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Tetragastrin

L-Tryptophyl-L-methionyl-L-aspartyl-L-phenylalaninamide. The C-terminal tetrapeptide of gastrin. It is the smallest peptide fragment of gastrin which has the same physiological and pharmacological activity as gastrin.
Also Known As:
AOC-Tetragastrin; AOC-Tetrapeptide; CCK (30-33); CKK-4; Cholecystokinin (30-33); Cholecystokinin 4; 4, Cholecystokinin; AOC Tetragastrin; AOC Tetrapeptide; Cholecystokinin Tetrapeptide; Tetrapeptide, Gastrin; CCK-4; Cholecystokinin-Tetrapeptide; Gastrin Tetrapeptide; L-Phenylalaninamide, L-tryptophyl-L-methionyl-L-alpha-aspartyl-
Networked: 125 relevant articles (6 outcomes, 17 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Rupprecht, Rainer: 7 articles (01/2011 - 02/2003)
2. Shlik, Jakov: 6 articles (07/2013 - 08/2002)
3. Eser, Daniela: 6 articles (01/2011 - 01/2005)
4. Ströhle, Andreas: 5 articles (01/2012 - 02/2003)
5. Schüle, Cornelius: 5 articles (01/2011 - 01/2005)
6. Rupprecht, R: 5 articles (06/2009 - 03/2000)
7. Vasar, Veiko: 4 articles (07/2013 - 07/2004)
8. Tõru, Innar: 4 articles (07/2013 - 07/2004)
9. Maron, Eduard: 4 articles (07/2013 - 07/2004)
10. Zwanzger, P: 4 articles (09/2012 - 05/2003)

Related Diseases

1. Neoplasms (Cancer)
2. Stomach Neoplasms (Stomach Cancer)
02/15/1990 - "At week 52, prolonged administration of tetragastrin alone resulted in a significant reduction in the incidence and number of gastric cancers and a significant increase or decrease in the labelling indices of the fundic and antral mucosae, respectively. "
03/01/1989 - "Three hundred and one gastric cancer patients have been examined preoperatively to investigate their gastric acid secretions after stimulation by tetragastrin, and serum gastrin stimulation by a test meal, as well as for skin reactions and an evaluation of their serum glycoproteins. "
03/01/1985 - "In view of the anomalous expression of blood group and related antigens in the gastric mucosae of patients with malignant and premalignant diseases of the stomach, and the potential clinical value of their measurement, a preliminary study has been performed on the blood group antigens A, B, H, Lea, Leb, and I(Ma) in glycoprotein rich extracts of the resting and tetragastrin stimulated gastric juice of patients without evidence of gastric cancer. "
02/15/1990 - "The effects of combined administration of tetragastrin and the ornithine decarboxylase inhibitor 1,3-diaminopropane (DAP) on the incidence and number of gastric cancers induced by N-methyl-N'-nitro-N-nitrosoguanidine (MNNG), and the BUdR labelling indices of the fundic and antral mucosae, were investigated in inbred Wistar rats. "
07/15/1982 - "Five gastro-entero-pancreatic hormones or related peptides (tetragastrin, glucagon, secretin, cholecystokinin-pancreozymin and cerulein) significantly increased the number of stomach cancer cells from 15% to 310% of the number of control cells cultivated in a serum-free, hormone-free medium. "
3. Gastritis
4. Metaplasia
5. Panic Disorder (Panic Attack)

Related Drugs and Biologics

1. Methylnitronitrosoguanidine (MNNG)
2. Histamine (Histamine Dihydrochloride)
3. Antral
4. Interleukin-1beta (Interleukin 1 beta)
5. Cholecystokinin (Pancreozymin)
6. Bethanechol (Duvoid)
7. Citalopram (Escitalopram)
8. Lactic Acid
9. Glycoproteins (Glycoprotein)
10. Carbon Dioxide

Related Therapies and Procedures

1. Aftercare (After-Treatment)
2. Proximal Gastric Vagotomy
3. Truncal Vagotomy
4. Injections
5. Vagotomy