3. cortol
4. Minocycline (Cyclops)
5. Angiogenesis Inhibitors
6. Genistein
7. Suramin (Suramin Sodium)
8. O-(chloroacetylcarbamoyl)fumagillol (TNP 470)
9. delta interferon
10. allotetrahydrocortisol

Related Therapies and Procedures

1. Renal Dialysis (Hemodialysis)
2. Ovariectomy (Oophorectomy)