Terpenes (Terpenoids)

01/20/2022 - "Plant-derived terpenoids are a group of plant defense molecules that have been proven effective in killing many different types of cancer cells, both in in vitro experiments and in vivo models. "
11/21/2002 - "In a search for novel accessible compounds potent against MDR tumor cells, we synthesized a series of arylalkylamines that contain isoprenoid side chains of different length. "
10/01/2021 - "Recently, several in vitro and in vivo studies have been dedicated to understanding the 'terpenoid induced autophagy' phenomenon in cancer cells. "
01/01/2020 - "The study aims to use a patent review to evaluate the development and use of terpenes, or formulations containing terpenes, in new therapeutic options for the treatment of various types of cancer. "
12/01/2012 - "The present article provides an overview of the recent progress in the anti-cancer studies on terpenoids. "

02/01/2022 - "Natural products have been shown to be a promising source of treatments for the management of chronic pain, as an example the terpenes. "
03/29/2023 - "A number of studies have shown that terpenes can produce pain relief in various pain states in both humans and animals. "
01/18/2023 - "The aim of this study is thus to compare the effect of two dietary supplements, both containing hemp seed oil, but of which only one also contains terpenes, in relieving pain and improving joint function in patients suffering from KOA. "
03/01/2014 - "In this review, the authors summarize therapeutic patent applications concerning the employment of terpenes for pain relief, focusing on the perspective for these compounds to become candidates for new drugs intended to control painful syndromes. "
03/01/2014 - "Terpenes and derivatives as a new perspective for pain treatment: a patent review."

11/01/2019 - "Future studies are needed to reveal the mechanisms by which volatile compounds, especially α-terpineol act to mitigate inflammation and to determine the bioavailability of terpenes."
07/30/2021 - "& Zucc., a traditional medicinal plant used as an inflammation-relieving remedy, is a rich source of terpenoids. "
01/01/2020 - "Terpenoids are natural products with multi-target activities against inflammation. "
01/01/2019 - "We discuss how clues from human genetics have led to new insights into how alterations in isoprenoid biosynthesis connect to inflammation. "
01/01/2018 - "In contrast to CBD that exerts prolonged immunosuppression and might be used in chronic inflammation, the terpenoids showed only a transient immunosuppression and might thus be used to relieve acute inflammation."

01/01/2013 - "This study demonstrated the antibiofilm potential of terpenoids, which need to be further explored as therapeutic strategy against biofilm associated infections of C. "
11/20/2023 - "So, these terpene compounds hold potential as therapeutic agents against infections caused by N. "
11/01/2023 - "harknessii and the fungal symbionts altered the terpene chemistry in a similar pattern while trees responded to the infection by the A. "
01/01/2022 - "Antimicrobial Terpenes Suppressed the Infection Process of Phytophthora in Fennel-Pepper Intercropping System."
01/01/2022 - "Our data highlight the coordinated induction of terpenes and phenolics in spruce upon infection by E. "

01/01/2021 - "The Effect of Terpenoid Natural Chinese Medicine Molecular Compound on Lung Cancer Treatment."
03/15/1999 - "These data, which are in keeping with the cocarcinogenic potential of betaC, may help to explain the unexpected lung cancer increases obtained in chemoprevention trials in heavy smokers supplemented with the isoprenoid. "
01/01/2021 - "To address the above issue, this study reviews the five biological pathways that common terpenoid compounds in medicinal plants interfere with the occurrence and development of lung cancer: cell proliferation, cell apoptosis, cell autophagy, cell invasion, metastasis, and immune mechanism regulation. "
01/01/2018 - "The present investigation was carried out to study the pharmacological properties of a potent and major bioactive compound: xylaranic acid, which was obtained from Xylaria primorskensis (X. primorskensis) terpenoids in terms of antibacterial activity, antioxidant potential against DPPH & H2O2 radicals and anticancer activity against human lung cancer cells. "
09/29/2012 - "To further confirm the biological molecule present in PD we analyzed its chromatographic fraction through mass spectroscopy, NMR and FT-IR studies and characterized it to be a tri-terpenoid, a derivative of betulinic acid with a molecular formula C(30)H(46)O(2.) Thus, overall results suggest that nano-encapsulation of PD (NPD) increases drug bioavailability and thereby has a better chemo-preventive action against lung cancer in vivo and on A549 cells in vitro than that of PD."